利用XIAP-/-成纤维细胞,检测在剔除XIAP的情况下Xaf1诱导细胞凋亡的作用,探索Xaf1诱导细胞凋亡的机制?【方法】 Xaf1诱导的XIAP-/-成纤维细胞凋亡由流式细胞DNA含量来表示,免疫荧光显微镜检测XIAP-/-成纤维细胞中Xaf1的亚细胞分布,共转染并细胞周期 DNA 含量流式细胞术检测Bcl2对Xaf1诱导的细胞凋亡的影响,细胞色素C流式细胞术检测Xaf1对细胞色素C释放的调节?【结果】 Xaf1与TNFα显著协同诱导XIAP-/-成纤维细胞凋亡,凋亡峰值27 ...
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O-GlcNAcylated YTHDF2 promotes bladder cancer progression by regulating the tumor suppressor gene <i>PER1</i> via m<sup>6</sup>A modification. [PDF]
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[<i>Qingjie Fuzheng</i> Granules alleviates 5-fluorouracil-induced skeletal muscle injury in tumor-bearing mice by inhibiting mitochondria-dependent apoptosis and activating the AMPK-PGC-1α pathway]. [PDF]
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Zhu Y, Zhu Z, Wu P.
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