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白介素8-251 位点基因多态性与我国高低发区胃癌关系 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2005 【目的】研究白介素(interleukin, IL)-8 基因- 251A/T 位点多态性在中国高、低发区普通人群和胃癌 (gastric cancer , GC)患者中的分布, 并探讨其基因多态性与我国胃癌的关系。【方法】用聚合酶链反应- 反向杂 交法(polymerase chain reaction and reverse dot blot, PCR-RDB)检测我国胃癌低发区( 广东省) 104 例健康人和 104 例胃癌患者和胃癌高发区( 陕西省) 102 例健康人和102 ...
曾志荣 +6 more
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胰十二指肠同源基因1在胃癌中的表达及对胃癌生物学 行为的影响
Zhongshan Daxue xuebao. Yixue kexue ban, 2014 【目的】 明确PDX1基因在胃癌中的表达模式,探讨PDX1表达上调对胃癌细胞增殖和凋亡的影响,从而揭示PDX1在胃癌发生发展中的作用?【方法】 免疫组化法检测胃癌组织芯片的PDX1蛋白表达,RT-PCR和免疫印迹法检测3株胃癌细胞(AGS?SGC7901?BCG823)PDX1 mRNA表达;构建PDX1正义表达载体,瞬时转染胃癌细胞,免疫印迹法检测转染后PDX1?Ki-67?PCNA?Caspase3的表达,同时检测转染后胃癌细胞的增殖指数和凋亡指数?筛选PDX1稳定表达株,评价胃癌细胞伤口愈合 ...
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Zhongshan Daxue xuebao. Yixue kexue ban, 2001 【目的】探讨胃肠道类癌的临床及病理特点、诊断与治疗方法。【方法】对1980 ～ 2000 年32 例胃肠道类癌的临 床资料和31 例患者1 ～ 5 年的随访资料进行回顾性分析。【结果】所有患者均接受手术治疗并经病理证实, 包括阑尾类癌10 例, 结肠类癌8 例, 直肠类癌7 例, 胃类癌4 例, 小肠类癌2 例, 十二指肠类癌1 例。32 例胃肠道类癌中, 良性类癌25 例, 恶性 类癌7 例。8 例患者术前经内镜活检证实, 4 例出现恶性类癌综合征。在平均29 个月的随访中, 7 例患者死于转移。
李仲宏 +3 more
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Zhongshan Daxue xuebao. Yixue kexue ban, 2002 【目的】探讨胃癌标本病理大切片的方法及作用。【方法】20 例的胃癌术后标本作病理大切片和 HE 染色。【结果】病理大切片 在同一切片上可观察到胃近切端-肿瘤-远切端,癌灶与两切瑞的距离,侵袭胃壁深度,以及手术切口是否有癌细胞等。【结论】对胃癌病理形态 的观察,大切片优于常规 HE 切片。
赖英荣, 梁英杰
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Chinese Clinical Named Entity Recognition with ALBERT and MHA Mechanism
Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022 Traditional clinical named entity recognition methods fail to balance the effectiveness of feature extraction of unstructured text and the complexity of neural network models. We propose a model based on ALBERT and a multihead attention (MHA) mechanism to solve this problem.
Dongmei Li +4 more
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Chinese Medical Entity Recognition Model Based on Character and Word Vector Fusion
Scientific Programming, Volume 2021, Issue 1, 2021., 2021 The medical information carried in electronic medical records has high clinical research value, and medical named entity recognition is the key to extracting valuable information from large‐scale medical texts. At present, most of the studies on Chinese medical named entity recognition are based on character vector model or word vector model.
Qinghui Zhang +5 more
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, 2021 Evidence-Based Complementary and Alternative Medicine, Volume 2021, Issue 1, 2021.
Ting-Ting Wu +10 more
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General Psychiatry, Volume 30, Issue 2, Page 119-126, July 2018., 2018 Background The incidence of depressive symptoms is higher in cancer patients. And depression can also affect the occurrence, development and outcome of cancer through the neuroendocrine‐immune‐network system. Objective To study the level of Nesfatin‐1 in the plasma and brain tissue and its role in the pathogenesis in gastric cancer comorbid with ...
Nan Zhang +6 more
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Zhongguo shiyan zhenduanxue, 2021 目的探讨胃癌根治性手术前后TM4SF1(跨膜4超家族成员1)水平及病理特征变化。方法选取天津市宁河区医院2016年6月到2019年6月共收治的80例胃癌患者进行回顾性分析,所有患者均行胃癌根治术,分析胃癌患者根治术前胃癌组织及邻近非胃癌组织中TM4SF1表达,胃癌患者根治术后胃粘膜中TM4SF1水平表达与胃癌根治术前TM4SF1表达水平对比,并对比所有患者胃癌根治术前和手术1年后的临床病理特征。结果在同一切段中,TM4SF1在GC组织中呈阴性表达,在相邻非癌组织中呈阳性表达。在我们的患者队列中 ...
郭俊龙, 梁滨, 田伟军
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