Results 51 to 60 of about 7,825 (189)

人纤溶酶原K5体内抑制Lewis肺癌肿瘤生长与转移

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2008
【目的】 通过体内实验探讨人纤溶酶原Kringle 5(K5)对小鼠Lewis肺癌移植瘤生长与转移的抑制作用?【方法】 采用腋下接种肿瘤细胞的方法建立Lewis肺癌细胞皮下种植瘤小鼠模型,分为PBS对照组和K5治疗组,观察各组肿瘤生长情况,测量肿瘤大小,制备小鼠体质量-时间曲线和肿瘤体积-时间曲线;采用皮下种植瘤剔除术建立Lewis肺癌自发性肺转移模型,术后分为PBS对照组和K5治疗组,观察各组小鼠肺组织转移瘤数量,取肺组织进行病理学分析?【结果】 在皮下种植瘤模型中,与对照组相比 ...
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血清蛋白聚丙烯酰胺凝胶电泳图谱对肿瘤诊断与疗效监测的价值

open access: yesZhongguo shiyan zhenduanxue, 2008
目的探讨血清蛋白电泳图谱用于肺癌等恶性肿瘤诊断和疗效监测的价值。方法圆盘聚丙烯酰胺凝胶电泳(PAGE)用于血清蛋白检测。结果某些PAGE血清蛋白谱型为肿瘤患者所特有。肺癌、消化系肿瘤、卵巢癌和肾癌血清PAGE特异图谱阳性率均高于80%。肺癌患者治疗前后血清蛋白PAGE图谱有显著改变。结论血清蛋白PAGE图谱可用于肺癌等肿瘤的辅助诊断和疗效监测。
王金河   +6 more
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Diagnotic Value of the Combined Determination of Telomerase Activity in Induced Sputum, Pleural Effusion and Fiberobronchoscopic Biopsy Samples in Lung Cancer [PDF]

open access: yes, 2010
Background and objective It has been proven that telomerase activation correlates with the carcinogenesis, aggressiveness and turnover of lung cancer.
Cheng ZHAO   +4 more
core  

胸腔积液CYFRA21-1、NSE检测在肺癌诊断中的应用

open access: yesZhongguo shiyan zhenduanxue, 2005
目的 联合检测胸腔积液中的CYFRA2 1 -1、NSE ,研究CYFRA2 1 -1、NSE作为肿瘤标记物对肺癌诊断以及病期判断的诊断价值。方法 用全自动免疫酶标仪测定80胸腔积液中CYFRA2 1- 1、NSE的含量,其中肺癌4 9例,其他肿瘤31例。结果 非小细胞肺癌患者血清中CYFRA2 1 -1含量显著高于其他肿瘤组及小细胞肺癌组(P
宋鉴清   +5 more
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Left Main Bronchus Root Prolongation to Cure 3 Patients whose Carina is Involved by Lung Cancer [PDF]

open access: yes, 2011
Background and objective Patient whose carina is involved by carcinoma is difficult to treat by surgery. The aim of this study is to evaluate the safety and effectiveness of left main bronchus root prolongation to cure these patients.
Chengcheng XU   +4 more
core  

CT在肺硬化性血管瘤诊断中的价值

open access: yesZhongguo shiyan zhenduanxue, 2005
目的 探讨肺硬化性血管瘤 (PulmonarySclerosingHemangioma ,PSH)的CT影像诊断特点。方法 经手术病理证实的 5例肺硬化性血管瘤 ,全部行CT检查。结果 肺硬化性血管瘤CT表现为密度均匀的孤立软组织肿块或结节 ,部分可有浅分叶 ,少数可有沙砾状钙化 ,纵隔、肺门未见异常肿大淋巴结。结论 CT对肺硬化性血管瘤的诊断和鉴别诊断更有价值。
赵素岗   +5 more
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Detection of MTAP Protein and Gene Expression in Non-small Cell Lung Cancer [PDF]

open access: yes, 2011
Background and objective The abnormal expression of MTAP, a tumor suppressor gene, is found in a variety of tumor tissues. The aim of this study is to detect the expression of MTAP mRNA protein and the clinical significance for the therapy of non-small ...
Baoqing DING   +3 more
core  

基于二代测序分析肺癌脑转移与非脑转移分子差异

open access: yesZhongguo shiyan zhenduanxue, 2019
中国是肺癌高发国家,每年新增患者73.3万,死亡人数达到61.0万,肺癌已经成为中国恶性肿瘤中的第一杀手[1]。相比于传统的检测方法,利用二代测序技术对肺癌进行基因层面的突变检测,已在疾病早筛、靶向治疗、复发监测等领域体现出强大的优势。循环肿瘤DNA来自于凋亡或者坏死的肿瘤细胞,在很大程度上可以反映肿瘤的分子特征 ...
尤涛   +5 more
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Analysis of Differentially Expressed Proteins in Self-Paired Sera of Advanced Non-small Cell Lung Cancer Patients Responsive to Gefin [PDF]

open access: yes, 2009
Background and objective All the advanced NSCLC patients that received EGFR-TKI therapy will eventually relapse after a period of efficacy. The aim of this study is to investigate the serum biomarkers as potential predictive factors for the efficacy of ...
Ailin GUO   +10 more
core  

卵巢癌复发肾上腺转移1例

open access: yesZhongguo shiyan zhenduanxue, 2016
卵巢癌是妇科三大恶性肿瘤之一,发病率位于宫颈癌和宫体癌之后,但死亡率居妇科恶性肿瘤中首位。卵巢癌的转移以直接蔓延和腹腔种植为主,其次为淋巴引流扩散,血行播散较为少见,晚期及治疗后复发的患者可转移至肺、肝、脑等[1]。肾上腺转移癌常见的原发肿瘤依次是:肺癌,乳腺癌,胃肠道恶性肿瘤,恶性黑色素瘤,肾癌 ...
姚广, 曲波, 谢占玲, 刘爱民
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