Results 21 to 30 of about 4,738 (163)
NRP- 1 monoclonal antibody in combination with metronomic chemotherapy (MCT) inhibits the growth of gastric cancer xenografts in nude mice [PDF]
, 2017 目的:探讨NRP-1单抗联合多西他赛节律化疗对胃癌裸鼠移植瘤的抗肿瘤疗效。方法:BALB/c裸鼠皮下接种胃癌BGC-823细胞制备移植瘤模型,将; 荷瘤裸鼠以数字随机表法随机分为对照组、NRP-1单抗组、节律化疗组(MCT)、联合组(NRP-; 1mAb+MCT),每组6只。除对照组,其余各组于造模第8天开始分别给予相应治疗,给药2周,观察裸鼠一般状况,隔天测量裸鼠体重及肿瘤体积。裸鼠处; 死后称瘤质量,H-E染色观察瘤组织形态,免疫组化检测裸鼠瘤组织中NRP-1蛋白、VEGF、MVD表达。结果 ...
丁园, 徐芸, 陈玉强, 颜江华
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Role of Light Therapy in Circadian Rhythm Sleep-wake Disorders [PDF]
, 2022 Circadian rhythm sleep-wake disorder (CRSWD) affects people's health and well-being.Current treatments mainly include exogenous melatonin therapy and light therapy, among which light therapy plays an important role in the treatment of CRSWDas a non ...
CHEN Feng, FAN Mei, XIANG Ting, PAN Jiyang
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Integrative Conservation, Volume 5, Issue 1, Page 125-136, March 2026.We collated detections of the sun bear from new and previously published camera trap studies across its range. We then analysed these detections at two different spatial scales to assess the habitat associations and diel activity of this species. We found that the sun bear is tolerant to moderate habitat disturbances. ABSTRACT Degraded tropical forests,
Alexander Hendry +5 more
wiley +1 more source
The Effects of EA-ACR Promoting Plasma Melatonin of Insomnia Rats induced by PCPA [PDF]
, 2016 失眠是现如今临床常见的一种睡眠障碍性疾病，也越来越受到全球范围的重视。目前对失眠的研究大多集中于临床研究中，而针对失眠的基础机制研究很少，还有待进一步完善。 褪黑素是近几年来研究较多的与失眠密切相关的一种激素。为了进一步探讨失眠的病理机制，本实验共选用36只雄性SD大鼠，采用PCPA腹腔注射致失眠模型，用耳甲区电针刺激的方法，通过测定大鼠体重、旷场试验及血浆褪黑素分泌水平变化，从而探讨耳甲区电针调节失眠大鼠睡眠情况的机制。 结果：（1）PCPA腹腔注射28-30h后,大鼠睡眠出现昼夜节律性改变 ...
徐伟伟
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Journal of Critical Infrastructure Policy, Volume 7, Issue 1, Spring/Summer 2026.ABSTRACT Time and chronology form the invisible architecture upon which modern civilization depends, governing synchronization across markets, power grids, communication networks, transportation, and defense. Yet, this shared temporal framework, engineered through atomic clocks, satellites, and digital synchronization, faces growing vulnerabilities ...
Bilal M. Ayyub
wiley +1 more source
The effect of thyroid hormone on GLUT4 and its relationship with cardiolipin [PDF]
, 2016 课题组前期的研究结果表明，甲亢性心脏功能变化与心磷脂关系密切，本研究拟从GLUT4(Glucosetransporter4，葡萄糖转运蛋白4)变化的角度进一步探讨心磷脂在甲亢中的作用。 心脏作为一个高能量代谢的组织，主要通过线粒体中氧化磷酸化产生ATP来提供能量，并且对葡萄糖体现出高度依赖性。而GLUT4是糖转运体蛋白家族中的一员，在葡萄糖的非ATP-依赖膜转运过程中起着重要作用。因此，对于以高代谢为主要变化的甲亢，探讨GLUT4是有必要的。而且，文献报道甲状腺激素可促进心肌组织中GLUT4的表达 ...
孙婷
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International Journal of Urban and Regional Research, Volume 50, Issue 1, Page 191-220, January 2026.Abstract Henry George advocated for capturing land value increases for public ends. The active approach of public authorities organizing and financing land development can help capture higher land value increases, as Hartman and Spit indicate. However, this approach hardly happens in developing countries, where the coalition of private developers and ...
Nannan Xu
wiley +1 more source
Evaluating left atrial function and predicting the efficacy of radiofrequency catheter ablation with persistent atrial fibrillation by speckle tracking imaging [PDF]
, 2015 目的：探讨应用斑点追踪技术（STI）评价持续性房颤患者经导管射频消融（RFCA）术前、术后左心房结构功能变化，并预测房颤患者经导管射频消融术后随访至术后6个月维持窦性心律的可能性。方法：对45例经皮导管射频消融术的持续性房颤患者分别于术前1周、术后24小时、术后3个月、术后6个月和25例对照组（健康志愿者）进行左房结构功能及应变率分析，测量和计算左房前后径指数（LADI）、左房面积指数（LAAI）、左房最大容积指数（LAVImax）、左房射血分数（LAEF）、E/E ...
钟小芳
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Using online reports of seahorse seizures to track their illegal trade
Conservation Biology, Volume 39, Issue 5, October 2025.Abstract Illegal wildlife trade (IWT) is a persistent and extensive threat to global biodiversity. Hundreds of marine fish species are subject to regulation under the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES), but it is unclear how much protection species gain from CITES because information on marine fish ...
Sarah J. Foster +3 more
wiley +1 more source
当代中国政法生态下的维权律师 = A study on the rights defence lawyers under the current political & legal ecology in China [PDF]
, 2015 University of Technology Sydney. Faculty of Arts and Social Sciences.近十多年来，中国律师职业中形成了一个带有“维权”标签的松散律师群体：维权律师。维权律师群体的形成，在中国当代社会、法律和政治现实运作中引起了相当的争鸣和反思，甚至制度性冲突和对抗。党国体制和依法治国的宏观理论指导与微观社会实践都已经面临从“不争论”到“讲清楚”的临界点。 本论文试图从实证研究的角度出发，以法律社会学为主要理论框架，尽可能通过个案案例分析来了解 ...
Gu, Ming
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