Results 71 to 80 of about 1,989 (120)

巨噬细胞移动抑制因子在原发性肝癌中的临床意义 [PDF]

, 2007
【目的】探讨肝癌患者血清巨噬细胞移动抑制因子（macrophage migration inhibitory factor,MIF）水平与其临床特征及预后的关系。【方法】用酶联免疫吸附法检测2004年1月至2006年5月60例确诊初治的原发性肝癌患者的血清MIF水平,并与30例健康人相比较,分析其与临床特征及预后的关系。【结果】原发性肝癌患者血清MIF水平较健康对照组显著升高（中位值,34.1ng/mL与15.9ng/mL,P〈0.001）。血清MIF水平与血管侵犯（P=0.014 ...
吴祥元, 林曲, 汪清铭, 温景芸, 董敏, 黄明声   +5 more
core  

A small-molecule inhibitor B57 plays a role in the process of NLRP3 inflammasome activation [PDF]

, 2017
炎症小体是先天免疫系统中一类重要的胞内信号复合体。炎症小体的激活可以引发白介素1β（IL-1β）和白介素18（IL-18）的成熟和分泌，同时引发细胞焦亡。NLRP3炎症小体是迄今为止，研究最为广泛的炎症小体，它的上游刺激物性质各异，种类庞杂。研究表明，被激活的NLRP3向下游传递信号，依赖于模式识别受体对双接头蛋白ASC的招募，进而促使ASC在胞内形成大型蛋白复合体，激活炎症相关Caspase1。然而NLRP3招募相互作用蛋白ASC的过程，可能是其信号传递被调控的关键步骤 ...
郑振渊
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哮喘患儿的外周血淋巴细胞CD40/CD40L的表达及其与Tc1和Tc2的关系 [PDF]

, 2007
【目的】研究发作期哮喘患儿的外周血CD40、CD40L的表达率及其与Tc1和Tc2的关系。【方法】应用流式细胞术检测30例哮喘患儿和20例正常对照儿童的外周血淋巴细胞CD40、CD40L的表达率和Tc1、Tc2的细胞数。【结果】哮喘患儿和正常对照组的外周血淋巴细胞CD40表达率分别为21.59±7.61和15.82±4.44(t=3.376,P0.05);Tc2细胞数分别为7.64±3.67和3.02±1.38(t=3.981,P0.05)。【结论】发作期哮喘患儿存在明显的CD40/CD40L、Tc1 ...
刘甜甜, 吴葆菁, 檀卫平, 魏菁, 麦贤弟, 黄花荣   +5 more
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[cGAS-STING agonist cGAMP enhances natural killer cell-mediated cytotoxicity against gastric cancer cells]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Wang Q, Chai Z, Deng Y, Zhang Z, Gong Y, Gao S, Feng P.   +6 more
europepmc   +1 more source

[Aggressive natural killer cell leukemia with hemophagocytic lymphohistiocytosis: a case report]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Yang JH, Zhou QM, Xu XY, Yao XM, Luo YM, Chen QT, Guo ZZ, Li TH.   +7 more
europepmc   +1 more source

Co-culture of natural killer cells and tumor spheroids on a heterogeneous multilayer paper stack. [PDF]

J Zhejiang Univ Sci B
Xie Y, Yang X, Pan R, Gao L, Yu L.
europepmc   +1 more source

[Research progress on the role of invariant natural killer T cells in immune-mediated liver injury]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Bai LX, Hao WK, Li JR, Li SF, Zhang LT, Li JF.   +5 more
europepmc   +1 more source

[Current status of research on the impairment of natural killer cell function caused by hepatitis B virus infection]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Zhu XY, Zhou YF, Zhu SG.
europepmc   +1 more source

[Flow cytometry analysis of normal range of natural killer cells and their subsets in peripheral blood of healthy Chinese adults]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Tian J, Guo Y, Zhang X, Sun X, He J.
europepmc   +1 more source

[A mechanistic study of radiotherapy on intratumoral NK cell infiltration augmentation by regulating the EZH2/CXCL10 pathway in hepatocellular carcinoma cells]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Zhao XF, Wang Q, Sun J, Zhang AM, Chang XY, Li WG, Duan XZ.   +6 more
europepmc   +1 more source