Results 21 to 30 of about 14,334 (168)
Highlights This is a systematic review‐based clinical practice guideline. After internal and external review, two strong recommendations, six conditional recommendations, and one qualifying statement were made for insulin‐naive adult patients with type 2 diabetes.
Linong Ji +19 more
wiley +1 more source
Abstract Background Allergic skin diseases are common in horses worldwide. The most common causes are insect bites and environmental allergens. Objectives To review the current literature and provide consensus on pathogenesis, diagnosis, treatment and prevention. Materials and Methods The authors reviewed the literature up to November 2022.
R. Marsella +6 more
wiley +1 more source
UVA Assisted 4-Thiothymidine for Cancer Treatment [PDF]
This article reviews the developments of 4-thiothymidine analogues, assisted with UVA light, as a novel cancer therapy. First, the key points on synthetic chemistry, photochemistry and cellular toxicity of 4-thiothymidine are summarized.
Feng, Luo +3 more
core +1 more source
Highlights This study is the first registered meta‐analysis with three different insights to explore the relationship between the glycated hemoglobin (HbA1c) variability and the risk of cardiovascular disease (CVD). Our study suggests that the higher glucose fluctuation is significantly associated with the higher CVD risk in diabetes patients based on ...
Feng Li +6 more
wiley +1 more source
Highlights This is the first cross‐sectional study of the association between serum IGF2BP3 levels and odds of T2DM in high‐risk Chinese population. Two upregulated (IGF2BP2 and IGF2BP3) and 5 downregulated (METTL3, ALKBH1, YTHDF2, YTHDF3, and HNRNPC) m6A‐related genes could contribute to the occurrence of T2DM.
Xiaoying Wu +11 more
wiley +1 more source
Highlights The first multicenter, large‐sample study of the relationship between remnant cholesterol (RC) and diabetes. RC is independently associated with diabetes. RC represents residual diabetes risk beyond traditional lipids. Abstract Background The association between remnant cholesterol (RC) and diabetes remains unclear because of limited study ...
Binqi Li +11 more
wiley +1 more source
Study on the interactions of typical PAHs and their metabolites with serum albumin and their controlling ways using cyclodextrins [PDF]
血清白蛋白是血浆中含量最丰富的运输蛋白,对血液中许多内、外源物质具有广普的结合能力,具有重要的生理功能。多环芳烃(PolycyclicAromaticHydrocarbons,PAHs)及其代谢物可与血清白蛋白形成稳定的加合物,由此随血液循环转运分布至各组织器官,引起毒性效应。该结合过程也可对血清白蛋白的结构和功能产生不利影响。因此,深入研究PAHs及其代谢物与血清白蛋白的结合作用,探究PAHs对血清白蛋白结构和功能的影响及寻求该结合作用的调控方式对了解PAHs在生物体内的赋存状态、毒性强度及致毒机制 ...
张静
core
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis +9 more
wiley +1 more source
ABSTRACT Objectives To assess the value of pregnancy‐associated plasma protein‐A (PAPP‐A) in screening for preterm pre‐eclampsia (PE) (delivery < 37 weeks' gestation) measured in maternal blood samples collected before 11 weeks, and to compare the screening performance of PAPP‐A with that of placental growth factor (PlGF) from blood samples collected ...
L. Rode +21 more
wiley +1 more source
ABSTRACT Objective To compare the diagnostic performance of different manufacturers' immunoassays for the soluble fms‐like tyrosine kinase‐1 (sFlt‐1)‐to‐placental growth factor (PlGF) ratio with that of a point‐of‐care (PoC) test for glycosylated fibronectin (GlyFn) in women with suspected pre‐eclampsia (PE).
I. Y. M. Wah +7 more
wiley +1 more source

