哮喘患儿的外周血淋巴细胞CD40/CD40L的表达及其与Tc1和Tc2的关系 [PDF]
【目的】研究发作期哮喘患儿的外周血CD40、CD40L的表达率及其与Tc1和Tc2的关系。【方法】应用流式细胞术检测30例哮喘患儿和20例正常对照儿童的外周血淋巴细胞CD40、CD40L的表达率和Tc1、Tc2的细胞数。【结果】哮喘患儿和正常对照组的外周血淋巴细胞CD40表达率分别为21.59±7.61和15.82±4.44(t=3.376,P0.05);Tc2细胞数分别为7.64±3.67和3.02±1.38(t=3.981,P0.05)。【结论】发作期哮喘患儿存在明显的CD40/CD40L、Tc1 ...
刘甜甜 +5 more
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TFF2 Regulates LPS-induced Macrophages Polarization and Inhibits Inflammation [PDF]
病原感染修复过程中,不同极化分型的巨噬细胞与微环境相互作用,启动促炎或抗炎机制:一方面,巨噬细胞M1型活化,释放炎症介质,导致炎症发生,进而损伤;另一方面,巨噬细胞M2型活化启参与炎症控制和寄生虫感染抵抗,并在组织修复与重建、脂类代谢、过敏反应和肿瘤形成中发挥作用。两种机制相互拮抗共同决定着炎症的发生发展及转归。因此,巨噬细胞不仅是重要的疾病治疗靶点,其极化调控也成为研究热点之一。最新研究进展提示脂多糖(LPS)是炎症和巨噬细胞M1型极化的强大诱导剂。LPS主要通过TLRs受体激活NF- ...
吴晓玲
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[cGAS-STING agonist cGAMP enhances natural killer cell-mediated cytotoxicity against gastric cancer cells]. [PDF]
Wang Q +6 more
europepmc +1 more source
[<i>Streptococcus salivarius</i>-derived extracellular vesicles exacerbate progression of lupus nephritis by activating natural killer cells]. [PDF]
Xiao J, Jin L, Duan L, Gong Y, Li H.
europepmc +1 more source
[Aggressive natural killer cell leukemia with hemophagocytic lymphohistiocytosis: a case report]. [PDF]
Yang JH +7 more
europepmc +1 more source
Co-culture of natural killer cells and tumor spheroids on a heterogeneous multilayer paper stack. [PDF]
Xie Y, Yang X, Pan R, Gao L, Yu L.
europepmc +1 more source
[Research progress on the role of invariant natural killer T cells in immune-mediated liver injury]. [PDF]
Bai LX +5 more
europepmc +1 more source
[Current status of research on the impairment of natural killer cell function caused by hepatitis B virus infection]. [PDF]
Zhu XY, Zhou YF, Zhu SG.
europepmc +1 more source
[Flow cytometry analysis of normal range of natural killer cells and their subsets in peripheral blood of healthy Chinese adults]. [PDF]
Tian J, Guo Y, Zhang X, Sun X, He J.
europepmc +1 more source
[A mechanistic study of radiotherapy on intratumoral NK cell infiltration augmentation by regulating the EZH2/CXCL10 pathway in hepatocellular carcinoma cells]. [PDF]
Zhao XF +6 more
europepmc +1 more source

