Results 41 to 50 of about 7,186 (171)
hsa-miR-125a-5p Enhances Invasion Ability in Non-Small Lung Carcinoma Cell Lines [PDF]
Background and objective MicroRNAs (miRNAs) are short non-coding RNAs that posttranscriptionally regulate gene expression by partially binding complementary to target sites in mRNAs.
Enhua WANG +4 more
core
目的利用彩色多普勒血流显像(CDFI)和脉冲波多普勒技术(PW),对周围型肺肿块周边血流进行研究,以鉴别肿块的良恶性。方法对51例周围型肺肿块(良性18例,恶性33例)周边血流进行CDFI和PW检查。结果良恶性肺肿块周边血流的显示率分别为33%和88%,两者间有显著差异。恶性肿瘤血流程度多Ⅱ-Ⅲ级,而良性肿瘤多为0-Ⅰ级,两者间有显著差异。恶性肿瘤RI0.470.06,PI1.180.16,PSV0.170.04m/s,EDV0.070.02m/s:良性肿瘤RI0.810.12,PI1.680.33 ...
程文 +5 more
doaj
Imaging and Pathological Features of Percutaneous Cryosurgery on Normal Lung Evaluated in a Porcine Model [PDF]
Background and objective Lung cancer is one of the most commonly occurring malignancies and frequent causes of death in the world. Cryoablation is a safe and alternative treatment for unresectable lung cancer.
Baojun MEI +13 more
core
目的探讨五种血清肿瘤标志物癌胚抗原(CEA)、糖类抗原125(CA125)、神经元特异性烯醇化酶(NSE)、细胞角蛋白19片段(CYFRA21-1)及鳞状细胞癌相关抗原(SCC)检测对肺癌临床诊断的价值。方法采用电化学发光法检测血清中CEA、CA125、NSE、CYFRA21-1及化学发光法检测SCC的水平,比较分析五种血清学肿瘤标志物在肺癌临床诊断中的价值。结果试验中5种肿瘤标志物均能很好的鉴别肺癌患者与健康人群;CA125在诊断肺癌与其它肿瘤显著(AUC=0.706 ...
陈超 +4 more
doaj
Analysis of Differentially Expressed Proteins in Self-Paired Sera of Advanced Non-small Cell Lung Cancer Patients Responsive to Gefin [PDF]
Background and objective All the advanced NSCLC patients that received EGFR-TKI therapy will eventually relapse after a period of efficacy. The aim of this study is to investigate the serum biomarkers as potential predictive factors for the efficacy of ...
Ailin GUO +10 more
core
【目的】 通过体内实验探讨人纤溶酶原Kringle 5(K5)对小鼠Lewis肺癌移植瘤生长与转移的抑制作用?【方法】 采用腋下接种肿瘤细胞的方法建立Lewis肺癌细胞皮下种植瘤小鼠模型,分为PBS对照组和K5治疗组,观察各组肿瘤生长情况,测量肿瘤大小,制备小鼠体质量-时间曲线和肿瘤体积-时间曲线;采用皮下种植瘤剔除术建立Lewis肺癌自发性肺转移模型,术后分为PBS对照组和K5治疗组,观察各组小鼠肺组织转移瘤数量,取肺组织进行病理学分析?【结果】 在皮下种植瘤模型中,与对照组相比 ...
doaj
目的探讨血清蛋白电泳图谱用于肺癌等恶性肿瘤诊断和疗效监测的价值。方法圆盘聚丙烯酰胺凝胶电泳(PAGE)用于血清蛋白检测。结果某些PAGE血清蛋白谱型为肿瘤患者所特有。肺癌、消化系肿瘤、卵巢癌和肾癌血清PAGE特异图谱阳性率均高于80%。肺癌患者治疗前后血清蛋白PAGE图谱有显著改变。结论血清蛋白PAGE图谱可用于肺癌等肿瘤的辅助诊断和疗效监测。
王金河 +6 more
doaj
Association between Polymorphisms of ERCC1 and Response in Patients with Advanced Non-small Cell Lung Cancer Receiving Cisplatin-based Chemotherapy [PDF]
Background and objective Results of studies on genetic polymorphisms of ERCC1 gene in DNA repair pathway which may affect response to platinum-based chemotherapy and survival in patients with non-small cell lung cancer are conflicting.
Hui ZHANG +6 more
core
目的 联合检测胸腔积液中的CYFRA2 1 -1、NSE ,研究CYFRA2 1 -1、NSE作为肿瘤标记物对肺癌诊断以及病期判断的诊断价值。方法 用全自动免疫酶标仪测定80胸腔积液中CYFRA2 1- 1、NSE的含量,其中肺癌4 9例,其他肿瘤31例。结果 非小细胞肺癌患者血清中CYFRA2 1 -1含量显著高于其他肿瘤组及小细胞肺癌组(P
宋鉴清 +5 more
doaj
Diagnotic Value of the Combined Determination of Telomerase Activity in Induced Sputum, Pleural Effusion and Fiberobronchoscopic Biopsy Samples in Lung Cancer [PDF]
Background and objective It has been proven that telomerase activation correlates with the carcinogenesis, aggressiveness and turnover of lung cancer.
Cheng ZHAO +4 more
core

