Results 1 to 10 of about 1,378,710 (155)

Modified rush venom immunotherapy in dogs with Hymenoptera hypersensitivity

Veterinary Dermatology, Volume 34, Issue 6, Page 532-542, December 2023., 2023
Background – Hymenoptera envenomation occurs frequently in people and dogs and can trigger anaphylaxis. Venom immunotherapy (VIT) is the only preventative treatment for Hymenoptera hypersensitivity and is indicated for people with severe adverse reactions to insect stings. Rush VIT is an accelerated VIT induction schedule performed in people.
Alexandra Moore, Amanda K. Burrows, Wayne S. Rosenkrantz, Rudayna M. Ghubash, Giselle Hosgood   +4 more
wiley   +1 more source

DUAL I China: Improved glycemic control with IDegLira versus its individual components in a randomized trial with Chinese participants with type 2 diabetes uncontrolled on oral antidiabetic drugs DUAL I China:在一项对未服用口服降糖药物的中国2型糖尿病患者进行的随机试验中, IDegLira与其单独成分相比改善了血糖控制

Journal of Diabetes, Volume 14, Issue 6, Page 401-413, June 2022., 2022
Highlights Insulin degludec/liraglutide (IDegLira) has good efficacy and tolerability in Chinese adults with type 2 diabetes not controlled on oral antidiabetic drugs. IDegLira provides the clinical advantages of insulin and glucagon‐like peptide 1 receptor agonists, improving glycemic control while reducing the main adverse effects of insulin (weight ...
Weiqing Wang, Bue F. Ross Agner, Bin Luo, Lei Liu, Ming Liu, Yongde Peng, Shen Qu, Karolina Amelia Stachlewska, Guixia Wang, Guoyue Yuan, Qiu Zhang, Guang Ning   +11 more
wiley   +1 more source

A novel therapeutic diet can significantly reduce the medication score and pruritus of dogs with atopic dermatitis during a nine‐month controlled study

Veterinary Dermatology, Volume 33, Issue 1, Page 55-e18, February 2022., 2022
Background – Canine atopic dermatitis (cAD) is a common chronic relapsing pruritic skin disease for which management commonly relies on life‐long use of immunomodulatory drugs. A number of the medications used are associated with adverse effects and the potential for complications during long‐term use.
Adrian Watson, Ana Rostaher, Nina M Fischer, Claude Favrot   +3 more
wiley   +1 more source

Chemical and microbiological stability of diluted ceftazidime in three different solutions under three storage temperatures over a 28 day period

Veterinary Dermatology, Volume 32, Issue 5, Page 456-e124, October 2021., 2021
Background – Ceftazidime (CAZ) solutions are being used based on anecdotal reports for otitis externa complicated by multidrug‐resistant Pseudomonas aeruginosa (MDR PA). The chemical and microbiological stability of these proposed compounded solutions have not been evaluated, and likely are affected by the diluent and storage duration or temperature ...
Sarah E. Hoff, Darren J. Berger, Austin K. Viall, Dwayne Schrunk, James O. Noxon   +4 more
wiley   +1 more source

Effectiveness of a hydrophobic dressing for microorganisms’ colonization of vascular ulcers: Protocol for a randomized controlled trial (CUCO‐UV Study) 疏水性敷料对血管溃疡中微生物定植的有效性:随机对照试验方案(CUCO‐UV研究)

Journal of Advanced Nursing, Volume 76, Issue 8, Page 2191-2197, August 2020., 2020
Abstract Aim To determine the effectiveness of a hydrophobic dressing (Cutimed Sorbact®) against a silver dressing (Aquacel® Ag Extra) in the level of colonization of chronic venous leg ulcers. The secondary endpoints are health‐related quality of life, level of pain, and time to complete healing.
Juan C. Morilla‐Herrera, José M. Morales‐Asencio, Alberto J. Gómez‐González, Antonio Díez‐De Los Ríos, Inmaculada Lupiáñez‐Pérez, Carlos Acosta‐Andrade, Marta Aranda‐Gallardo, Ana B. Moya‐Suárez, Shakira Kaknani‐Uttumchandani, Silvia García‐Mayor   +9 more
wiley   +1 more source

Efficacy study of a topical treatment with a plant extract with antibiofilm activities using an in vivo model of canine superficial pyoderma

Veterinary Dermatology, Volume 31, Issue 2, Page 86-e8, April 2020., 2020
Background Canine pyoderma is a common skin infection caused predominantly by staphylococcal bacteria. Because of increasing rates of antimicrobial resistance in bacterial isolates, there is an urgent need for alternative or supplementary treatment options.
Wolfgang Bäumer, Megan Jacobs, Chie Tamamoto‐Mochizuki   +2 more
wiley   +1 more source

医院碳青霉烯耐药肺炎克雷伯菌的耐药特征分析

Zhongguo shiyan zhenduanxue, 2022
目的 分析碳青霉烯耐药肺炎克雷伯菌的耐药表型和基因型等特征，为临床抗感染治疗提供实验依据。方法 收集2017年5月至2021年4月间住院患者感染性标本中分离的碳青霉烯耐药肺炎克雷伯菌，采用VITEK-2compact全自动细菌鉴定/药敏分析系统对碳青霉烯耐药菌株进行鉴定和药敏试验，应用SPSS Statistics 17.0软件进行耐药率差异分析。结果 共获得碳青霉烯耐药肺炎克雷伯菌55株，耐药菌株来源于痰液标本31株、尿液标本14株、血液标本10株；药敏结果显示 ...
孙胜君, 张昌莲, 赵自云
doaj  

血浆外泌体miR-21对胃癌细胞药物敏感性的影响

Zhongguo shiyan zhenduanxue, 2022
目的 探索外泌体来源的miR-21作为胃癌奥沙利铂化疗过程中评价药物敏感性生物标志物的价值。方法透射电镜观察外泌体的形态；构建SGC7901奥沙利铂耐药细胞株，并利用RT-qPCR检测耐药细胞和亲本细胞中miR-21的表达水平；CCK8检测miR-21对SGC7901耐药细胞株增殖抑制率的影响；Western blot检测外泌体的标记蛋白；使用受试者工作特征曲线（ROC）分析奥沙利铂治疗胃癌的过程中miR-21评估药物敏感性的价值。结果miR-21过表达后，亲本细胞对奥沙利铂的敏感性由IC50 16 ...
杜沛, 李婷, 文雯
doaj  

人胃癌耐药细胞的建立方法及意义

Zhongguo shiyan zhenduanxue, 2021
目的 建立人胃癌耐药细胞,为研究人胃癌耐药细胞的耐药机制以及为耐药肿瘤细胞的治疗提供耐药肿瘤细胞模型。方法 体外培养人胃癌细胞SGC-7901,用50μmol/L顺铂多次反复冲击,对冲击4次和6次的SGC-7901分别检测对顺铂的抑制率和多药耐药基因（MDR）及多药耐药特异基因片段的表达,并计算药物对细胞的半数抑制浓度（IC50）。结果 经4次和6次冲击后,受冲击的SGC-7901胃癌细胞对顺铂的抑制率明显高于亲本细胞,IC50为63.98μmol/L和66.34μmol/L,而亲本细胞SGC ...
刘玉侠, 齐红, 段北野, 付尧, 夏莉, 于鸿, 王斌   +6 more
doaj  

International clinical practice recommendations on the definition, diagnosis, assessment, intervention, and psychosocial aspects of developmental coordination disorder – Chinese (Mandarin) translation

Developmental Medicine &Child Neurology, Volume 61, Issue 3, Page E1-E35, March 2019., 2019
目的 本国际临床指南由欧洲残疾儿童学会（the European Academy of Childhood Disability，EACD）牵头制定，旨在解决发育性协调障碍（developmental coordination disorder，DCD）的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题，通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础，以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类，最终转化为指南建议。并由国际 ...
Jing Hua, Wenchong Du, Xiaotian Dai, Meiqin Wu, Xianying Cai, Min Shen, Liping Zhu   +6 more
wiley   +1 more source