在本研究中,制备了Aβ寡聚体和交联该寡聚体的亲和层析填料,然后应用亲和层析技术从IVIG中纯化获得了结合Aβ寡聚体的多克隆抗体(antibodies against Aβoligomer,Ab-Aβo),并应用ELISA和Western blot对其进行了鉴定,以MTT实验分析了该抗体对Aβ42诱导的细胞毒性作用的影响.结果表明,纯化获得的Ab-Aβo能特异性地结合体外合成或细胞形成的Aβ寡聚体,并且与A&beta ...
汪维云, 季梅, 王腾, 谢喜秀
core
目的探讨相关糖尿病自身抗体谱检测对儿童糖尿病的诊断及治疗方面的临床价值,包括血清谷氨酸脱羧酶抗体(glutamic acid decarboxylase antibody,GADA)、胰岛素自身抗体(anti-insulin autoantibody,IAA)、胰岛细胞抗体(islet cell autoantibody,ICA)、锌转运蛋白8抗体(zinc transporter 8 antibody,ZnT-8A)、酪氨酸磷酸酶抗体(ayrosine phosphatase antibody-2A ...
余悠悠 +3 more
doaj
[Whole blood exchange for a critically ill patient with Hodgkin lymphoma complicated by severe autoimmune hemolytic anemia: a case report and literature review]. [PDF]
Li BQ +10 more
europepmc +1 more source
[Systemic sclerosis with anti-human neutrophil cytoplasm antibody associated vasculitis: A case report]. [PDF]
Yang L, Zou J.
europepmc +1 more source
[A cross-subject stress recognition method integrating bidirectional cross-modal multi-path fusion and adaptive adversarial learning]. [PDF]
Wang P, Zhu M, Chou Y, Wei X, Liu S.
europepmc +1 more source
[Role of HLA genetic variants in autoimmune diseases]. [PDF]
Rao T, Chen L, Wei Q, Ouyang D.
europepmc +1 more source
[IgG4-related disease presenting with involvement of the eyes, pituitary gland and nervous system: A case report]. [PDF]
Hao C, Li Z, Qin L, Yin Y.
europepmc +1 more source
[One-stage debridement and internal fixation exchange combined with continuous local antibiotic irrigation in treatment of fracture-related infection]. [PDF]
Wu G +5 more
europepmc +1 more source
[Livedoid vasculopathy: A case report]. [PDF]
Li J +6 more
europepmc +1 more source

