Results 11 to 20 of about 3,789 (105)

The Association of Retinal age gap with metabolic syndrome and inflammation 视网膜年龄差与代谢综合征和炎症的关系

open access: yesJournal of Diabetes, Volume 15, Issue 3, Page 237-245, March 2023., 2023
Highlights Retinal age gap is a non‐invasive and cost‐effective aging biomarker. Retinal age gap was significantly associated with metabolic syndrome and inflammation. Retinal age gap could be potentially used as a screening tool for metabolic syndrome in large populations.
Zhuoting Zhu   +13 more
wiley   +1 more source

Comparison of open fetal, fetoscopic and postnatal surgical repair for open spina bifida: decision analysis

open access: yesUltrasound in Obstetrics &Gynecology, Volume 66, Issue 4, Page 433-442, October 2025.
ABSTRACT Objective Currently, there are several surgical approaches to manage fetal open spina bifida (OSB), namely postnatal surgical repair, open fetal surgery and its minimally invasive alternative, fetoscopic repair. Our objective was to determine the optimal surgical approach for OSB, weighing the benefits and risks to the fetus and the pregnant ...
Y. Kunpalin   +6 more
wiley   +1 more source

Placental biomarker and fetoplacental Doppler abnormalities are strongly associated with placental pathology in pregnancies with small‐for‐gestational‐age fetus: prospective study

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 6, Page 749-760, June 2025.
ABSTRACT Objective Placental dysfunction can result in small‐for‐gestational age (SGA) or fetal growth restriction (FGR). The aim of this prospective cohort study was to assess the association of the cerebroplacental ratio (CPR) and other more conventional fetoplacental Doppler indices, circulating placental growth factor (PlGF) levels and soluble fms ...
J. Hong   +6 more
wiley   +1 more source

Combating infections under siege: Healthcare challenges amidst the military assault in Gaza

open access: yesWorld Medical &Health Policy, Volume 17, Issue 1, Page 188-213, March 2025.
Abstract The ongoing Israeli military assault on Gaza has caused a devastating collapse of healthcare infrastructure, resulting in an unprecedented surge in infectious diseases. The destruction of sanitation systems, restrictions on medical supplies, and displacement of civilians have created an environment conducive to the rapid spread of waterborne ...
Bilal Irfan   +24 more
wiley   +1 more source

Topical and transdermal botanical formulations of the Chinese pharmacopoeia—A review

open access: yesPhytotherapy Research, Volume 38, Issue 9, Page 4716-4735, September 2024.
Abstract In pharmaceutics, ingredients are classified as active ingredients and excipients. In topical/transdermal phytomedicines, an ingredient may serve both functions. Published information on these dual‐purpose ingredients and their pharmacological relevance is limited.
Jingyi Gu   +3 more
wiley   +1 more source

外周血中性粒细胞/淋巴细胞比值在儿童细菌性脑膜炎和病毒性脑炎鉴别诊断中的应用

open access: yesZhongguo shiyan zhenduanxue, 2019
脑炎/脑膜炎是指各种病原体,包括细菌、病毒和螺旋体等侵犯脑部或脊髓引起的急性炎症,主要症状表现有发热、头痛和颈项强直等[1]。根据引发脑炎病原体的不同,脑炎/脑膜炎主要分为细菌性和病毒性感染两种。据Hasbun[2]等的研究,引发中枢神经系统感染的主要病原有肠病毒(51.6%)、细菌(14.1%)和单纯疱疹病毒(8.3%)等 ...
刘秀红   +4 more
doaj  

隐球菌性脑炎患者颗粒酶B、颗粒溶素、穿孔素的表达及临床意义

open access: yesZhongguo shiyan zhenduanxue, 2010
目的研究颗粒酶B(granzymeB,GrB)、颗粒溶素(granulysin,GNLY)及穿孔素(perforin,又称pore-forming pro-tein,PFP)三种免疫效应分子在隐球菌性脑膜炎(cryptococcal meningitis)外周血单个核细胞中的表达及其临床意义。方法首先用密度梯度离心法分离得到25例隐球菌性脑膜炎患者和30例健康人外周血单个核细胞(peripheral blood mononuclear cells,PBMC),其次用免疫印迹(westernblot ...
周晔   +6 more
doaj  

TRAIL及其受体与隐球菌性脑膜炎的关联性研究

open access: yesZhongguo shiyan zhenduanxue, 2008
目的研究建立实时荧光定量(RFQ)-PCR法测定TRAIL及其受体DcR1、DcR2、DR4、DR5 mRNA含量的方法,探讨其在隐球菌性脑膜炎患者外周血单个核细胞中表达的检测价值,并分析隐球菌性脑膜炎患者细胞因子与TRAIL及其受体的相关性。方法设计特异性的引物和探针,以人基因GAPDH为内参照,用实时定量PCR的方法检测35例健康人和35例隐球菌性脑膜炎患者外周血单个核细胞中TRAIL及其受体mRNA的表达水平,采用ELISA方法检测血清IL-4、IL-10、TNF-α、IFN-γ浓度 ...
周晔   +7 more
doaj  

血清降钙素原、C-反应蛋白、白介素-6联合检测对中枢神经系统感染的诊断意义

open access: yesZhongguo shiyan zhenduanxue, 2012
化脓性脑膜炎与病毒性脑膜炎是两种中枢神经系统感染性疾病,由于二者临床表现缺乏特异性,以及近年来抗生素的泛用使其脑脊液的改变趋于不典型造成,二者的鉴别存在一定难度,从而延误诊治,常导致脑损伤的发生。化脑患者和病脑患者降钙素原水平存在差异 ...
孙兴元, 石寒冰, 赵焕
doaj  

累及胼胝体压部的脑炎的临床特点与影像学特征研究

open access: yesZhongguo shiyan zhenduanxue, 2011
累及胼胝体压部的脑膜脑炎非常少见,临床表现缺乏特异性,现报告我院4例累及胼胝体压部的脑膜脑炎患者的临床特点和影像学特征并探讨其发病机理,以提高对本病的诊断和认识水平。1资料与方法1.1一般资料2007-2010年住院患者4例,年龄分别为:37,35,25,和22岁,2例女性,2例男性 ...
张艳红   +4 more
doaj  

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