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人脐带间充质干细胞分离扩增方法的优化

Zhongshan Daxue xuebao. Yixue kexue ban, 2011
【目的】 探究一种高效稳定分离、扩增人脐带间充质干细胞（hUC-MSCs）的方法。【方法】取材脐带20条，获得Wharton’s Jelly组织，分别用酶联合消化法（12例）和酶序贯消化法（8例）来分离、提取hUC-MSCs，比较两种方法分离hUC-MSCs的成功率、原代培养时间及获得的细胞数量；利用低糖DMEM（LG-DMEM）完全培养基和LD-Mesen培养基（MesenPro RSTM与LG-DMEM的混合培养基）分别培养hUC-MSCs，比较两种培养体系的扩增效率 ...
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Human umbilical cord mesenchymal stem cells attenuate diabetic nephropathy through the IGF1R-CHK2-p53 signalling axis in male rats with type 2 diabetes mellitus. [PDF]

J Zhejiang Univ Sci B
Zhang H, Wang X, Hu B, Li P, Abuduaini Y, Zhao H, Jieensihan A, Chen X, Wang S, Guo N, Yuan J, Li Y, Li L, Yang Y, Liu Z, Tang Z, Wang H.   +16 more
europepmc   +1 more source

[Successful treatment of a hepatitis B-related acute-on-chronic liver failure patient with adefovir dipivoxil combined with artificial liver and human umbilical mesenchymal stem cells]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Niu JJ, Wang F, Xin YN, Chen LZ.
europepmc   +1 more source

[Single non-blood-related umbilical cord blood transplantation using a reduced-intensity conditioning regimen for the treatment of severe aplastic anemia]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Wu Y, Tang BL, Song KD, Sun GY, Pan TZ, Huang AJ, Yan BB, Zhu XY.   +7 more
europepmc   +1 more source

[Effects of applying human umbilical cord mesenchymal stem cell exosomes through different pathways to treat full-thickness skin defect wounds in mice]. [PDF]

Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi
Wang HY, Ba T, Zhou B, Yan ZQ, Wang RJ, Liu LY.   +5 more
europepmc   +1 more source

[Human umbilical cord mesenchymal stem cells differentiate into neuron-like cells after induction with B27-supplemented serum-free medium]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao, 2020
Li Y, Yang J, Fu G, Zhou P, Liu Y, Li Z, Jiao G.   +6 more
europepmc   +1 more source

[Haploidentical donor peripheral blood stem cell transplantation using third-party cord blood compared with matched unrelated donor transplantation for patients with hematologic malignancies]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Ma X, Chen Y, Liu Y, Cheng TT, Chen X, Zeng C, Hua J, Wang SY, Xu YJ.   +8 more
europepmc   +1 more source

[Human umbilical cord mesenchymal stem cell-derived exosomes alleviate pulmonary fibrosis in mice by inhibiting epithelial-mesenchymal transition]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao, 2020
Yang J, Hu H, Zhang S, Jiang L, Cheng Y, Xie H, Wang X, Jiang J, Wang H, Zhang Q.   +9 more
europepmc   +1 more source

[Effects of gelatin methacrylate anhydride hydrogel loaded with small extracellular vesicles derived from human umbilical cord mesenchymal stem cells in the treatment of full-thickness skin defect wounds in mice]. [PDF]

Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi
Chen YQ, Zhou YQ, Wei Q, Xie XY, Liu XZ, Li DW, Shen ZA.   +6 more
europepmc   +1 more source

[Mechanisms and clinical research progress of mesenchymal stromal cell therapy for steroid-refractory acute graft-versus-host disease]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Wang N, Xu ZL, Liu DH.
europepmc   +1 more source