Results 11 to 20 of about 1,373 (148)
膀胱癌是泌尿系统最常见的肿瘤之一,当前膀胱镜检查加病理活检是确诊和随访观察治疗后肿瘤复发进展的金标准,但该检查技术有创且存在有时因尿道狭窄、肿瘤出血致视野不清、取材不充分而影响判断等缺点。因此开发能媲美于膀胱镜检查的无创诊断方法一直是研究者们关注的热点。本文通过文献检索分析归纳总结近10年关于膀胱癌尿液无创诊断研究现状,并简要介绍本团队在该领域的相关研究进展。
陈炜
doaj +2 more sources
浅表性和浸润性膀胱癌微环境中树突状细胞的变化及意义 [PDF]
【目的】研究树突状细胞(Dc)在不同类型膀胱移行细胞癌及癌旁组织中的变化以及与肿瘤病理分级的关系,探讨恶性肿瘤免疫逃避的可能机制。【方法】将133例膀胱移行细胞癌病理标本按WHO标准进行病理分级,按1987年国际抗癌协会(UICC)标准进行临床分型(浅表和浸润),应用免疫组化法检测病理标本中Dc。【结果】133例标本中肿瘤Dc数目明显少于瘤旁组织(G1 16.85±1.1,G2 9.45±2.17,G3 2.99±1.19 vs G1 21.8±4.78,G2 21.71±4.72,G320.00±5 ...
丘少鹏 +3 more
doaj +2 more sources
PD-1/PD-L1在膀胱癌患者外周血T细胞和肿瘤细胞表达 [PDF]
【目的】探讨PD-1/PD-L1在膀胱肿瘤患者外周血T细胞和膀胱肿瘤细胞上表达的特点及临床意义。【方法】选 取我科收治的64例原发性膀胱癌患者作为实验组(浅表性46例,浸润性18例),对照组为正常人群,共15例。分别取外周 血,通过流式细胞仪检测CD8 + T淋巴细胞表明PD-1的表达量;另外取肿瘤患者膀胱癌组织和正常人群的膀胱肿瘤行免疫组 化检测膀胱细胞或膀胱肿瘤细胞表面PD-L1的表达情况。【结果】膀胱癌患者外周血中CD8 + T淋巴细胞PD-1的表达量明 显高于对照组[(2.25 ± 0 ...
龙兆麟 +3 more
doaj +2 more sources
【目的】 探讨影响非肌层浸润性膀胱尿路上皮癌复发的相关因素及其处理对策65377;【方法】 回顾性分析我院2003年1月到2008年12月161例非肌层浸润性膀胱尿路上皮癌患者临床随访资料,所有病例行经尿道膀胱肿瘤电切术,据术后复发率分析影响复发相关因素65377;【结果】 161例中, 45例术后复发,术后的总复发率为27.95%65377;肿瘤分级为G265380;G3级患者较G1级患者复发率高;肿瘤分期为T1期患者较Ta期患者复发率高;肿瘤多发患者较肿瘤单发患者复发率高 ...
doaj +1 more source
目的: 探讨无创早期诊断膀胱癌的有效方法: 对膀胱癌患者进行尿液中膀胱肿瘤抗原( BTA)测定与分析。方法: 对 64 例膀胱癌及 28 例非膀胱癌患者的尿进行 BTA 测定及尿脱落细胞学检查, 比较这两种方法的敏感度、特异度、准确度、阳 性及阴性似然比。结果: BTA 测定的敏感度、准确度、特异度、阳性及阴性似然比分别为 90. 6%、89. 3%、90. 2%、8. 5 及 0. 1; 尿脱落细胞学检查这些指标分别为 46. 9%、92. 9%、60. 9%、6. 6 及 0.
doaj +2 more sources
Analysis of risk factors of recurrence in non-muscle invasive bladder cancer patients after initial transurethral resection of bladder tumor [PDF]
Background and purpose: The recurrence rate of non-muscle invasive bladder cancer (NMIBC) after transurethral resection of bladder tumor (TURBT) is high. There are few studies on the risk factors of recurrence in NMIBC patients after initial TURBT.
TANG Duocai, ZHOU Shukui, ZHANG Guiyin, LIU Lei, LIAO Hong
core +1 more source
Research progress in intravesical instillation for non-muscle invasive bladder cancer [PDF]
Bladder cancer is the most common malignant tumor of the urinary system, which seriously affects patients’ health and life. Transurethral resection of bladder tumor is the main treatment for non-muscle invasive bladder cancer (NMIBC), whereas high ...
Yang Haihong, Shang Panfeng, Liu Jianbing
core +1 more source
Research progress in the treatment of bladder cancer based on nanotechnology [PDF]
Bladder cancer is the most common malignant tumor in the urinary system. Currently, the clinical treatment options for bladder cancer mainly include surgery, chemotherapy, radiotherapy, immunotherapy, targeted therapy, photodynamic therapy, combination ...
CAO Xiangqian +5 more
core +1 more source
【目的】 对比分析腹膜外与经腹腔开放性根治性膀胱切除回肠膀胱术的临床应用效果?【方法】 回顾性分析83例肌层浸润性膀胱癌患者的临床资料?其中45例为经腹膜外入路行根治性膀胱切除回肠膀胱术(腹膜外组),38例为经腹腔入路(经腹腔组)?【结果】 腹膜外组平均手术时间240 min,平均出血量300 mL,术后肠道排气时间48.6 h,离床下地时间4.5 d,术后住院时间12.5 d,均明显低于经腹腔组,差异均有统计学意义(P 0.05)?
doaj +1 more source
The value of VI-RADS combined with tumor contact length in the detection of muscle-invasive bladder cancer [PDF]
Background and purpose: The value of Vesical Imaging-Reporting and Data System (VI-RADS) based on multiparametric magnetic resonance imaging (MRI) in the preoperative assessment of bladder cancer muscle-invasive is increasingly recognized. However, there
CHEN Ruchuan, LIU Wei, ZHOU Bingni, LIU Xiaohang, ZHOU Liangping
core +1 more source

