Analysis of Differential Gel Electrophoresis of Paclitaxol Resistant and Sensitive Lung Adenocarcinoma Cells' Secretome [PDF]
Background and objective Paclitaxol (PTX) resistance is one of main factors which affect the outcome of chemotherapy of lung adenocarcinoma. The aim of this study is to compare the secreted protein expression profiles between Paclitaxol (PTX) resistant ...
Huifang SHA +5 more
core
CA199、NSE、CYFRA21-1、TPS和CEA联合检测在肺癌诊断中的应用价值
目的探讨肿瘤标记物CA199、NSE、CYFRA21-1、TPS和CEA在肺癌诊断中的应用价值。方法选择67例肺癌患者、42例肺良性病变患者和30例健康体检者为研究对象,分别测定3组研究对象的血清肿瘤标记物水平。结果肺癌组血清肿瘤标志物CA199、NSE、CYFRA21-1、TPS和CEA水平均明显高于肺良性病变组和健康对照组,差异有显著性 ...
段昕, 贾春芳, 段敏
doaj
The Analysis of Erlotinib on Brain Metastases in Patients with Non-small-cell Lung Cancer [PDF]
Background and objective Brain metastases are common in non-small-cell lung cancer (NSCLC) and the prognosis is poor. Erlotinib is a specific inhibitor of the epidermal growth factor receptor-associated tyrosine kinase (EGFRTKI), which has been gradually
Baohui HAN, Hao BAI
core
The Expressions of IL-7 and IL-7R and the Relationship between them with Lymph Node Metastasis and Prognosis in Non-small Cell Lung Cancer [PDF]
Background and objective It has been proven that lymph node metastasis was closely related to prognosis of lung cancer. Interleukin-7 (IL-7) and interleukin-7 receptor (IL-7R) could promote lymph node metastasis through vascular endothelial growth factor-
Jian MING +4 more
core
DNA Methylation and Non-small Cell Lung Cancer [PDF]
Genomic DNA methylation is a major form of epigenetic modification. Hypermethylation could affect the binding of transcription factors to DNA and change the structure of chromatin resulting in silence of tumor suppressor genes, which plays an important ...
Longbang CHEN, Youwei ZHANG
core
肺硬化性血管瘤(Sclerosing hemagioma of thelungSHL),是一种少见的肺内良性肿瘤,在临床诊断中极易与肺炎性假瘤,肺泡细胞癌和类癌等发生混淆,从而造成误诊 ...
王晓军 +4 more
doaj
A Randomized Phase I/II Trial to Compare Weekly Usage with Triple Weekly Usage of Paclitaxel in Concurrent Radiochemotherapy for Patients with Locally Advanced Non-small Cell Lung Cancer [PDF]
Background and objective Although the guidelines of the National Comprehensive Cancer Network of USA recommend that the standard therapy for locally advanced non-small cell lung cancer (LANSCLC) is concurrent chemoradiotherapy.
Anhui SHI +4 more
core
目的 探讨系统性免疫炎症指数(SII)对晚期非小细胞肺癌患者预后的预测价值。方法 自2019年1月至2022年6月,回顾性收集新疆医科大学附属肿瘤医院收治的晚期非小细胞肺癌患者143例,对患者随访1年,观察患者是否发生肿瘤特异性死亡,将患者分为死亡组(n=67)和对照组(n=76),比较两组患者系统性免疫炎症指数和其他临床特征差异,分析晚期非小细胞肺癌死亡的危险因素,同时分析系统性免疫炎症指数对肿瘤特异性死亡的预测价值。结果 与对照组比较,死亡组原发肿瘤最大径增大(5.66±2.53 cm vs.4 ...
杨燕, 顾国民
doaj
肺癌主要分为非小细胞肺癌(NSCLC,约85%)和小细胞肺癌(SCLC,约15%)。肺腺癌发病率逐年增长,已经成为NSCLC中最常见的亚型,几乎占全部肺癌的50%,且总体生存率较低[1]。2015版WHO肺肿瘤组织学以肿瘤的生长方式为基础,将肺腺癌重新分类:(1)浸润前病变,包括原位腺癌和非典型腺瘤样增生;(2)早期浸润病变,被命名为微小浸润腺癌;(3)浸润性腺癌,包括伏壁型、腺泡型 ...
付丹阳, 张捷
doaj
A Prospective Randomized Study of the Radiotherapy Volume for Limited-stage Small Cell Lung Cancer: A Preliminary Report [PDF]
Background and objective Controversies exists with regard to target volumes as far as thoracic radiotherapy (TRT) is concerned in the multimodality treatment for limited-stage small cell lung cancer (LSCLC).
Fenghua WANG +16 more
core

