[Chronic kidney disease in community: Current state for screening and management]. [PDF]
Xu LY +8 more
europepmc +1 more source
常染色体显性多囊肾病(autosomal dominant polycystic kidney disease,ADPKD)是最常见的遗传性肾病,发病率为1/400~1/1000。ADPKD主要致病基因有两个,分别称为PKD1和PKD2。该病代代发病,子代发病机率为50%。患者多在成年后出现双侧肾脏囊肿,随年龄增长,逐渐损害肾脏结构和功能;至60岁时,约半数患者进展至终末期肾脏疾病(end stage renal disease,ESRD),占ESRD病因的第四位。ADPKD还可合并肝囊肿、心脏瓣膜异常、
李林, 梅长林
doaj
[Sichuan Dark Tea-Based Medicated Dietary Formula Improves Obesity-Induced Renal Lipid Metabolism Disorder in Mice by Remodeling Gut Microbiota and Short-Chain Fatty Acid Metabolism]. [PDF]
Li H +9 more
europepmc +1 more source
目的观察RANK/RANKL在STZ诱导的2型糖尿病肾病大鼠肾脏中的表达。方法采用高糖高脂喂养加STZ腹腔注射法建立2型糖尿病动物模型(T2DM),大鼠造模成功后随机分为糖尿病肾病组(DK)和正常对照组(NC)。分别于4周、8周、12周末各处死6只老鼠,检测血糖、胰岛素、血脂、尿蛋白、肌酐。HE染色观察肾脏病理改变,免疫组化法检测肾脏中RANK、RANKL的表达分布,Western印迹法检测RANK、RANKL。组间比较采用T检验,组内比较采用单因素方差进行统计学分析。结果与NC组比较 ...
刘素芳, 刘丽秋, 杨鹏鹏
doaj
[Linagliptin improves diabetic kidney disease in rats by promoting mitochondrial biogenesis through the AMPK/PGC-1α/TFAM pathway]. [PDF]
Wan L +6 more
europepmc +1 more source
Ferroptosis and secondary nephrosis. [PDF]
Zhang Y, Yang L.
europepmc +1 more source
[A high temporal resolution dynamic T<sub>2</sub>*W imaging study based on step oxygen stimulation of rat kidneys]. [PDF]
Sun S, Tao Q, Zhao K, Hu Q, Feng Y.
europepmc +1 more source
[Performance evaluation of different filtration fractions during daytime continuous renal replacement therapy]. [PDF]
Wang L, Chen Y, Xu G, Xu C.
europepmc +1 more source
[Mechanism of Trifolin in Attenuating Hypertension-Induced Renal Cell Apoptosis via Modulation of the MAPK Signaling Pathway]. [PDF]
Wu M +8 more
europepmc +1 more source
[Effect of co-morbid chronic kidney disease on the accuracy of cardiac troponin levels for diagnosis of acute myocardial infarction]. [PDF]
Deng Y, Chen H, Li G, Chen L, Fu Q.
europepmc +1 more source

