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N-乙酰半胱氨酸在缺血性脑卒中的作用及机制

Zhongshan Daxue xuebao. Yixue kexue ban
缺血性脑卒中（CIS）是指因脑部血液循环障碍，缺血、缺氧所致的局限性脑组织的缺血性坏死或软化，其发病率在脑血管病中占据首位。氧气和营养供应的减少会导致神经元的严重丧失，并导致中风患者脑功能的缺陷。开发缺血性脑卒中的治疗方法仍然是临床医学的重要挑战。抗氧化剂N-乙酰半胱氨酸（NAC）是谷胱甘肽前体物质，缺血性脑卒中动物模型及一些临床研究的证据表明，NAC可以有效地保护大脑免受缺血损伤。本文从抗氧化、抑制炎症、保护脑神经和线粒体功能、稳定动脉斑块及溶栓功能等多方面阐述NAC在CIS中的作用机制 ...
杨晨, 万文辉
doaj  

[Association analysis between genetic nurturing effects of <i>CTNNA</i> gene family and ischemic stroke]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Wu J, Zheng L, Yu H, Wang H, Xie S, Chen Y, Li T, Wang M, Qin X, Wu T, Chen D, Wu Y, Hu Y.   +12 more
europepmc   +1 more source

[An interpretable machine learning-based prediction model for risk of death for patients with ischemic stroke in intensive care unit]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao, 2023
Luo X, Cheng Y, Wu C, He J.
europepmc   +1 more source

[Efficacy and safety of intravenous thrombolysis in patients with mild acute ischemic stroke]. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban
Li X, Zhang X, Wang A, Wang T, Yan Y, Fu J, Zheng J, Lou M, Hu J.   +8 more
europepmc   +1 more source

[Efficacy of intravenous thrombolysis beyond 4.5 to 24 hours in patients with isolated posterior circulation acute ischemic stroke]. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban
Wang J, Yan S, Lang Y, Jin T, Tang H, Qian S, Yu H, Lou M, Chen H.   +8 more
europepmc   +1 more source

[Research progress on the mechanism and potential applications of gut microbiota-derived extracellular vesicles in ischemic stroke]. [PDF]

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
Xiao M, Li X, Li J, Wu M, Zhu L.
europepmc   +1 more source

[Research on the effect of multi-modal transcranial direct current stimulation on stroke based on electroencephalogram]. [PDF]

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi, 2022
Yu H, Zhang S, Wang C, Guo L, Xu G.
europepmc   +1 more source

[Association between dynamic elevation of high-sensitivity cardiac troponin T and functional outcomes in patients with acute ischemic stroke]. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban
Xi Z, Hu H, Huang X, Gao Y, Wu F, Jin X, Zhu X, He Y, He Y, Mao L.   +9 more
europepmc   +1 more source

[Advances in stroke after transcatheter aortic valve replacement]. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban
Zhou Y, Yang R.
europepmc   +1 more source

[Research progress on intelligent assessment system for upper limb function of stroke patients]. [PDF]

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi, 2022
Li S, Wu K, Meng Q, Yu H.
europepmc   +1 more source