Results 11 to 20 of about 1,432,199 (156)

Incorporating MicroRNA into Molecular Phenotypes of Circulating Tumor Cells Enhances the Prognostic Accuracy for Patients with Metastatic Breast Cancer

open access: yesThe Oncologist, Volume 24, Issue 11, Page e1044-e1054, November 2019., 2019
Abstract Background The molecular phenotype of circulating tumor cells (CTCs) was associated with clinical outcome of patients with breast cancer. CTCs isolated from patients with metastatic breast cancer (MBC) display a unique microRNA (miRNA) expression profile.
Weige Tan   +11 more
wiley   +1 more source

International clinical practice recommendations on the definition, diagnosis, assessment, intervention, and psychosocial aspects of developmental coordination disorder – Chinese (Mandarin) translation

open access: yesDevelopmental Medicine &Child Neurology, Volume 61, Issue 3, Page E1-E35, March 2019., 2019
目的 本国际临床指南由欧洲残疾儿童学会(the European Academy of Childhood Disability,EACD)牵头制定,旨在解决发育性协调障碍(developmental coordination disorder,DCD)的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题,通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础,以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类,最终转化为指南建议。并由国际 ...
Jing Hua   +6 more
wiley   +1 more source

Developing HMME‐Conjugated NIR‐II Activated Carbon Dots Nanospray for the Treatment of MRSA Biofilm Infections in Diabetic Wound via PTT/CDT/SDT

open access: yesRare Metals, Volume 45, Issue 4, April 2026.
ABSTRACT Diabetic wound infections are a common complication of diabetes, which severely impact patients' quality of life. Effective treatment of diabetic wound infections remains one major challenge in the clinic, partially due to the formation of bacterial biofilm and antibiotic resistance.
Liang Zhou   +8 more
wiley   +1 more source

NIR‐Responsive Nano‐Integrated Magnesium Phosphate Cement Promotes Bone Regeneration via Osteoblast‐Exosome‐Osteoclast Crosstalk

open access: yesRare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT The limited osteogenic capacity of magnesium phosphate cement (MPC) has constrained its biomedical applications, underscoring the necessity to develop MPC with enhanced physical properties and bone‐forming capabilities. In this study, a multifunctional MPC system was developed by incorporating zoledronic acid‐loaded near‐infrared (NIR ...
Bin Wang   +8 more
wiley   +1 more source

Genetic Confirmations of Dwarf Lemurs Across Madagascar Highlights Complex Biogeographic Patterns 马达加斯加全境鼠狐猴的遗传确认揭示了复杂的生物地理模式

open access: yesIntegrative Conservation, Volume 4, Issue 4, Page 665-674, December 2025.
Using a diagnostic mitochondrial marker gene, we document the presence of furry‐eared dwarf lemurs, a species known from Madagascar's eastern montane rainforests, in several forest fragments across the island's central highlands. These findings raise new questions about when this species colonized these sites, how they tolerate these changing and ...
Marina B. Blanco   +27 more
wiley   +1 more source

Review of additively manufactured zinc alloys by laser powder bed fusion for biomedical applications

open access: yesRare Metals, Volume 44, Issue 11, Page 8262-8291, November 2025.
Graphical abstract AbstractZinc (Zn) and its alloys have emerged as promising candidates for biomedical materials, owing to their controlled degradation kinetics, intrinsic biocompatibility, and the release Zn2+ ions which are known to promote bone regeneration and tissue healing.
Xuan Yang   +5 more
wiley   +1 more source

Comparison of the in vitro antibiofilm activities of otic cleansers against canine otitis externa pathogens

open access: yesVeterinary Dermatology, Volume 36, Issue 2, Page 148-158, April 2025.
Background – Biofilm production by canine otitis externa (COE) pathogens and resistance development to multiple antimicrobials are commonly reported problems in veterinary practice. The use of adjuvants to disrupt biofilms may be a viable adjunctive therapy.
Bhumika F. Savaliya   +3 more
wiley   +1 more source

蓝藻胞外多聚物生物合成、群体形成与微囊藻水华

open access: yes, 2020
有毒微囊藻水华在太湖、巢湖和滇池等饮用水源地频繁暴发,对居民健康和水产养殖等构成严重威胁,亟需开发新技术加以有效控制和利用。在水华暴发时,蓝藻大量分泌胞外多聚物而形成细胞群体,是蓝藻水华发生的关键和前提。蓝藻群体中胶质状胞外多聚物由胞外多糖、蛋白质和其他生物大分子组成,对其结构、功能和生物合成途径研究了解仍然有限。生物信息学和比较基因组学分析发现微囊藻和其他多种蓝藻中编码大量的具有称之为PEP-CTERM结构域的潜在胞外蛋白质,这些潜在的蛋白质可能通过特殊的分选系统分泌到细胞表面 ...
邱东茹
core  

牙周膜细胞与壳聚糖—聚磷酸三钙复合材料生物相容性研究

open access: yesZhongguo shiyan zhenduanxue, 2007
目的研究壳聚糖—聚磷酸三钙复合材料对离体培养的人牙周膜细胞粘附及增殖的影响,探讨二者的生物相容性,为骨组织工程中生物材料的选择提供实验依据。方法采用冻干法制备壳聚糖—聚磷酸三钙复合材料,培养人牙周膜细胞,传代扩增后接种到材料表面,体外继续培养,用倒置光学显微镜、扫描电镜观察细胞的粘附和生长情况,用MTT方法检测种植后2、4、68、d细胞的增殖情况。结果种植2 d后细胞呈梭形纤维细胞样,平均每100倍视野下,有生物材料的实验组与无材料的对照组胞数分别为(380±16)个和(80±20)个 ...
马宁, 张莉, 边立新
doaj  

PAC对生物膜性能及煤气化废水处理效能影响研究

open access: yesGongye shui chuli, 2023
以弹性立体填料为载体、连续流进水方式运行两组生物膜反应器。通过不断提高进水负荷、降低C/N的方式驯化生物膜,探究投加20 mg/L聚合氯化铝(PAC)对生物膜性能及低C/N煤气化废水处理效果的影响。通过对污染物去除效能监测发现,未投加PAC的R1组和投加PAC的R2组两组生物膜耐冲击负荷能力良好,有机物去除效果稳定;后期稳定运行时R2组和R1组TN去除率分别达84%、79.4%以上,脱氮性能良好,且PAC的投加使除磷率达98%以上。由数据分析可知,20 mg/L PAC的投加有利于提高生物膜生物量 ...
王力杨   +5 more
doaj  

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