白细胞介素-1B -511T/C多态性与不同临床 病理学类型胃癌的关系
Zhongshan Daxue xuebao. Yixue kexue ban, 2009 【目的】 研究中国人白细胞介素(IL)-1B -511T/C多态性与不同临床病理学特征胃癌的遗传易感性的关系及其对胃癌患者预后的影响65377; 【方法】 采用聚合酶链反应-限制性长度片段多态性(PCR-RFLP)对563例胃癌及500例健康对照进行IL-1B -511位点基因分型,分析该多态性与不同临床病理学类型胃癌发病风险关系并对其预后进行生存分析65377;【结果】 IL-1B -511T/C多态性与胃癌遗传易感性相关,携带IL-1B -511T等位基因者发生胃癌的风险较CC基因型增加(OR =
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