Results 31 to 40 of about 4,934 (166)

Research Progress of the Prevention and Treatment of Metabolic Diseases Based on Short Chain Fatty Acids [PDF]

open access: yes, 2022
Short chain fatty acids (SCFAs) are a class of saturated fatty acids containing 1-6 carbon atoms, which are mainly produced by specific flora in the intestine through the fermentation of dietary fiber, and play an important role in maintaining the ...
ZENG Lin, ZHANG Pengxiang, HUANG Qian, WANG Gaoxiang, LI Huilin
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Fat storage and drought tolerance in a seasonally‐adapted primate: Implications for modeling the effects of animal responses to global climate change 灵长类动物在季节性适应下的脂肪储存和耐旱性:模拟动物应对全球气候变化影响的启示

open access: yesIntegrative Conservation, Volume 3, Issue 3, Page 168-182, September 2024.
Using long‐term field data, we examined the impact of severe droughts on the health, reproductive success, and behavior of the critically endangered Verreaux's sifaka (Propithecus verreauxi) in Madagascar's seasonally dry tropical forest. Despite reduced availability of high‐quality foods, sifaka exhibited stable body condition and reproductive success,
Carrie C. Veilleux   +2 more
wiley   +1 more source

Effects of Dietary intervention on the expressions of INSR and IRS-1 in rats with NAFLD [PDF]

open access: yes, 2015
目的:采用高脂高能量饮食诱导大鼠制备非酒精性脂肪性肝病(NAFLD)模型,给予饮食干预治疗,观察大鼠血清生化指标及肝脏组织病理病变,初步探讨胰岛素及其相关信号通路因子胰岛素受体(INSR)、胰岛素受体底物l(IRS-l)在NAFLD发病机制中的作用和饮食干预的影响。 方法:将40只雄性Sprague-Dawley大鼠随机分为5组,分别为8周正常饮食组(NC1组),8周高脂饮食组(HFD1组),16周正常饮食组(NC2组),16周高脂饮食组(HFD2组)和饮食干预组(DIET组 ...
崔帆
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Gut microbiota dynamics of adult and sub‐adult sika deer during reintroduction 重引入过程中成年和亚成年梅花鹿肠道微生物的动态变化

open access: yesIntegrative Conservation, Volume 3, Issue 3, Page 257-270, September 2024.
Natural training enclosure design schematic. We selected 12 sika deer including six adults and six sub‐adults. Key considerations in the design of the natural training were to divide the training spatial ground into two parts (30 × 30 m small areas for isolation of new individuals and large areas measuring 200 × 600 m for free walking), and the ...
Wentao Zhang   +10 more
wiley   +1 more source

凡纳滨对虾(Litopenaeus vannamei)不同产卵频次雌虾卵巢比较代谢组学分析

open access: yesHaiyang yu huzhao
为探究凡纳滨对虾(Litopenaeus vannamei)雌虾产卵频次差异的分子机制,以多次产卵和不产卵凡纳滨对虾雌虾作为研究对象,采用液相色谱与质谱联用(LC-MS)非靶向代谢组学技术对成熟发育早期和晚期的雌虾卵巢进行内源性代谢物分析。结果显示,卵巢成熟发育早期,检测到156种差异代谢物,主要包括胆固醇、雄烯二酮、磷脂酰胆碱(PC)、二十二碳六烯酸(DHA)、前列腺素E2等脂类相关代谢产物,以及精氨酸、苯丙氨酸、丝氨酸、缬氨酸、亮氨酸等氨基酸,富集在128条代谢通路中,如卵巢类固醇生成 ...
张 硕   +11 more
doaj   +1 more source

A Preliminary Study On Activating AMPK By MED [PDF]

open access: yes, 2010
依赖于5’-AMP激活的蛋白激酶——AMPK在保持细胞微环境的能量稳态上扮演了至关重要的角色,能够被细胞内AMP的增多和ATP的减少所激活,作为代谢感受器调节细胞内ATP相关的代谢途径。AMPK除了调节糖代谢,脂代谢,蛋白质合成等很多能量相关的物质代谢途径外,还在细胞凋亡和血管生成途径中起到重要调节作用。如果能量代谢失衡,则会引起代谢综合症等多种疾病,严重影响现代人的生活,威胁人的健康。作为能量代谢过程中的关键酶,AMPK可以作为代谢综合症的治疗靶点。 AMPK不仅能够被细胞内AMP ...
杨梅
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利培酮合并舒眠胶囊治疗精神分裂症的疗效及对患者糖、脂代谢的影响 [PDF]

open access: yes
Objective: To explore the curative effect and influence on glucose and lipid metabolism of risperidone with Shu Mian capsules in patients with schizophrenia .Methods: 128patients with chronic schizophrenia were randomly divided into the combined group ...
Fan, Xin-yin   +5 more
core   +2 more sources

2型糖尿病脂质代谢与血糖关系

open access: yesZhongguo shiyan zhenduanxue, 2002
目的 了解 2型糖尿病 (ⅡDM)患者血脂代谢状况 ,以及血糖控制对血脂代谢的影响 ,为糖尿病患者血脂代谢异常选择治疗时机提供理论依据。方法 对 5 2例ⅡDM患者在血糖控制前后分别进行血糖、血脂检测 ,并与 4 0例健康人的血糖、血脂进行对比分析。结果 ⅡDM患者TCH、TG、LDL C及ApoB升高 ,HDL CApoAI降低 (P
池莲祥   +5 more
doaj  

脂质代谢组与卒中的因果关系:系统孟德尔随机化研究Causal Relationship between Lipid Metabolome and Stroke: A Systematic Mendelian Randomization Study

open access: yesZhongguo cuzhong zazhi
目的 脂质代谢异常与卒中的发生发展密切相关。本研究旨在探究脂质代谢组与卒中及其亚型的因果关联,解析脂蛋白成分对卒中的影响。 方法 基于213种脂质代谢指标以及全因卒中(any stroke,AS)、全因缺血性卒中(any ischemic stroke,AIS)及其3种亚型——大动脉型卒中(large artery stroke,LAS)、心源性栓塞型卒中(cardioembolic stroke,CES)和小血管型卒中(small vessel stroke,SVS)的GWAS ...
姜明慧,许喆,石延枫,张杰,李昊,程丝 (JIANG Minghui, XU Zhe, SHI Yanfeng, ZHANG Jie, LI Hao, CHENG Si )
doaj   +1 more source

有机磷酸酯在环境/ 生物相中的分布、分析方法及毒理效应 [PDF]

open access: yes, 2016
有机磷酸酯(organophosphate esters, OPEs)主要作为阻燃剂及增塑剂等而被广泛使用,且极易释放于环境。近年来,由于溴系阻燃剂的禁用,有机磷酸酯类阻燃剂的产量及消费量大幅增加,OPEs 已经成为一种新兴污染物并受到广泛关注,多篇文献报道了其在环境及生物相中的分布和毒理效应。本文主要对OPEs 在地表水、沉积物、大气及生物相中的分布、分析方法及毒理效应进行综述,并对未来OPEs 分布及毒理学研究进行展望 ...
李斐   +1 more
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