Results 1 to 10 of about 1,519 (134)
Glutathione S transferase polymorphisms influence on iron overload in β-thalassemia patients [PDF]
Thalassemia Reports, 2013 In patients with β-thalassemia iron overload that leads to damage to vital organs is observed. Glutathione S transferase (GST) enzymes have an antioxidant role in detoxification processes of toxic substances. This role is determined genetically.
Serena Sclafani +5 more
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390名幼儿血清铁蛋白的测定及其对缺铁性贫血诊断的观察报告 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 1986 本文报道用125I放射免疫检测广州市两所全日制托幼儿园390名7岁以内小儿的血清铁蛋白（SF）。均值为30.00±12.80ng/ml（按每岁为一年龄组）,随年龄的增长,SF值越升高,SF在16ng/ml左右的,为储备铁缺乏（隐性缺铁阶段）但无明显临床症状。提示SF含量的变化对诊断隐性缺铁极为敏感。经铁强化糖浆饮料治疗后,其SF较治疗前明显升高（统计学处理极显著差异）,故讲明SF的测定不仅作为缺铁和缺铁性贫血诊断指标,而且还可作为铁剂治疗的疗效指标。
邓蔼莲
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Effects of Procyanidine on Rats Treated by Iron Overload under Condition of Simulated Weightlessness(原花青素对模拟失重条件下大鼠体内铁过载的影响) [PDF]
Shipin kexue jishu xuebao, 2015 The study aimed to investigate effects of procyanidine on rats treated by iron overload under the condition of simulated weightlessness. Simulated weightlessness was simulated by hind limb unloading rats, which maintained about -30° head down tilt ...
WANG Aidong(王爱东) +4 more
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The Clinical Value of PET-CT in the Diagnosis of Pre-pulseless Takayasu's Arteritis Presenting as Fever of Unknown Origine [PDF]
, 2022 BackgroundTakayasu's arteritis (TAK) presenting as fever of unknown origin (FUO) is rare in clinic. Diagnosis is difficult in the early stageas the non-specific clinical symptoms and signs, the lack of imaging findings of great artery stenosis and ...
ZENG Keqin, YIN Yufeng, REN Tian, ZHOU Erye, WANG Mingjun, WU Jian
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MRI-T2*检测β-重型地中海贫血心、肝、胰铁沉积的临床价值 [PDF]
, 2020 目的MRI-T2*定量评价β-重型地中海贫血（β-TM）患者心肌、肝脏、胰腺铁沉积程度，探讨心肌铁沉积与肝脏、胰腺铁沉积的关系。方法回顾性分析2014年5月至2016年1月期间在我院行心脏、肝脏、胰腺MRI-T2*检查的109例β-TM患者的临床、实验室和MRI资料，采用Spearman相关性分析探讨心肌T2*值与肝脏、胰腺T2*值之间关系。将心肌、肝脏铁沉积的患者纳入A组（n=32），仅肝脏铁沉积、而心肌铁含量正常的患者纳入B组（n=69），将心肌、胰腺铁沉积的患者纳入C组（n=34），仅胰腺铁沉积 ...
杨绮华 +4 more
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Research progress in ferroptosis regulation in the treatment of liver diseases [PDF]
, 2023 Ferroptosis is a form of cell death that results from accumulation of lipid reactive oxygen species, marked by iron-dependent oxidative damage of phospholipids. Accumulation of iron and lipid hydroperoxides are hallmarks of ferroptosis.
CHEN Chen +3 more
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Zhongguo shiyan zhenduanxue, 2022 目的 探讨常见的铁代谢指标在缺铁性贫血诊断中的应用价值。方法 选取缺铁性贫血（iron deficiency anemia,IDA）、慢性病贫血（anemia of chronic disease,ACD）和慢性病合并缺铁性贫血（chronic diseases with iron deficiency anemia,CIDA）以及健康对照（heathly,HS）4组标本，同时检测4组标本的常用铁代谢指标：可溶性转铁蛋白受体（soluble transferrin receptor,sTfR ...
侯立安 +5 more
doaj
, 2020 【目的】分析中山大学孙逸仙纪念医院的重型β-地中海贫血（β-TM）患者青春发育特点及影响因素。【方法】通过对42 例年龄≥10 岁β-TM 患者进行随访资料回顾、问卷调查、体格检查及实验室检查等评估青春发育状态，分析影响β-TM 患者青春发育的可能因素。【结果】24 例（57.14%）β-TM 患者出现青春发育异常，女性以乳房不发育、原发性闭经及男性以睾丸不增大、阴茎短小为主要表现。其中β0β0 基因型、脾切除后、维生素D 缺乏或者伴有糖尿病的β-TM 患者的青春发育异常发生率均显著增高 ...
侯乐乐 +5 more
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维持性血液透析患者血清低氧诱导通路相关指标水平与肾性贫血的相关性
Zhongguo shiyan zhenduanxue, 2020 目的研究维持性血液透析(MHD)患者血清低氧诱导通路相关指标表达水平与肾性贫血相关因素分析。方法选取2019年1月-2020年1月于吉林大学第二医院血液净化中心行规律血液透析治疗的MHD患者,根据血红蛋白(Hb)水平及是否应用促红细胞生成素(EPO)分为4组:EPO应答组、EPO低应答组、无贫血组、贫血未治疗组。采用双抗体夹心酶联免疫吸附法测定MHD患者的血清铁调素(Hepcidin)、低氧诱导因子1α(HIF-1α)、低氧诱导因子2α(HIF-2α)、脯氨酰羟化酶(PHD)的表达水平 ...
王金鑫 +5 more
doaj
Research progress in the relationship between iron deficiency and tic disorder [PDF]
Tic disorder is a common neurodevelopmental disorder disease in children， with a high prevalence and different clinical manifestations among individuals.
Wang Yun, Xiang Jingjing, Zheng Qian, Bai Jinxiu
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