Zhongshan Daxue xuebao. Yixue kexue ban, 2010 【目的】 分析同一组脑胶质瘤的MRI灌注和扩散加权图像信息,对比这两种功能成像对脑胶质瘤病理分级的诊断价值65377;【方法】 42例(低级胶质瘤20例,高级胶质瘤22例)脑胶质瘤患者行MRI灌注及扩散加权成像,测量肿瘤实质的灌注参数和弥散参数,进行差异的t检验,采用受试者操作特征曲线(ROC曲线)确定找到诊断阈值,计算敏感性及特异性65377;对两种诊断方法进行评价并对诊断符合率进行χ2检验65377;【结果】 低级胶质瘤20例,高级胶质瘤22例65377;低级胶质瘤的rCBV,rMSD,rMTT ...
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[Establishment of an Engineered Bacterial Membrane Biomimetic Nanodrug Delivery System and Its Role in the Treatment of Glioma]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanZhao Y +9 more
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[A predictive model for survival outcomes of glioma patients based on multi-parametric, multi-regional MRI radiomics features and clinical features]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoHuang X, Chen F, Zhang Y, Liang S.
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[Fully Automatic Glioma Segmentation Algorithm of Magnetic Resonance Imaging Based on 3D-UNet With More Global Contextual Feature Extraction: An Improvement on Insufficient Extraction of Global Features]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanTian H, Wang Y, Ji Y, Rahman MM.
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[Predicting cerebral glioma enhancement pattern using a machine learning-based magnetic resonance imaging radiomics model]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoHe H +7 more
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Zhongguo shiyan zhenduanxue神经胶质瘤是最常见和最致命的脑肿瘤之一。手术切除后放疗加化疗是目前神经胶质瘤患者的主要治疗手段。然而，由于胶质瘤细胞对基因毒性治疗的耐药性，以及肿瘤的异质性的本质，极大地限制了胶质瘤治疗的疗效。本文从癌症干细胞、细胞凋亡逃逸和代谢重编程等角度，阐述了促进神经胶质瘤替莫唑胺耐药的相关机制，为神经胶质瘤的靶向治疗提供新的研究思路和策略。
齐方明 +4 more
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[circ_EPHB4 synergizes with YTHDF3 to promote glioma progression <i>via</i> m<sup>6</sup>A-dependent stabilization of Wnt3]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoJin C, Liu J, Liu B, Fei X, Liao Y.
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Zhongshan Daxue xuebao. Yixue kexue ban, 1998 目的: 比较替尼泊甙(VM26)和卡氮芥( BCNU)分别联合口服环己亚硝脲( CCNU)治疗脑胶质瘤的疗效。方法: 对 27 例脑胶质瘤手术切除后, 采用微导管进行超选择脑动脉灌注法分组灌注 VM26(A 组)和 BCNU( B 组) ,并且两者联合口 服 CCNU, 化疗后,依肿瘤实际体积的变化和平均生存时间观察疗效。结果: A 组有效率 12/15, B 组有效率 4/12,A 组和 B 组 平均生存时间分别为 25. 3 个月和 21. 1 个月(P
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[Therapeutic potential of extracellular vesicles in neurological diseases]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoDU Q, Yang C, Xia X, Wang T.
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[Sulforaphane reduces reactive astrocyte-mediated neuron apoptosis <i>in vitro</i> by inhibiting the MAPK/NF-κB signaling pathway in Aβ42 oligomer-activated astrocytes]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoZhang S +5 more
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