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Chinese Guidelines on the Diagnosis and Treatment of Primary Lung Cancer (2011 Version)
一、概述 原发性肺癌(以下简称肺癌)是我国最常见的恶性肿瘤之一.2010年卫生统计年鉴显示,2005年,肺癌死亡率占我国恶性肿瘤死亡率的第1位. 为进一步规范我国肺癌诊疗行为,提高医疗机构肺癌诊疗水平,改善肺癌患者预后,保障医疗质量和医疗安全,特制定本规范. 二、诊断技术与应用 (一)高危因素有吸烟史并且吸烟指数大于400支/年、高危职业接触史(如接触石棉)以及肺癌家族史等,年龄在45岁以上者,是肺癌的高危人群.中文核心期刊要目总览(PKU)中国科技核心期刊(ISTIC)012677 ...
Tianyou WANG +39 more
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This paper reviewed current research status of pain catastrophizing in patients with lung cancer after surgery, and summarized the concept, theoretical basis, assessment tools, epidemiological characteristics, influencing factors and management ...
BIAN Guanjun (边冠军) +2 more
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美国研究人员最新开发出一种纳米粒子,外表呈棒状,可以随血液流动“侦察”到肿瘤部位,帮助将药物指引到病灶处,从而有效消灭肿瘤 美国麻省理工学院等机构的研究人员在英国新一期《自然•材料》杂志报告说,肿瘤部位的血管通常会有病态变大的孔洞,纳米粒子进入这些孔洞中会刺激周边组织,使机体发出一种类似有伤口要求凝血物质聚集的信号。此时,另外一种携带药物的“攻击型”纳米粒子就会循信号而来,帮助消灭肿瘤。 通常情况下 ...
中国科学院老科协工程力学分会
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目的本研究旨在探讨医院职工肺癌患病情况,提高职工肿瘤防治水平。方法收集全球疾病负担数据库中国肺癌疾病数据和某三甲肿瘤专科医院职工2009-2021年年度体检数据、随访病理资料和生存随访数据进行比较分析。结果近年来,该院职工和中国人群肺癌的年龄标准化患病率均不断上升。该院职工肺癌年龄标准化患病率高于中国人群,但年龄标准化死亡率较低。职工肺癌患病率年度增长率也高于中国人群(平均年度变化百分比AAPC 13.0% vs.
张颖, 叶慧珍
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ABSTRACT Calcium overload‐induced immunogenic cell death (ICD) holds great potential in antitumor immunotherapy, and it is a critical strategy for regulating multiple intracellular Ca2+ channels through inhibiting the endogenous Ca2+ efflux and promoting the exogenous Ca2+ influx.
Xingguo Xu +9 more
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ABSTRACT Esophageal squamous cell carcinoma (ESCC) remains associated with frequent local recurrence and distant metastasis despite advances in radiochemotherapy and immunotherapy, highlighting the need for therapeutic strategies that improve both local tumor control and systemic antitumor immune responses.
Dongdong Wang +7 more
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ABSTRACT Lung cancer is one of the most common and deadly malignancies worldwide. Although immune checkpoint inhibitors, including PD‐1/PD‐L1 blockers, have benefited a subset of patients, response rates remain limited, and recurrence is frequent because of the immunosuppressive tumor microenvironment (TME), characterized by hypoxia and dysregulated ...
Yi Ma +6 more
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ABSTRACT Lung cancer remains the leading cause of cancer‐related deaths worldwide, yet immune checkpoint blockade (ICB) is often compromised by an immunosuppressive tumor microenvironment (TME) with acidosis, hypoxia, and poor T cell infiltration. Here, we develop a TME‐responsive nanoplatform (MgH2@Lip/PD‐L1) that couples hydrogen gas therapy with PD ...
Xuyu Gu +5 more
wiley +1 more source
细胞凋亡是一种细胞自主生理性死亡 ,对多细胞动物机体的正常发育和自身稳定具有极其重要的作用 ,细胞凋亡失衡与许多疾病尤其是与肿瘤的发生发展有关。近几年来 ,有关细胞凋亡分子机制的研究进展较快 ,对细胞凋亡在放疗、化疗等肿瘤治疗措施中的作用也有了进一步的认识 ...
李祺福, 洪水根, 欧阳高亮
core
肺癌是临床上最常见的恶性肿瘤,在我国肺癌的发病率和死亡率仍居恶性肿瘤的首位[1]。肿瘤标志物对肺癌早期的诊断起着至关重要的作用。多肿瘤标志物定量检测试机盒(蛋白芯片-化学发光法)是一种高通量的微化型的蛋白质检测技术,可以同时检测12种肿瘤标志物,适用于肿瘤的早期辅助诊断以及鉴别诊断。本研究通过对120例肺癌患者、82例肺部良性病变患者以及150例健康体检者12种肿瘤标志物的结果分析,探讨多肿瘤标志物蛋白芯片法对肺癌诊断的价值。
崔连鸷, 高海燕, 朱华, 于秀艳
doaj

