Results 21 to 30 of about 1,994 (202)

Relationships between type 2 diabetes, cell dysfunction, and redox signaling: A meta‐analysis of single‐cell gene expression of human pancreatic α‐ and β‐cells 2型糖尿病、细胞功能障碍和氧化还原信号的关系:人胰腺α‐和β‐细胞单细胞基因表达的meta分析

open access: yesJournal of Diabetes, Volume 14, Issue 1, Page 34-51, January 2022., 2022
Highlights Meta‐analysis of α‐ and β‐cell transcriptomes reveals modified energy metabolism, immune response, autophagy, and cellular stress pathways in cells from type 2 diabetes mellitus. The proportion of immature and senescent β‐cells is increased in islets from type 2 diabetes mellitus.
Emily Sara Marques   +4 more
wiley   +1 more source

Clinical analysis of insulin resistance in liver cirrhosis patients [PDF]

open access: yes, 2023
Objective·To investigate the insulin resistance in liver cirrhosis patients.Methods·Patients with liver cirrhosis from Xinhua Hospital,Shanghai Jiao Tong University School of Medicine in 2013‒2017 were retrospectively assessed.
HUANG Heming   +4 more
core   +1 more source

复方威灵仙颗粒对高尿酸血症患者血尿酸和胰岛素抵抗的影响 [PDF]

open access: yes, 2017
目的观察复方威灵仙颗粒对高尿酸血症(HUA)患者血尿酸(UA)临床疗效及胰岛素抵抗的影响。方法 HUA患者63例,随机分成复方威灵仙颗粒组31例和别嘌呤醇组32例,在基础治疗的基础上,分别给予复方威灵仙颗粒(1剂/d,2次/d)及别嘌呤醇片(100 mg/次,3次/d),8 w为1个疗程。观察治疗前后血UA及临床疗效、空腹血糖(FPG)、空腹胰岛素(FINS)及胰岛素抵抗指数。结果复方威灵仙颗粒组与别嘌呤醇组治疗后的血UA均较治疗前有明显下降(P〈0.01),治疗总有效率分别为86.7%与90 ...
冯桂贞, 吕崇山, 罗艾君
core   +1 more source

Improvement and Mechanism of Ganoderma lucidum Polysaccharides and Its Flora Metabolites on Insulin Resistance in HepG2 Cells [PDF]

open access: yes, 2023
Objective: To investigate the effects of Ganoderma lucidum polysaccharides and its flora metabolites on the insulin resistance status of HepG2 cells and its mechanisms.
Dongbo LIU   +4 more
core   +1 more source

Insulin resistance is associated with urinary albumin‐creatinine ratio in normal weight individuals with hypertension and diabetes: The REACTION study 胰岛素抵抗与尿白蛋白肌酐比值在体重指数正常的高血压合并糖尿病人群中相关:中国REACTION研究

open access: yesJournal of Diabetes, Volume 12, Issue 5, Page 406-416, May 2020., 2020
Highlights In patients with hypertension and diabetes, early detection and intervention of insulin resistance and related risk factors in patients with normal BMI may reduce the occurrence of urinary microalbumin and delay the progression of CKD. Abstract Background The relationship between albuminuria and insulin resistance (IR) has not been clarified
Shi Gu   +4 more
wiley   +1 more source

胰岛素抵抗与非致残性缺血性脑血管病患者卒中复发之间的关系 Association between Insulin Resistance and Recurrent Stroke in Patients with Non-disabling Ischemic Cerebrovascular Events

open access: yesZhongguo cuzhong zazhi, 2019
目的 探讨不同胰岛素抵抗状态对无糖尿病史的非致残性缺血性脑血管病(non-disabling ischemic cerebrovascular events,NICE)患者卒中复发风险的影响。 方法 使用稳态模型胰岛素抵抗(homeostasis model assessment of insulin resistance,HOMA-I R)指数 对胰岛素抵抗进行评估。根据不同胰岛素抵抗状态,使用四分位法将无糖尿病史的NICE患者分为4 组。该研究的主要研究终点为90 d新发卒中(包括缺血性和出血性卒中)
陈玮琪,张国军,潘岳松,林金嬉,梁宪红,李上智,王伊龙,荆京,赵性泉,刘丽萍,王拥军
doaj   +1 more source

The Value of Abdominal Visceral Adipose Tissue Area and Homeostasis Model Assessment of Insulin Resistance in Predicting Essential Hypertension Complicated with Obstructive Sleep Apnea Syndrome [PDF]

open access: yes, 2022
BackgroundThe prevalence of essential hypertension complicated with obstructive sleep apnea hypopnea syndrome (OSAHS) has been increasing year by year. However, due to the differences in medical conditions and lack of clinical understanding in different ...
GAN Lulu, HE Yan, LIU Shijie, NI Qing, YANG Li
core   +1 more source

Analysis of Characteristics and Influencing Factors of Hearing Impairment in Patients with Polycystic Ovary Syndrome [PDF]

open access: yes, 2022
BackgroundHearing impairment in patients with polycystic ovary syndrome (PCOS) has been confirmed, However, the influencing factors of hearing impairment in PCOS patients have not been fully explained.ObjectiveTo explore the characteristics of hearing ...
XIE Zhijia, ZHANG Lei, CHEN Xin, CHANG Tao
core   +1 more source

Recent Advances in the Pathogenesis of Glucolipid Metabolism Disorder in Obstructive Sleep Apnea-hypopnea Syndrome [PDF]

open access: yes, 2022
Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a disease marked by apnea, hypopnea, decreased oxygen saturation, and disordered sleep structure, which is a major risk for cardiovascular disease. Recent studies have found that OSAHS patients have an
WANG Yun, HE Yan, LIU Shijie, GAN Lulu, GAO Huifang, LIANG Min, ZUO Zhiheng, YANG Li
core   +1 more source

Review of glucagon‐like peptide‐1 receptor agonists for the treatment of type 2 diabetes mellitus in patients with chronic kidney disease and their renal effects 胰高血糖素样肽‐1受体激动剂治疗慢性肾脏病合并2型糖尿病患者及其对肾功能影响的研究进展

open access: yesJournal of Diabetes, Volume 11, Issue 12, Page 938-948, December 2019., 2019
Highlights Diabetic kidney disease is a common comorbidity of type 2 diabetes mellitus. In studies investigating the effect of renal function on the efficacy of treatment with glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs), these agents improved glycemic control in patients with mild to moderately impaired kidney function, without significant ...
Lance A. Sloan
wiley   +1 more source

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