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环磷酰胺预处理脐血移植小鼠模型的建立及其对骨髓龛位的影响 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2002 【目的】建立环磷酰胺(CTX)预处理脐血移植(UCBT)小鼠模型, 并探讨预处理后骨髓龛位腾出的特点和机制。 【方法】分别以100 , 200 , 380 mg/ kg 3 种剂量CTX 腹腔注射BALB/ c 小鼠, 检测注射后1 周内外周血象、骨髓及外周血CD34 + 细胞含量、骨髓细胞凋亡及病理学改变。用C57BL/6 鼠脐血(FNPB)作供体移植经“ 致死量”CTX 预处理的BALB/ c 鼠, 动态 观察移植后受鼠存活状况、植入水平、造血与免疫功能恢复及移植物抗宿主病(GVHD)情况 ...
徐宏贵, 黄文革
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Zhongshan Daxue xuebao. Yixue kexue ban, 1996 应用彩色连续波超声多普勒血流分析仪对３１２例孕晚期孕妇共进行３６３次脐血流检查，２９例胎儿宫内生长迟缓（ＩＵＧＲ）者脐血流Ｓ／Ｄ比值（３．５８±１．１６）、ＰＩ（脉动指数，１．１７±０．２９）、ＲＩ（阻力指教，０．７３±０．１８）较正常组（分别为Ｓ／Ｄ比值２．６８±０．７６、ＰＩ０．９２±０．２２、ＲＩ０．６０±０．０９）明显增高（Ｐ＜０．０１）；ＦＢＶＲ（快速血流量比，０．５１±０．０６）较正常组（０．５７±０．０５）明显降低（Ｐ＜０．０００５）。这些变化可能与胎儿心脏射血功能下降和 ...
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Comparative analysis of 2‐year outcomes in GRIT and TRUFFLE trials
Ultrasound in Obstetrics &Gynecology, Volume 55, Issue 1, Page 68-74, January 2020., 2020 ABSTRACT Objective To explore the effect on perinatal outcome of different fetal monitoring strategies for early‐onset fetal growth restriction (FGR). Methods This was a cohort analysis of individual participant data from two European multicenter trials of fetal monitoring methods for FGR: the Growth Restriction Intervention Study (GRIT) and the Trial ...
W. Ganzevoort +164 more
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Zhongshan Daxue xuebao. Yixue kexue ban, 2008 【目的】 腰硬联合麻醉(CSEA)下行剖宫产时产妇易发生低血压,导致胎盘低灌注产生缺血缺氧危及胎儿，本文旨在观察静注小剂量磷酸肌酸钠对剖宫产胎儿血糖及血气的影响,探讨提高剖宫产手术胎儿安全性的方法。【方法】 择期剖宫产产妇60例, ASA Ⅰ～Ⅱ 级,随机分为实验组(磷酸肌酸钠 1 g/20 mL,麻醉前10 min静注)和对照组(NS 20 mL,麻醉前10 min静注),每组均为30例?CSEA穿刺针经L2-3行蛛网膜下腔穿刺成功后注入0.75%布比卡因1.0 ～ l.2 mL ...
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高渗氯化钠羟乙基淀粉40对产妇腰麻后低血压及新生儿早期安全的影响
Zhongshan Daxue xuebao. Yixue kexue ban, 2012 【目的】 探讨预注高渗氯化钠羟乙基淀粉注射液40(HSH40)对腰麻后产妇低血压及新生儿的影响?【方法】 60例拟行择期剖宫产的足月产妇,ASA I-II 级,随机分为HSH40组(n = 30)和乳酸钠林格氏液(RL)组(n = 30)?在腰麻前15 ~ 20 min内,HSH40组静脉注射250 mL HSH40,RL组静脉注射500 mL RL?腰麻穿刺点在腰3/4椎间隙,注入的腰麻药为0.5% 布比卡因2 mL?观察腰麻后15 min内低血压的发生情况,并对新生儿进行Apgar评分 ...
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Zhongguo shiyan zhenduanxue, 2021 目的研究双胎脐血流监测及胎心监护监测对高危妊娠产妇的预测价值。方法选取2017年5月至2020年5月间石家庄市第六医院产科收治的80例双胎高危妊娠产妇为研究对象,按照产前产妇脐动脉血流监测结果及临产过程胎心监测结果分为四组:A组:脐动脉S/D值及胎心率均正常,42例;B组:脐动脉S/D值正常,胎心率异常,9例;C组:脐动脉S/D值异常,胎心率正常,12例;D组:胎心率、脐动脉S/D值均异常,17例,对产妇进行脐血流监测及胎心监护监测,观察记录产妇剖宫产、脐带绕颈、羊水污染、胎儿窘迫 ...
武菁菁 +4 more
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干血滤纸片DNA分析新生儿CYP21基因和SRY基因方法初探
Zhongshan Daxue xuebao. Yixue kexue ban, 2008 【目的】 初步探讨干血滤纸片DNA分析新生儿CYP21基因和SRY基因的方法? 【方法】 采用chelex-100提取20例新生儿的干血滤纸片DNA,采用一步法PCR扩增CYP21基因Exon1-3片段,与脐带血DNA的结果进行比较?同时检测了11例男性新生儿样本的SRY基因? 【结果】 应用干血滤纸片DNA模板,一步法PCR扩增CYP21基因的扩增效率为10%(2/20),脐带血的扩增结果为100%?SRY基因的扩增效率为100%(11/11)?
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Ultrasound in Obstetrics &Gynecology, Volume 66, Issue 1, Page 41-50, July 2025.ABSTRACT Objectives Monochorionic diamniotic (MCDA) twins with selective fetal growth restriction (sFGR) and either continuous (cAREDF) or intermittent (iAREDF) absent or reversed end‐diastolic flow in the umbilical artery face significant fetal and neonatal risks.
A. T. R. Noll +19 more
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Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 6, Page 749-760, June 2025.ABSTRACT Objective Placental dysfunction can result in small‐for‐gestational age (SGA) or fetal growth restriction (FGR). The aim of this prospective cohort study was to assess the association of the cerebroplacental ratio (CPR) and other more conventional fetoplacental Doppler indices, circulating placental growth factor (PlGF) levels and soluble fms ...
J. Hong +6 more
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Prenatal diagnosis and postnatal outcome of Type‐III vasa previa: systematic review of literature
Ultrasound in Obstetrics &Gynecology, Volume 63, Issue 1, Page 24-33, January 2024.ABSTRACT Objective Type‐III vasa previa (VP) is a rare form of VP, not necessarily associated with other placental or vascular anomalies, in which aberrant vessels run from the placenta to the amniotic membranes, near the internal cervical os, before returning to the placenta. Early diagnosis of Type‐III VP is important but technically challenging. The
M. Pozzoni +7 more
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