Zhongguo shiyan zhenduanxue, 2022 目的 了解儿科重症监护室住院患者感染病原菌分布和药敏特点。方法采用WHONET 5.0软件对2019年广东省人民医院儿科重症监护室送检验科微生物室培养的数据进行导出分析。结果 2019年儿科重症监护室送检标本中培养出病原菌的数量是194株。分析检出比例占前十的病原菌分布发现，呼吸道标本（包括痰、肺泡灌洗液和纤支镜冲洗液）的检出比例最高，占76.29%(148/194)，菌种检出比例最高的是金黄色葡萄球菌，占15.98%(31/194)，其次是肺炎克雷伯菌，占13.40%(26/194 ...
李正康 +4 more
doaj
, 2018 抗生素的不合理使用和细菌耐药性是当今医学界所面临的严重问题,严重危害着人类的健康和生存。从哲学角度,运用对立统一规律,深入地剖析了细菌耐药性和抗生素之间相互对立、相互斗争、相互依存、相互促进的关系。同时,以系统的观点提出预防细菌耐药性的全面措施,包括:首先,严格控制抗菌药物的使用;其次,发挥正确的导向;最后,树立微生态观,减缓细菌耐药性的发展进程。2017年福建省思想政治课教学科研团队择优支持计划项目(JZ170136);;2016年福建省自然科学基金面上项目 ...
吴宝捷, 房丽丽, 梁美英
core
Effects of dynamic monitoring of plasma procalcitonin levels in sepsis patients in guiding antibiotic treatment on course of treatment，drug resistance and prognosis [PDF]
"Objective To explore the effects of dynamic monitoring of plasma procalcitonin（PCT）levels in patients with sepsis in guiding antibiotic treatment on course of treatment and drug resistance，and to evaluate its significance in predicting patient prognosis.
SU Li *，ZHANG Ruiying，LI Queque
core +2 more sources
Zhongguo shiyan zhenduanxue, 2012 近年来肺炎克雷伯菌已成为医院感染的重要病原菌,同时院内分离的肺炎克雷伯菌往往有较高的产超广谱β-内酰胺酶（ESBL）率并呈现多重耐药性[1,2]。在肠杆菌科细菌耐药机制中,整合子起着非常重要的作用[3],通过位点特异性基因重组机制使细菌耐药基因盒（gene cassette）整合在一起,形成多种耐药基因的组合和排列 ...
杨朵, 王占伟, 郭宇, 张正
doaj
Progress in diagnosis and treatment of strabismus based on artificial intelligence technology [PDF]
Strabismus, misalignment of the eyes arising from central nervous system dysregulation and extraocular muscles imbalance, commonly manifests in childhood, leading to amblyopia, binocular vision dysfunction, torticollis and other developmental and ...
CHEN Moxin +6 more
core +1 more source
Zhongguo shiyan zhenduanxue, 2007 目的研究我院产新型β-内酰胺酶肺炎克雷伯菌（KP）的耐药现状,为临床用药提供合理依据。方法614株临床分离的无重复肺炎克雷伯菌,采用NCCLS表型筛选和确证试验检测ESBLs,酶提取物改良三维试验检测AmpC酶株,纸片协同试验检测金属β-内酰胺酶;KB纸片法检测产酶株对11种抗菌药的体外抗菌活性;琼脂二倍稀释法测定9种抗生素对同时产AmpC酶和ESBLs菌株的最低抑菌浓度（MIC）。结果单产ESBLs的检出率为31.8%,单产AmpC酶的检出率为2.6%,同时产ESBLs和AmpC酶的检出率为1.1 ...
李从荣, 黄俊, 吕霞
doaj
[UhpTE350Q mutation along with the presence of fosA6/5 genes in the genome probably contributes to inherent fosfomycin resistance of Klebsiella pneumoniae]. [PDF]
Nan Fang Yi Ke Da Xue Xue Bao, 2023 DA R, Zhou Y, Cheng Y, Lv J, Han B.
europepmc +1 more source
[Plasmids carried by carbapenems-resistant Klebsiella pneumoniae in burn patients and its correlation with strain transmission]. [PDF]
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi, 2022 Huang SY +7 more
europepmc +1 more source
Postoperative Application of Anti-infective Agents in 30 Patients Undergoing Stem Cell Transplantation in Our Hospital from 2003 to 2008 [PDF]
, 2010 目的:评价我院干细胞移植患者术后早期抗感染药的应用情况。方法:调查我院2003~2008年30例干细胞移植患者从预处理至术后早期抗感染药的应用情况,包括病原学检查、抗感染药费用、应用例/次、应用时间、用药频度(dddS)、药物利用指数(duI)及抗感染药联用情况,分析其应用合理性。结果:干细胞移植患者术后26例出现感染,感染率达86.67%,病原学检查阳性11例;抗感染药总费用327598.23元;术后早期使用频率列前10位的抗感染药中,duI1的3个;联合用药中,二联38例/次(占73.08 ...
欧阳华, 陈锦辉
core
Isolation, identification and control of spoilage microorganisms in Xiangwei stewed bean [PDF]
Objective: To better control the growth of spoilage microorganisms, and ensure the food safety of Xiangwei Luodou dry. Methods: The putrefactive microorganisms in Xiangwei dried tofu were identified by plate scribing method, colony morphology observation,
LI Bingxin +5 more
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