Results 11 to 20 of about 1,772 (104)

The serum creatinine to cystatin C to waist circumference ratios predicts risk for type 2 diabetes: A Chinese cohort study. [PDF]

open access: yesJ Diabetes, 2023
Highlights Higher creatinine to cystatin C to waist circumference ratio (CCR/WC ratio) was associated with decreased risk of type 2 diabetes mellitus (T2DM) among Chinese people. A nonlinear association was found between CCR/WC and T2DM risk. Abstract Background There is a lack of research regarding the relationship between creatinine to cystatin C to ...
Chen Y   +5 more
europepmc   +2 more sources

Associations of blood biomarkers with arterial stiffness in patients with diabetes mellitus: A population‐based study 糖尿病患者血液生物标志物与动脉硬化的关系: 一项基于人群的研究

open access: yesJournal of Diabetes, Volume 15, Issue 10, Page 853-865, October 2023., 2023
Highlights Few studies have investigated the association of large‐scale biomarkers and pulse wave velocity (PWV) among diabetic patients. This study investigates the relationships of serum laboratory tests with PWV and explored the associations between PWV and all‐cause mortality among diabetic patients.
Yong‐Qi Liang   +9 more
wiley   +1 more source

Correlation of ACR and TcPO2 in diabetic kidney disease patients: A pilot study 糖尿病肾病患者尿白蛋白与肌酐比值和经皮氧分压的相关性:一项初步研究

open access: yesJournal of Diabetes, Volume 15, Issue 6, Page 488-495, June 2023., 2023
Highlights Transcutaneous oxygen pressure (TcPO2) could be used to assess microcirculation, which revealed endothelial injury. As endothelial injury is a cause of albuminuria in diabetic kidney disease (DKD), albuminuria and creatinine (ACR) might be employed to assess microcirculation in DKD patients in rural hospital where TcPO2 is not available. Our
Jin Sun   +7 more
wiley   +1 more source

Glomerular filtration rate estimated by differing measures and risk of all‐cause mortality among Chinese individuals without or with diabetes: A nationwide prospective study 在中国非糖尿病或糖尿病患者中,用不同的方法评估肾小球滤过率和全因死亡率的风险:一项全国性的前瞻性研究

open access: yesJournal of Diabetes, Volume 15, Issue 6, Page 508-518, June 2023., 2023
Highlights All three estimated glomerular filtration rates (GFRs) (based on creatinine [eGFRcr], cystatin C [eGFRcys], or both [eGFRcr‐cys]) were more strongly associated with risk of all‐cause mortality among individuals with diabetes than among those without diabetes. Regardless of diabetes status, eGFRcys and eGFRcr‐cys were more strongly associated
Yu‐Jie Liu   +10 more
wiley   +1 more source

血与尿胱抑素C在糖尿病早期肾损伤中的意义

open access: yesZhongguo shiyan zhenduanxue, 2014
目的探讨胶体金法检测血与尿胱抑素C在糖尿病早期肾损伤中的意义。方法通过检测114例正常人与116例糖尿病患者血及尿中胱抑素C(Cys20C)与β2微球蛋白(β2-MG),采用对比分析,评价正常人群清晨随机尿中尿胱抑素C水平,以及不同糖尿病组(尿微量白蛋白正常及异常组)血、尿胱抑素C与血、尿β2微球蛋白之间的关系。结果在糖尿病早期肾损伤中检测血或尿胱抑素C与检测血及尿β2微球蛋白,经过对比分析,二者均有显著的正相关性;但是单独检测尿胱抑素C,与尿β2微球蛋白相比,二者间没有统计学差别 ...
庄严, 陈志友, 王黎敏
doaj  

检测尿胱抑素C对评估肾小管损伤的临床意义

open access: yesZhongguo shiyan zhenduanxue, 2012
目的探讨肾功能受损患者尿胱抑素C(cystainC;CYS-C)的变化与肾小管损伤之间的关系。方法采用免疫比浊法检测74例尿蛋白阳性疑似肾功能不全患者血清及尿液中的胱抑素C,用酶法检测血清肌酐、尿素及尿液中的肌酐,同时检测了40例健康人血清及尿液中的胱抑素C、肌酐及血清酐、尿素作为对照。结果肾功能不全患者血清尿素、肌酐、胱抑素C和尿液中的胱抑素C显著高于健康对照组,且尿液中的肌酐显著低于健康对照组。结论通过实验结果分析,尿液中的胱抑素C水平与肾功能不全患者肾小管损伤之间存在显著相关性 ...
高万芹, 高申, 张静春
doaj  

血清胱抑素C测定对糖尿病肾病早期诊断的临床意义

open access: yesZhongguo shiyan zhenduanxue, 2013
目的研究血清胱抑素C在2型糖尿病肾病早期诊断中的临床应用。方法收集115例2型糖尿病患者,根据24小时尿白蛋白排泄量,将患者分为单纯性糖尿病组、早期DN组、临床DN组。比较三组患者血清胱抑素C、血肌酐、肾小球滤过率、肌酐清除率检测出肾功能异常的比例并分析血清胱抑素C与肾小球滤过率的相关性;根据肾小球滤过率的数值 ...
白福艳   +5 more
doaj  

CRRT在地震CS患者肌肉损伤和肾功能衰竭中的诊断评估

open access: yesZhongguo shiyan zhenduanxue, 2009
目的对被地震垮塌物埋压超过100小时的15例挤压综合征(Crush Syndrome CS)伤者血清中心肌标志物和胱抑素C浓度进行检测,并运用连续性肾脏替代治疗(continuous renal replacement therapy,CRRT)进行疗效评估。方法使用BECKMAN-LX20全自动生化分析仪,检测由地震所致的CS伤员接受CRRT疗法后血清中CK、CK-MB、Tnl、Myo和胱抑素C的浓度。结果CS伤员的CK、CK-MB、Tnl、Myo、胱抑素C水平明显增高,与正常对照组比较有显著性差异 ...
胡娟, 王启军
doaj  

尿液生物标记物在早期2型糖尿病肾病诊断中的价值探讨

open access: yesZhongguo shiyan zhenduanxue, 2019
目的检测2型糖尿病早期肾病患者的尿中性粒细胞明胶酶相关脂质运载蛋白(NGAL)和胱抑素-C的水平,并与无糖尿病肾病的患者进行比较,分析尿NGAL和胱抑素C水平与尿微量白蛋白相关性。方法入组126名2型糖尿病患者和30名无糖尿病肾病作为对照组进行横断面比较研究。分为3个研究组:2型糖尿病有微量白蛋白尿组,2型糖尿病无微量白蛋白尿组和无任何肾脏疾病的患者。统计研究对象中2型糖尿病病程时间和血糖状态。对所有受试者的血样集中储存在-20℃的冰箱中,批量检测尿微量白蛋白以及NGAL和胱抑素-C水平 ...
陈英   +5 more
doaj  

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