Results 11 to 20 of about 64,536 (152)
Zhongguo cuzhong zazhi, 2023 脑出血是一种由脑实质血管破裂引起的严重疾病，目前尚无有效的治疗方法。研究表明炎症反应在脑出血继发性脑损伤中发挥了重要作用。在出血部位，小胶质细胞被迅速招募并激活，且在促炎型与抑炎型之间动态转变，不同的信号通路可以改变小胶质细胞极化的状态，从而对脑损伤起到调控作用，这提示了小胶质细胞在脑出血继发脑损伤的病理过程中具有复杂的作用机制。促炎型小胶质细胞释放的各种炎症因子介导神经细胞和神经组织的炎症损伤；抑炎型小胶质细胞释放趋化因子、脑源性神经营养因子、抗炎介质等诱导小胶质细胞向病变方向迁移 ...
孔德敏1，邹伟2
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Zhongshan Daxue xuebao. Yixue kexue ban, 2021 炎症和免疫是脑血管病病理生理的重要部分，其动态变化影响着脑血管病的进程和预后。缺血性卒中急性期的炎症激活造成大脑病灶的炎症损伤，还参与衰老相关的脑小血管病的脑损害，引起血管性痴呆等认知功能障碍。本文就炎症和免疫与脑血管病相互作用机制的研究进展进行综述，以更好地了解和探索免疫调节在治疗中的潜力。
陆正齐
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Zhongshan Daxue xuebao. Yixue kexue ban, 2008 【目的】 探讨吞咽功能的评估对脑卒中患者发生吸入性肺炎的影响65377;【方法】 对286例脑卒中患者随机分为实验组172例和对照组112例,实验组采用床边吞水试验评估病人的吞咽功能并根据吞咽功能评估结果采取预见性护理干预措施65377;【结果】 实验组没有发生吸入性肺炎,对照组发生吸入性肺炎4例,吸入性肺炎的发生率为3.6%,实验组吸入性肺炎的发生率明显低于对照组(P < 0.05)65377;【结论】 对脑卒中病人进行吞咽功能的评估,能及早进行护理干预,减少患者发生吸入性肺炎 ...
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Zhongshan Daxue xuebao. Yixue kexue ban, 2016 摘 要: 【目的】 分析抗真菌药物联合脑室-腹腔分流术对伴有明显颅内高压新型隐球菌性脑膜炎的治疗效果?【方法】 20例确诊为新型隐球菌性脑膜炎并伴有明显颅内高压的患者,在抗真菌药物治疗的基础上实施了脑室-腹腔分流术,通过分析比较脑室-腹腔分流术前后颅内压力?隐球菌数量及主要临床症状的变化,并观察手术后并发症发生情况,评价抗真菌药物联合脑室-腹腔分流术对伴有明显颅内高压新型隐球菌性脑膜炎的治疗效果?
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Zhongshan Daxue xuebao. Yixue kexue ban, 1996 选择疱疹病毒科病毒ＤＮＡ多聚酶基因高保守区中的一对引物，一次ＰＣＲ可同时扩增疱疹病毒科的４种病毒［单纯疱疹病毒Ｉ型（ＨＳＶ１）、单纯疱疹病毒Ｉ型（ＨＳＶ２）、ＥＢ病毒（ＥＢＶ）、及巨细胞病毒（ＣＭＶ）］相应的ＤＮＡ片段。根据扩增产物分子的大小及对扩增产物酶切分析，可将标本中的４种病毒准确分型。用该法检测临床疑为病毒脑炎患者和其他中枢神经系统疾病患者（对照组）的脑脊液（ＣＳＦ），脑炎组ＣＳＦ阳性率３０％（９／３０），对照组ＣＳＦ阳性率６．７％（２／３０）；其中８例为ＨＳＶ１阳性，２例为ＣＭＶ阳性 ...
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Mechanisms of bariatric surgery for weight loss and diabetes remission 减重手术减轻体重和缓解糖尿病的机制
Journal of Diabetes, Volume 15, Issue 9, Page 736-752, September 2023., 2023 Highlights Controversial changes in intestinal hormones after bariatric surgery (BS) were summarized. The changes of signaling proteins involved in insulin resistance and the newly proposed changes in growth differentiation factor 15, exosomes, and extracellular vesicles after BS were elucidated.
Mengsha Yin +6 more
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The Association of Retinal age gap with metabolic syndrome and inflammation 视网膜年龄差与代谢综合征和炎症的关系
Journal of Diabetes, Volume 15, Issue 3, Page 237-245, March 2023., 2023 Highlights Retinal age gap is a non‐invasive and cost‐effective aging biomarker. Retinal age gap was significantly associated with metabolic syndrome and inflammation. Retinal age gap could be potentially used as a screening tool for metabolic syndrome in large populations.
Zhuoting Zhu +13 more
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Journal of Diabetes, Volume 14, Issue 12, Page 806-814, December 2022., 2022 Highlights Metformin activates GDF15 expression, which reduces appetite with induction of weight loss in both diabetic and non‐diabetic patients. GDF15 level is linked and correlated with the progression of diabetic complications including thrombosis, diabetic nephropathy, diabetic neuropathy, and diabetic retinopathy. Abstract Type 2 diabetes mellitus
Hayder M. Al‐kuraishy +8 more
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Wireless Communications and Mobile Computing, Volume 2021, Issue 1, 2021., 2021 Clinical named entity recognition (CNER) identifies entities from unstructured medical records and classifies them into predefined categories. It is of great significance for follow‐up clinical studies. Most of the existing CNER methods fail to give enough thought to Chinese radical‐level characteristics and the specialty of the Chinese field.
Yue Wu +6 more
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