Clinical Observation of Erlotinib in the Treatment of Advanced Non-small Cell Lung Cancer: A Report of 92 Eases [PDF]
Background and objective Erlotinib, a selective inhibitor of epidermal growth factor receptor tyrosine kinase, has been approved effective in local advanced or metastatic non-small cell lung cancer (NSCLC).
Aiqin GU +5 more
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肉瘤样癌是一种分化较差的含有肉瘤形态细胞或肉瘤样分化的恶性肿瘤,多见于子宫、乳腺、鼻咽等部位,而肺部原发的肉瘤样癌(Lung20sarcomatoid20carcinoma,LSC)是肺部极少见的恶性肿瘤,只占非小细胞肺癌的0.3%-4.7%[1]。2012年9月我科室手术治疗了一例肺肉瘤样癌患者。现结合此病例复习相关文献做以下报道。
侯力键 +4 more
doaj
hsa-miR-125a-5p Enhances Invasion Ability in Non-Small Lung Carcinoma Cell Lines [PDF]
Background and objective MicroRNAs (miRNAs) are short non-coding RNAs that posttranscriptionally regulate gene expression by partially binding complementary to target sites in mRNAs.
Enhua WANG +4 more
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“肺硬化性血管瘤”的组织发生学研究——细胞学、组织学、免疫组化及电镜观察
本文报告一例典型的肺硬化性血管瘤,女性,37岁,左下肺双发性肿瘤。基于细胞学,组织学、免疫组化及电镜的观察,确证肿瘤有向上皮性和纤维性双相分化的能力,认为是一种来源于间皮的肿瘤。
张汝逢
doaj
肺癌是一种发病率及死亡率极高的恶性肿瘤,其中非小细胞肺癌最为常见,超过80%,严重威胁患者生命健康[1-3]。尽管胸腔镜根治术、放化疗在肺癌治疗中的应用广泛,而临床上诊治肺癌的效果及预后尽不相同,肺癌患者长期生存率、生存质量远低于健康者[4]。肿瘤异常蛋白(TAP)在多种恶性肿瘤细胞中均有表达[5],而有关其与肺癌患者预后相关性尚不明确。因此 ...
刘哲, 郝媛媛, 卢畅
doaj
Detection of EGFR and COX-2 Expression by Immunohistochemical Method on a Tissue Microarray Section in Lung Cancer and Biological Significance [PDF]
Background and objective Epidermal growth factor receptor (EGFR) and cyclooxygenase-2 (COX-2), which can regulate growth, invasion and metastasis of tumor through relevant signaling pathway, have been detected in a variety of solid tumors.
Congzhong ZHU, Juan LIU, Xinyun WANG
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Comparative Proteomics Study on Human High-metastatic Large Cell Lung Cancer Cell Lines Before and After Transfecting with nm23-H1 Gene [PDF]
Background and objective As a tumor metastasis suppressor gene, the functions of nm23-H1 gene are still unclear. The aim of this study is to better understand the mechanism of lung cancer metastasis and to find new biomarkers for early diagnosis and new ...
Li MA +6 more
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目的利用彩色多普勒血流显像(CDFI)和脉冲波多普勒技术(PW),对周围型肺肿块周边血流进行研究,以鉴别肿块的良恶性。方法对51例周围型肺肿块(良性18例,恶性33例)周边血流进行CDFI和PW检查。结果良恶性肺肿块周边血流的显示率分别为33%和88%,两者间有显著差异。恶性肿瘤血流程度多Ⅱ-Ⅲ级,而良性肿瘤多为0-Ⅰ级,两者间有显著差异。恶性肿瘤RI0.470.06,PI1.180.16,PSV0.170.04m/s,EDV0.070.02m/s:良性肿瘤RI0.810.12,PI1.680.33 ...
程文 +5 more
doaj
Imaging and Pathological Features of Percutaneous Cryosurgery on Normal Lung Evaluated in a Porcine Model [PDF]
Background and objective Lung cancer is one of the most commonly occurring malignancies and frequent causes of death in the world. Cryoablation is a safe and alternative treatment for unresectable lung cancer.
Baojun MEI +13 more
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Association between Polymorphisms of ERCC1 and Response in Patients with Advanced Non-small Cell Lung Cancer Receiving Cisplatin-based Chemotherapy [PDF]
Background and objective Results of studies on genetic polymorphisms of ERCC1 gene in DNA repair pathway which may affect response to platinum-based chemotherapy and survival in patients with non-small cell lung cancer are conflicting.
Hui ZHANG +6 more
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