Results 51 to 60 of about 12,455 (196)
Toxicity Study of VOSO_4 Using NMR-based Metabonomics [PDF]
, 2010 通讯作者：陈忠 E-mail: chenz@xmu.edu.cn[中文文摘]采用基于核磁共振(NMR)的代谢组学方法,结合生化指标分析及组织病理学检测,研究了具有类胰岛素活性的硫酸氧钒(VOSO4)对Wistar大鼠的毒性作用.通过不同剂量的VOSO4对Wistar大鼠连续灌胃给药16d,收集大鼠的血清和尿液,并采集样品的1H NMR谱进行多变量数据统计分析来辨识其特征代谢物,然后采用TICL(a web Tool for automatic Interpretation of Compound ...
危阳洋 +4 more
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Toxicity Study of VOSO4 Using NMR-based Metabonomics [PDF]
, 2010 NMR-Based metabonomics combined with clinical biochemical analysis and histopathological examination was applied to investigate the toxicity effects of vanadyl sulfate with insulin-like activity in male Wistar rats.
Chen Zhong +9 more
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Effects of Saponins of Semen Ziziphi Spinosae on Oxidative Damage of Liver and Kidney and Intestinal Microflora in Lead-exposed Mice [PDF]
Objective: To investigate the effects of saponins of Semen Ziziphi Spinosae (SSZS) on liver and kidney oxidative damage and intestinal flora composition in lead-exposed mice and explore its detoxification mechanism. Methods: The Pb-intoxicated mice model
Lihong LIU, Weidong CAO
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野生动物学报, 2016 我们对1只处于昏迷状态的野生雕鸮进行了救护。经过临床检查和实验室检查发现,动物体况良好,体温、心率以及肌酐、尿素氮、转氨酶、碱性磷酸酶、总蛋白、白蛋白等8项血液生化指标均无异常,排除了外伤、有机磷和氨基甲酸酯类农药和有机氟类、磷化锌类、毒鼠强等剧毒鼠药中毒的可能性,初步判断为抗凝血类或硫脲类鼠药二次中毒。按照不明毒物中毒发生时的一般治疗方法进行治疗,护理中最大限度减少对动物的刺激。治疗2 d后开始采食活的实验小鼠,9 d后完全康复,并成功放归野外。放归前,分析了14项血液生化指标 ...
许 杰 张延君 肖景贵 侯志军
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Pathological characteristics of enterotoxigenic Escherichia coli K88 and screening of its probiotics [PDF]
, 2008 在获得绿色荧光蛋白(GFP)标记的菌株K88-GFP并证明其与K88具有遗传同质性的基础上,以K88-GFP为致病菌,腹腔注射侵染小鼠,在不同时间进行眼球采血,测定血液生理生化指标,并采取不同器官或组织,培养后利用紫外光激发K88-GFP的绿色荧光,观察计数这种产肠毒素性大肠杆菌(ETEC)在小鼠体内的分布。同时通过体外抑制和活体饲喂试验,进行了益生菌的筛选。结果证实,ETEC致病菌具有较强的侵袭性,它可以侵袭小鼠肝、肾、心、肺及脑、肌肉等器官和组织,尤其可对肝、肾造成严重的损伤;筛选得到益生菌株PB ...
刘波 +4 more
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Improvement of Exercise Ability and Liver Protection in Oxidative Stress-induced Mice by Lactiplantibacillus plantarum CQPC03 [PDF]
This study investigated the effects of a newly discovered lactic acid bacterium, Lactiplantibacillus plantarum CQPC03 (LP-CQPC03), on enhancing the exercise capacity of mice under oxidative stress and elucidated the underlying mechanisms.
Bo HE +4 more
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野生动物学报, 2018 本研究旨在研究水苏糖对圈养猕猴肠道菌群(双歧杆菌、乳酸杆菌及大肠杆菌)含量及血液生理生化指标的影响,为水苏糖在动物上的应用提供参考依据。研究将福州动物园兽类表演场圈养猕猴分为对照组和试验组(包括幼年组、成年组和老年组),给其饲喂6 周的水苏糖(双歧杆菌促生长因子,非消化性低聚糖),利用荧光定量PCR(qPCR)的方法检测猕猴粪便双歧杆菌、乳酸杆菌及大肠杆菌的数量; 用全自动血液细胞分析仪和全自动血液生化分析仪,检测饲喂水苏糖前后猕猴血液生理生化指标的变化。结果:不同年龄段的试验组粪便双歧杆菌量均有增加 ...
杨世丽 李海芳 陈科元 陈小丽 唐 耀 马燕梅
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Immunomodulatory Function and Safety Evaluation of Compound Preparation Containing Ganoderma lucidum Polysaccharides [PDF]
Objective: To evaluate the immunomodulatory function and safety of compound preparation containing Ganoderma lucidum polysaccharides. Methods: According to the Technical Standards for Testing and Assessment of Health Food (2003 Edition), the ...
Deshan NING +6 more
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Zhongguo shiyan zhenduanxue, 2007 目的研究海洛因依赖及腺苷补偿时大鼠肾功能生化指标的变化和意义。方法建立海洛因依赖及腺苷补偿组大鼠模型,50只Wistar大鼠随机分成对照组、3 d给药组9、d给药组、腺苷对照组及同时给海洛因和腺苷9天组,检测血液生化指标尿素氮（BUN）、肌酐（CREA）及尿酸URIC)。结果与对照组相比,海洛因3天、9天给药组中URIC含量均明显升高 ...
崔佳乐 +5 more
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