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某院鲍曼不动杆菌血流感染治疗方案的制定 [PDF]

open access: yes, 2018
目的:制定某院鲍曼不动杆菌血流感染的治疗方案。方法:收集某院2015-2016年血标本培养出的鲍曼不动杆菌39株,测定对氨苄西林舒巴坦,替加环素,亚胺培南,美罗培南的最低抑菌浓度。运用蒙特卡洛方法计算不同方案的达标概率(PTA)和累积反应分数(CFR)。结果:氨苄西林舒巴坦3 g q6h对鲍曼不动杆菌的CFR为66.05%,替加环素50 mg q12h,100mg q12h的CFR分别为95.75%和99.77%,亚胺培南1 g q8h,q6h和美罗培南1 g q8h,q6h的CFR分别是67.74 ...
孙洲亮   +3 more
core   +1 more source

应用质谱法和显色培养法对真菌血流感染鉴定的比对研究

open access: yesZhongguo shiyan zhenduanxue, 2023
近年来,随着激素、广谱抗生素、免疫抑制剂的广泛应用,真菌引起的血流感染日渐增多。念珠菌是真菌血流感染最常见的病原菌,并且真菌感染比细菌感染死亡率更高,治疗效果也相对更差[1]。为了降低血流感染的发病率和死亡率,早期有针对性的抗菌药物治疗是关键,故临床对真菌的快速准确鉴定成为目前迫切解决的问题。
宋伶俐, 李密阳, 马琳琳
doaj  

Prevalence of Eight Viruses in Captive Amur Tigers (Panthera tigris altaica) From Harbin, China 中国哈尔滨市圈养东北虎8种病毒的流行

open access: yesWildlife Letters, EarlyView.
The Amur tiger, an endangered flagship species mainly found in the Russia Far East and Northeastern China, holds immense biological importance, and has been listed under the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES).
Wei Xie   +15 more
wiley   +1 more source

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

open access: yesVeterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis   +9 more
wiley   +1 more source

Impact of inadequate initial antimicrobial therapy on mortality in patients with bacteraemic cholangitis: a retrospective cohort study [PDF]

open access: yes, 2020
順天堂大学博士(医学)2019年度doctoral ...
タガシラ, ヤスアキ   +1 more
core   +1 more source

A blinded randomised split‐body clinical trial evaluating the effect of fluorescent light energy on antimicrobial management of canine interdigital furunculosis

open access: yesVeterinary Dermatology, Volume 36, Issue 3, Page 291-301, June 2025.
Background – Canine interdigital furunculosis (CIF) is a complex, relapsing inflammatory condition, typically complicated by deep bacterial infections requiring prolonged systemic antibiotics. Hypothesis/Objectives – This split‐body study, where dogs acted as their own control, evaluated whether the adjunctive use of fluorescent light energy (FLE ...
A. Lange   +12 more
wiley   +1 more source

Ongoing outbreak of maternal parvovirus B19 infections in Germany since end of 2023: consequence of COVID‐19 pandemic?

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 4, Page 456-461, April 2025.
Abstract Objective To investigate the ongoing parvovirus B19 (B19V) outbreak among pregnant women in Germany and its connection to the coronavirus disease 2019 (COVID‐19) pandemic. Methods This retrospective cohort study analyzed anonymous data regarding serologically confirmed B19V infections during pregnancy between January 2014 and April 2024 across
J. Jiménez Cruz   +14 more
wiley   +1 more source

血液科住院患者血流感染病原菌特征及预后的临床研究

open access: yesZhongguo shiyan zhenduanxue, 2021
血液病住院患者由于疾病自身原因,需长期住院治疗,大量使用抗生素和化疗药物,患者常有中性粒细胞减少,免疫功能缺陷,极易感染各种病原菌。另外,中心静脉导管的广泛使用和造血干细胞移植,进一步增加了患者感染的风险。血液病血流感染患者的粗死亡率从12%-42%不等,一些研究报道的可归因死亡率高达38%[1-3]。血培养是诊断血流感染的重要手段,可为临床合理应用抗菌药提供依据,减少耐药性的产生,改善患者预后[4-5]。由于化疗、
车辉娟, 孙霞, 胡宏章, 康梅
doaj  

Optimization of beta lactam antibiotics regimens against bloodstream infection caused by Pseudomonas aeruginosa [PDF]

open access: yes, 2017
目的制定某院beta内酰胺类在铜绿假单胞菌(PA)血流感染中的治疗方案。方法收集某院2015年至2016年血培养中铜绿假单胞菌共64株,测定; beta内酰胺类(哌拉西林/他唑巴坦,头孢他啶,头孢吡肟,亚胺培南,美罗培南)对铜绿假单胞菌的最低抑菌浓度(MIC)。用蒙特卡洛模拟计算多种治疗; 方案的达标率(PTA)和累积反应分数(CFR)。结果经验治疗时,哌拉西林/他唑巴坦4.5 g(q6 h),头孢他啶2 g(q8 h),头孢吡肟2; g(q8 h),亚胺培南1 g(q6 h),美罗培南1 g(q8 h,
于迪   +4 more
core  

Exploring barriers to menstrual education between maternal figures and young girls: A pilot study in South Africa

open access: yesSexuality, Gender &Policy, Volume 7, Issue 3, Page 305-321, August 2024.
Abstract The study sought to explore barriers to menstrual education between maternal figures and young girls. Menstruation is a key part of the reproductive process and affects young adolescent girls. Menstrual blood is perceived as contaminating and impure, leading to the socialization of women and girls undergoing menstruation to feel soiled and ...
Viwe Sobudula, Dhee Naidoo
wiley   +1 more source

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