Results 21 to 30 of about 1,994 (202)
Highlights Meta‐analysis of α‐ and β‐cell transcriptomes reveals modified energy metabolism, immune response, autophagy, and cellular stress pathways in cells from type 2 diabetes mellitus. The proportion of immature and senescent β‐cells is increased in islets from type 2 diabetes mellitus.
Emily Sara Marques+4 more
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Clinical analysis of insulin resistance in liver cirrhosis patients [PDF]
Objective·To investigate the insulin resistance in liver cirrhosis patients.Methods·Patients with liver cirrhosis from Xinhua Hospital,Shanghai Jiao Tong University School of Medicine in 2013‒2017 were retrospectively assessed.
HUANG Heming+4 more
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复方威灵仙颗粒对高尿酸血症患者血尿酸和胰岛素抵抗的影响 [PDF]
目的观察复方威灵仙颗粒对高尿酸血症(HUA)患者血尿酸(UA)临床疗效及胰岛素抵抗的影响。方法 HUA患者63例,随机分成复方威灵仙颗粒组31例和别嘌呤醇组32例,在基础治疗的基础上,分别给予复方威灵仙颗粒(1剂/d,2次/d)及别嘌呤醇片(100 mg/次,3次/d),8 w为1个疗程。观察治疗前后血UA及临床疗效、空腹血糖(FPG)、空腹胰岛素(FINS)及胰岛素抵抗指数。结果复方威灵仙颗粒组与别嘌呤醇组治疗后的血UA均较治疗前有明显下降(P〈0.01),治疗总有效率分别为86.7%与90 ...
冯桂贞, 吕崇山, 罗艾君
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Improvement and Mechanism of Ganoderma lucidum Polysaccharides and Its Flora Metabolites on Insulin Resistance in HepG2 Cells [PDF]
Objective: To investigate the effects of Ganoderma lucidum polysaccharides and its flora metabolites on the insulin resistance status of HepG2 cells and its mechanisms.
Dongbo LIU+4 more
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Highlights In patients with hypertension and diabetes, early detection and intervention of insulin resistance and related risk factors in patients with normal BMI may reduce the occurrence of urinary microalbumin and delay the progression of CKD. Abstract Background The relationship between albuminuria and insulin resistance (IR) has not been clarified
Shi Gu+4 more
wiley +1 more source
目的 探讨不同胰岛素抵抗状态对无糖尿病史的非致残性缺血性脑血管病(non-disabling ischemic cerebrovascular events,NICE)患者卒中复发风险的影响。 方法 使用稳态模型胰岛素抵抗(homeostasis model assessment of insulin resistance,HOMA-I R)指数 对胰岛素抵抗进行评估。根据不同胰岛素抵抗状态,使用四分位法将无糖尿病史的NICE患者分为4 组。该研究的主要研究终点为90 d新发卒中(包括缺血性和出血性卒中)
陈玮琪,张国军,潘岳松,林金嬉,梁宪红,李上智,王伊龙,荆京,赵性泉,刘丽萍,王拥军
doaj +1 more source
The Value of Abdominal Visceral Adipose Tissue Area and Homeostasis Model Assessment of Insulin Resistance in Predicting Essential Hypertension Complicated with Obstructive Sleep Apnea Syndrome [PDF]
BackgroundThe prevalence of essential hypertension complicated with obstructive sleep apnea hypopnea syndrome (OSAHS) has been increasing year by year. However, due to the differences in medical conditions and lack of clinical understanding in different ...
GAN Lulu, HE Yan, LIU Shijie, NI Qing, YANG Li
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Analysis of Characteristics and Influencing Factors of Hearing Impairment in Patients with Polycystic Ovary Syndrome [PDF]
BackgroundHearing impairment in patients with polycystic ovary syndrome (PCOS) has been confirmed, However, the influencing factors of hearing impairment in PCOS patients have not been fully explained.ObjectiveTo explore the characteristics of hearing ...
XIE Zhijia, ZHANG Lei, CHEN Xin, CHANG Tao
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Recent Advances in the Pathogenesis of Glucolipid Metabolism Disorder in Obstructive Sleep Apnea-hypopnea Syndrome [PDF]
Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a disease marked by apnea, hypopnea, decreased oxygen saturation, and disordered sleep structure, which is a major risk for cardiovascular disease. Recent studies have found that OSAHS patients have an
WANG Yun, HE Yan, LIU Shijie, GAN Lulu, GAO Huifang, LIANG Min, ZUO Zhiheng, YANG Li
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Highlights Diabetic kidney disease is a common comorbidity of type 2 diabetes mellitus. In studies investigating the effect of renal function on the efficacy of treatment with glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs), these agents improved glycemic control in patients with mild to moderately impaired kidney function, without significant ...
Lance A. Sloan
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