, 2018 胃食管反流病(gastroesophageal reflux disease, GERD)的发病率无论在发展中国家还是发达国家均在逐渐升高,尤其是北美和亚洲,疾病谱包括糜烂性反流病或反流性食管炎或糜烂性食管炎、非糜烂性反流病(nonerosive reflux disease, NERD)和Barrett食管三个亚型。GERD的病因、发病机制、临床表现以及对治疗的反应均显示出高度的异质性或个体间差异,特别是NERD和难治性GERD;另外,尽管生物医学 ...
吴方雄, 周永顺, 牛春燕
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Chemical Constituents and Digestion-Promoting Effect of Maojian Green Tea [PDF]
In this study, the digestion-promoting function of an aqueous extract from Maojian green tea extract (MJ-GTE) was evaluated by small intestinal motility in mice as well as body mass, body mass gain, food intake, food utilization rate, gastric pepsin ...
GAO Jianjian, ZHOU Zhengyang, SONG Yanhua, YU Shuai, LU Wei, LIN Zhi, DAI Weidong
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Application of pylorus-preserving gastrectomy in surgical treatment for early gastric cancer and interpretation of guidelines and consensus [PDF]
Endoscopic resection (ER) and laparoscopic surgery are the main methods for treatment of early gastric cancer (EGC). Radical gastrectomy(RG) and lymph node dissection are required for the patients who don’t meet the indications of ER, but it may cause ...
YU Suyue, LU Aiguo
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Multimodal molecular imaging technology (SPECT/CT) in the clinical application progress [PDF]
多模态分子成像设备的发展是影像学发展的里程碑，继SPECT和CT后，人们开始致力于SPECT/CT的研究。CT的多参数解剖成像与SPECT的分子成像结合，不仅提供SPECT的功能影像,而且提供CT的解剖显像,提高了传统定位、定性的准确性。对促进神经、心血管、肿瘤等方面的研究及临床诊断具有重要意义。本文从SPECT/CT成像的研究现状及其面临的挑战进行综述，并探讨SPECT/CT在生物医学中的优越性及发展前景。Multimodal molecular imaging development is ...
Guo, Jin-gang +5 more
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The multi-target mechanism of Synephrine and Paeoniflorin exert antidepressive and prokinetic effect similar to Zhiqiao Shaoyao [PDF]
, 2017 目的：目前市场上许多可用的单胺类抗抑郁药物起效缓慢且副作用多。以柴胡舒肝散抗抑郁促动力（A&P）为线索，发现阿魏酸和水合橙皮内酯后，仍然不清楚是否还存在A&P的药物，本文以炎性通路为主线，通过氧化应激，犬尿酸，ghrelin等多方面对比研究中药及单体A&P疗效。初步阐明其A&P潜在作用机理，枳壳芍药药对及有效成分辛弗林、芍药苷可能是潜在的天然抗抑郁药物。 方法：1.枳壳芍药药对与辛弗林、芍药苷急性抗抑郁促动力疗效对比：FST实验、TST实验、在体胃肠动力实验；2.慢性抗抑郁促动力疗效对比：FST实验 ...
王云
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Effects of mechanical processing on the physicochemical properties of oat β-glucan and its in vitro fermentation [PDF]
Objective: To evaluate the effects of mechanical processing on the physicochemical properties of oat β-glucan and its in vitro fermentation. Methods: Oat coarse grains, oat flakes, and oat flour were respectively produced through mechanical progressing ...
CHENG Anwei +4 more
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经络理论智慧之光——读《金针之魂——经络的研究》 [PDF]
, 1999 胡翔龙、程莘农2位国家攀登项目首席科学家主编的科普丛书《金针之魂——经络的研究》业已出版问世，这既是中医针灸界也是整个医学界的一件盛事。在国家攀登计划30个项目中，“经络的研究”排在5项生命科学中的第2项，足见其重要性和时代要求。2000多年前我们祖..
刘孔藤
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Nobiletin and ferulic acid through anti-inflammatory and oxidative stress and ghrelin exerts antidepressant and prokinetic effects similar to Zhiqiaodanggui [PDF]
, 2017 目的：对枳壳当归药对及其吸收成分川陈皮素和阿魏酸进行抗抑郁促胃肠动力的疗效进行对比并初步研究它们特别是单体川陈皮素和阿魏酸的抗抑郁作用机制。 方法：1.枳壳当归药对抗抑郁促动力作用探究及枳壳当归与其单体川陈皮素和阿魏酸的疗效比较：急性抗抑郁：FST，在体胃肠动力检测；慢性抗抑郁：体重变化、糖水偏好度、食物消耗、旷场实验和强迫游泳实验；2.枳壳当归药对抗抑郁促胃肠动力机制：单胺递质、激素水平的检测；3.川陈皮素抗抑郁机制研究：氧化指标的检测；4.阿魏酸抗抑郁机制研究：细胞因子的检测；5.细胞实验 ...
肖哲
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, 2005 目的评估管状胃+幽门成形术在食管癌切除术中的应用价值。方法对52例常规经右胸食管癌切除术中行管状胃加幽门成形术,术后观察胃肠减压量及患者胸胃症状。结果术后胃肠减压量较少。全组吻合口瘘1例(为颈部吻合),胸胃-右支气管瘘并死亡1例;术后明显胸胃无力症状1例,其余病例均无明显胸胃返流及压迫症状;术后短期腹泻6例;术后发生吻合口狭窄4例。其余病例恢复良好。结论经右胸食管癌切除术中行管状胃+幽门成形术,可减轻胸胃潴留所致压迫症状及减少返流,其操作较安全 ...
付成国 +3 more
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Research Progress on the Application and Mechanism of Medium-Chain Fatty Acids in Adjuvant Therapy of Diseases [PDF]
As people’s consumption levels and health awareness have risen, the consumer demand for functional foods is steadily increasing. Medium-chain fatty acids (MCFAs), an important class of dietary fatty acids, have been regarded as high-value functional ...
JIA Xiwen, XU Jiajie, LIANG Xueyan, ZHANG Hui, LIN Hao, DING Kaili, HE Yinghui, LIU Luoyang, HAN Lujia, XIAO Weihua
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