目的探讨脂蛋白(a)水平与2型糖尿病患者胰岛素抵抗之间的相关性,揭示其在糖尿病代谢调控中的潜在作用。方法采用单中心横断面研究设计,纳入106例2型糖尿病患者,根据脂蛋白(a)水平分为高水平组(脂蛋白(a)>100 mg/dL)与低水平组(脂蛋白(a) ≤100 mg/dL)。收集一般信息及实验室指标,包括脂蛋白(a)、空腹血糖(fasting plasma glucose,FPG)、空腹胰岛素(fasting insulin,FINS)等,及计算胰岛素抵抗稳态模型评估指数(Homeostasis ...
王立芳, 孙凤, 王清
doaj +2 more sources
目的观察高脂饮食诱导肥胖大鼠一般情况、糖、脂代谢的变化及α-硫辛酸(ALA)对其影响。方法 Wistar大鼠50只,随机选10只普通饲料喂养作为正常对照组,其余40只采用高脂喂养10周后评价肥胖大鼠模型,成模肥胖大鼠再随机分为两组:HFD组、HFD+ALA组,后者腹腔注射(ALA 30mg/kg,ip)2周。测定各组大鼠血清空腹血糖(FBG)、空腹胰岛素(FIns)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、游离脂肪酸(NEFA ...
闫国超, 邵云, 秦小霞
doaj
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Li JB +8 more
europepmc +1 more source
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Chen Q +5 more
europepmc +1 more source
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Li N, Zhang L, Guo Q, Zhou Y, Liu C.
europepmc +1 more source
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Zhang HR +7 more
europepmc +1 more source
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Chen X, Chen P.
europepmc +1 more source
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He Y, He H, Cao Y, Wang F.
europepmc +1 more source
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Zhao Y +8 more
europepmc +1 more source
[Level of circulating Alarin in obese children and its association with insulin resistance]. [PDF]
Li MQ, Li JY, Xie L.
europepmc +1 more source

