UVA Assisted 4-Thiothymidine for Cancer Treatment [PDF]
, 2016 This article reviews the developments of 4-thiothymidine analogues, assisted with UVA light, as a novel cancer therapy. First, the key points on synthetic chemistry, photochemistry and cellular toxicity of 4-thiothymidine are summarized.
Feng, Luo +3 more
core +1 more source
The Functions and Mechanisms of Histone Demethylase JMJD1A in Urinary Bladder Cancer Development [PDF]
, 2015 JMJD1A（JumonjiCdomain-containing1A），又名JHDM2A，KDM3A，是一种组蛋白去甲基化酶，可以特异性去除H3K9位点的一甲基化和二甲基化，在组蛋白甲基化修饰中起到重要作用。JMJD1A表达受到低氧诱导因子HIF-1α（hypoxia-induciblefactor1α）的调节，并且参与到肿瘤细胞对低氧环境的适应性调节过程中。 膀胱癌是世界范围内高发和高致死率的恶性肿瘤之一。已有报道JMJD1A在膀胱癌肿瘤组织中高表达，但是JMJD1A在膀胱癌的发生发展机制尚不清楚 ...
秦丽萍
core
Clinical evaluation of urinary basic fetoprotein and the BTA test for detection of bladder cancer [PDF]
, 2000 1)Tl以下の膀胱癌の診断に尿中BFPは尿細胞診より有用と考えられた.2)尿中BFPを尿細胞診と併用することは, Tl以下及びG2以下の膀胱癌の診断に有用である.3)BTA試験を尿中BFP及び尿細胞診と併用することは, Tl以下及びG2以下の膀胱癌の診断に有用な可能性がある.4)尿中BFPは, 膿尿及び尿路変向施行により偽陽性を示すと考えられた.5)BTA試験は, 膿尿で偽陽性を示す可能性があり, また尿路変向施行により偽陽性を示すと考えられたWe compared the results of ...
井上, 幸治 +5 more
core
Occupational cancer of the urinary bladder: the diagnostic value of urinary cytology in dyestuff workers exposed to aromatic amines [PDF]
, 1989 A total of 90 dyestuff workers who were engaged in the production of aromatic amines during the post-war period after the 2nd world war have been examined since 1967 by exfoliative cytologic examination.
松島, 正浩
core
Research on Mechanisms of Urinary Bladder Mesenchymal Stem Cells Promote Cell Growth and Migration of Urothelial Carcinoma Cells Line 5637 [PDF]
, 2015 目的：初步研究膀胱间充质干细胞促进膀胱癌生长及迁移的机制。方法：1.体外分离、培养并鉴定膀胱间充质干细胞；2.在体外实验中，以WST-1测定膀胱间充质干细胞培养上清液对于膀胱癌细胞生长的影响，并以划痕实验测定膀胱间充质干细胞培养上清液对于膀胱癌细胞迁移能力的影响；3.在动物模型中测定膀胱间充质干细胞对于膀胱癌细胞生长和迁移能力的影响；4.以WESTERN-BLOT检测相关信号通路关键蛋白表达的变化以研究膀胱间充质干细胞促进膀胱癌生长及迁移的机制：结果：1.膀胱间充质干细胞表达CD105 ...
佟智超
core
A clinical study of superficial bladder cancer with grade 3 components [PDF]
, 1998 1986年1月からの10年間に治療されたgrade 3成分を含む表在性膀胱癌患者33例についてretrospectiveに検討した. 1)33例中3例は膀胱癌以外の疾患で死亡し, 6例が膀胱癌にて死亡した.2年生存率は83%, 5年生存率は75%, 平均観察期間は50ヵ月であった. 2)単変量解析では腫瘍形態と腫瘍の大きさが有意な予後判定因子であったA retrospective study was done on 33 patients treated for superficial bladder ...
上山, 裕 +9 more
core
Epidermal growth factor in the urine of patients with renal cell carcinoma and bladder tumor [PDF]
, 1991 1)対照群43人の尿中EGF排泄量(平均値±SD)は, 11.7±7.0 ng/mg・creatinine (CRNN)であり, EGF排泄量と年齢との間に有意な負の相関があった.EGF排泄量は男性対照群で9.9±6.0 ng/mg・CRNN, 女性対照群で16.3±7.6 ng/mg・CRNNであった.2)腎癌患者14例の尿中EGF排泄量は, 15.9±12.0 ng/mg・CRNN, 年齢・性を合致させた対照群のそれは14.5±7.9 ng/mg・CRNNであった.3 ...
丹治, 進 +8 more
core
膀胱癌患者用QOL調査票FACT-BL(Functional Assessment of Cancer Therapy-Bladder)の日本語版作成とそれに基づく膀胱癌患者のQOL調査 [PDF]
, 1999 筑波大学University of Tsukuba博士（医学）Doctor of Philosophy in Medical Sciences1998【要旨 ...
107674, 樋之津, 淳子
core
A case of complete response in a patient with invasive bladder cancer due to intermittent intraarterial infusion chemotherapy using the alteration of blood flow [PDF]
, 1993 The patient was a 70-year-old male with invasive bladder cancer. We performed intermittent arterial infusion (ITI) combined with alteration of blood flow in the bladder wall using the contralateral arterial embolization.
仲谷, 達也 +6 more
core
Aurora-A/STK15/BTAK overexpression induces centrosome amplification, chromosomal instability, and transformation in human urothelial cells [PDF]
, 2007 Aurora-A/STK15/BTAK kinase encoding gene, located on chromosome 20q13, is frequently amplified and overexpressed in human cancers. Sen et al. previously demonstrated that Aurora-A amplification and overexpression are associated with aneuploidy and ...
Anand S, Penrhyn-Lowe S and Venkita +13 more
core +1 more source