Results 101 to 110 of about 4,934 (166)
The Influence of Magnesium Supplementation on Glucose and Lipid Metabolism of Rats with Type 2 Diabetes Mellitus [PDF]
, 2012 目的:研究镁补充对2型糖尿病大鼠糖脂代谢的影响。方法:将用高脂饮食联合链脲佐菌素(STz)方法诱发的2型糖尿病大鼠随机分为四个组,糖尿病对照组喂饲高脂饲料,高、中、低剂量组在高脂饲料中分别加入2000、1000、200 Mg/kg的镁(以镁离子计)。自由饮食喂养四周,处死动物。用放射免疫法测血清胰岛素(InS)水平、用葡萄糖氧化酶法测空腹血浆葡萄糖(fASTIng PlASMAgluCOSE,fPg),并计算胰岛素敏感指数(InSulIn SEnSITIVITy IndEX,ISI ...
丛朋地 +5 more
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Effects of liver-specific LCMT1 gene knockout on glycolipid metabolism, learning and memory in mice [PDF]
Objective To investigate the effects of liver-specific leucine carboxyl methyltransferase 1 (LCMT1) gene knockout on glycolipid metabolism, learning and memory in mice and the possible mechanism.
CAI Haiqing +13 more
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Zhongguo shiyan zhenduanxue小胶质细胞代谢重编程是神经退行性疾病发生发展的重要机制。近年研究发现，调控小胶质细胞代谢重编程可有效抑制神经退行性病变进程。本文综述了小胶质细胞在糖代谢、脂代谢和氨基酸代谢重编程的最新研究进展，探讨其在神经退行性疾病中的关键作用，旨在为基于代谢重编程的治疗与预防策略提供新的研究方向。
侯璐 +6 more
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Zhongguo shiyan zhenduanxue, 2012 代谢综合征（MS）是患者体内多种代谢成分异常聚集而形成的一种病理状态,胰岛素抵抗是2型糖尿病、糖耐量减低（IGT）、肥胖、血脂异常的发病基础。代谢综合征的发病率的升高与年龄相关[1]。代谢综合征发病的核心机制是胰岛素抵抗。本研究拟通过测定一组代谢综合征患者的血清瘦素水平、IL-18、血清淀粉样蛋白、胰岛素（FINS ...
王望东
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Research Progress on Regulatory Effects and Mechanism of Akkermansia muciniphila on Glycolipid Metabolism and Intestinal Health [PDF]
Akkermansia muciniphila (A. muciniphila) is a functional gut commensal bacterium. The imbalance in the distribution and abundance of A. muciniphila in the gastrointestinal tract is closely related to the occurrence of various diseases, including ...
Guihu XU +5 more
core +1 more source
干扰素联合利巴韦林对慢性丙型肝炎患者血脂谱和胰岛素抵抗的影响
Zhongguo shiyan zhenduanxue, 2017 HCV感染不仅引起慢性肝炎、脂肪肝、肝硬化和肝癌等疾病,还可影响糖、脂代谢引起代谢性疾病[1]。干扰素（IFN）联合利巴韦林是慢性丙型肝炎抗病毒干预的标准方案之一。有报道,宿主胰岛素抵抗（IR）会降低HCV感染者对干扰素抗病毒干预的应答率,是影响干扰素抗病毒疗效的独立因素;干扰素干预也常出现血糖升高和胰岛素抵抗等临床表现[2 ...
郭薇, 陈艳珍, 焦健
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Effect of high-fat diet for rats at different stages on glucose and lipid metabolism in offspring and related mechanisms. [PDF]
Zhongguo Dang Dai Er Ke Za Zhi, 2021 Wei M +5 more
europepmc +1 more source
血清小而密低密度脂蛋白胆固醇与2型糖尿病患者胰岛素抵抗的相关性分析
Zhongguo shiyan zhenduanxue, 2020 目的探讨2型糖尿病患者血清小而密低密度脂蛋白胆固醇(sdLDL-C)与胰岛素抵抗的相关性。方法依据糖尿病诊断和分类标准将受试者分为三组,分别为正常糖代谢(NGT)组150例、糖耐量异常(IGT)组138例和2型糖尿病(T2DM)组152例。比较三组受试者的一般资料、脂质代谢和糖代谢水平。分析脂质代谢与糖代谢指标的相关性。通过多重线性回归分析,探讨胰岛素抵抗的相关影响因素。结果 NGT组、IGT组和T2DM组受试者的体质指数(BMI)、腰臀比(WHR)、总甘油三酯(TG)、sdLDL-C、空腹血糖(FBG)
范世珍, 周新荣, 于波海
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Differential metabolites of bronchoalveolar lavage fluid from coal worker's pneumoconiosis patients [PDF]
Background It is a research hotspot to study the changes of metabolites and metabolic pathways in the process of coal worker's pneumoconiosis (CWP) by metabonomics and to explore its pathogenesis.
Baoping LI +11 more
core +1 more source
妊高症患者联合检测血清ACA、抗β2GPⅠ及脂代谢水平的临床意义
Zhongguo shiyan zhenduanxue, 2020 目的通过联合检测血清抗心磷脂抗体(ACA)、抗β2糖蛋白Ⅰ抗体(抗β2GPⅠ)及脂代谢(TC、TG、LDL、HDL、ApoA1和ApoB)的水平,探讨其表达水平对不同发病程度妊高症结局的影响。方法将我院产科收治并诊断为妊娠期高血压的孕妇200例作为实验组,依据发病程度又分为轻度子痫前期组70例、重度子痫前期组70例和子痫组60例;同期住院分娩的正常孕妇80例作为对照组。采用Epoch酶标仪和HITACHI全自动生化分析仪检测以上4组受试对象的血清学及脂代谢指标,评估4组受试者血清ACA ...
李介岩, 李晓丽
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