Results 21 to 30 of about 1,373 (148)
Reactive Oxygen Species Affect the Tenderness of Bovine Muscle by Regulating Glycolysis during the Early Stage of Postmortem Cold Storage [PDF]
, 2023 This study was conducted to investigate the regulatory mechanism of reactive oxygen species (ROS) on the glycolysis pathway of bovine muscle and its impact on meat tenderness at the early stage of postmortem cold storage.
GUO Yuxuan, CHEN Cheng, SHI Xixiong, GUO Zhaobin, MA Guoyuan, ZHANG Yubin, ZHANG Li, YU Qunli
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Advances in basic research, clinical diagnosis and treatment of bladder cancer in 2022 [PDF]
, 2023 Bladder cancer (BCa) is a common malignant tumor of the urinary tract. Significant progress has been made in both basic and clinical research on BCa, which has further elucidated the drivers of BCa development at the gene and protein levels, and explored
ZHENG Shengfeng, ZHU Yiping, YE Dingwei
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Application status of cell models in clinical nutrition research [PDF]
, 2020 Traditional clinical nutrition research mostly stay at the stage of human and animal experiments. Cell model experiment has gradually become an important way in clinical nutrition research nowadays.
Jian HUANG +4 more
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AMP依赖的蛋白激酶及PI3K/Akt信号途径在颈动脉狭窄形成过程中的变化 [PDF]
, 2017 目的 观察AMP依赖的蛋白激酶（AMPK）及PI3K/Akt信号途径在颈动脉狭窄形成过程中的变化。方法 取SD大鼠经高脂喂养1个月后行颈总动脉球囊损伤术作为模型组（n=24）,继续喂养14 d后取损伤侧颈总动脉,行HE染色观测血管内皮损伤及内膜增生情况,应用荧光定量PCR法检测AMPK及PI3K/Akt mRNA水平,用Western印迹检测p-AMPK、PI3K、p-Akt蛋白水平,另取8只正常SD大鼠作为假手术组。结果 模型组大鼠血管内膜增生明显、管壁变厚;AMPK/PI3K/Akt ...
余文珍 +4 more
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UVA Assisted 4-Thiothymidine for Cancer Treatment [PDF]
, 2016 This article reviews the developments of 4-thiothymidine analogues, assisted with UVA light, as a novel cancer therapy. First, the key points on synthetic chemistry, photochemistry and cellular toxicity of 4-thiothymidine are summarized.
Feng, Luo +3 more
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Zhongguo shiyan zhenduanxue, 2021 近年来,全世界每年超过430 000名患者被诊断为膀胱癌[1]。膀胱癌患者往往年龄较大且病情复杂,超过一半的病例通常发生在75岁以上的人群中,泌尿外科医生常通过经尿道膀胱肿瘤切除术(TURBT)诊断、分期和治疗这种疾病。TURBT是治疗膀胱癌的主要手段,采用TURBT并非没有风险,当肿瘤位于膀胱侧壁或下壁时,TURBT期间产生的感应电流刺激靠近膀胱侧壁的闭孔神经,可导致突然和意外的内收肌痉挛,称为"闭孔神经反射",这种非预期的反射不仅导致外科医生在术中精神高度紧张,还增加了膀胱穿孔、感染、出血的可能 ...
幺雨含, 成双, 王琦, 李龙云
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Comparison of fluorescence in situ hybridization (FISH) and urine cytology in diagnosing urothelial carcinoma: a single-center retrospective cohort study [PDF]
Background and purpose: Urothelial carcinoma (UC) is a prevalent malignant tumor of the urinary system, and early diagnosis is crucial for improving patient prognosis.
WANG Zhiting, REN Min, XUE Tian, WANG Haochen, CHANG Heng, BAI Qianming, ZHOU Xiaoyan, ZHU Xiaoli
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尿细胞角蛋白19在膀胱移行细胞癌术后监测中的应用 [PDF]
, 2005 目的 评价尿细胞角蛋白19片段(CK19,又称CYFRA2 1 1)在膀胱移行细胞癌(BTCC)术后监测中的作用。方法 对67例保留膀胱的BTCC术后患者定期行膀胱镜检查发现2 1例复发,采用电化学发光免疫分析(ECLIA)技术测定复发组(2 1例)、未复发组(4 6例)和正常对照组(2 4例)的尿CKl9含量。结果 复发组尿CKl9的平均值为(19.60±18.5 7) μg/L ,明显高于未复发组(2 .3 3±1.64 ) μg/L和正常对照组(1.82±0 .83 ) μg/L ...
张忠英 +4 more
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Zhongguo shiyan zhenduanxue, 2010 目的探讨经尿道诊断性膀胱肿瘤电切在膀胱癌准确分期的临床应用价值。方法回顾性分析我院在1995年3月至2005年3月期间收治的行经尿道膀胱肿瘤电切术（经典术式）的199例膀胱癌患者,与在2006年5月-2009年1月期间收治的行经尿道诊断性膀胱肿瘤电切术的82例膀胱癌患者临床随访资料。结果①在行经尿道膀胱肿瘤电切术的膀胱癌患者中,术后两内年膀胱癌原位复发6例,术后5年、7年膀胱内无肿瘤复发,而出现盆腔淋巴结转移及全身骨转移2例。②在行经尿道诊断性膀胱肿瘤电切的膀胱癌患者中 ...
孙铙 +7 more
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Zhongguo shiyan zhenduanxue, 2004 目的 探讨尿脱落细胞DNA分析在膀胱癌诊断中的临床意义。方法 利用流式细胞仪对良性血尿、膀胱肿瘤及膀胱癌患者尿脱落细胞进行DNA倍体和SPF分析。结果 良性血尿患者为正常二倍体DNA分析图谱。膀胱肿瘤患者二倍体肿瘤 2 2例 ,异倍体肿瘤 4例 ;而膀胱癌患者二倍体肿瘤 8例 ,异倍体肿瘤 38例 ;膀胱癌、膀胱肿瘤患者的SPF（15 5 3± 6 5 4 ,9 37± 5 0 5 ）明显高于良性血尿患者 （5 6 7± 2 4 8,P
邱莲女, 周永列, 林慧君
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