Results 31 to 40 of about 135,387 (227)

Immunotherapy using pullulan‐conjugated Der f 2 allergen in canine atopic dermatitis: An anti‐inflammatory agent‐sparing approach

open access: yesVeterinary Dermatology, Volume 36, Issue 4, Page 443-452, August 2025.
Background – Allergen immunotherapy is used as aetiological treatment for canine atopic dermatitis (cAD). Objective – To assess the anti‐inflammatory agent‐sparing effect over 1 year of immunotherapy using pullulan‐conjugated recombinant Der f 2 (rDf2‐P). Conclusions and Clinical Relevance – Der f 2‐P immunotherapy can lead to a rapid reduction in anti‐
Masahiko Nagata   +7 more
wiley   +1 more source

改良简化的酸化血清溶血试验及其应用

open access: yesZhongguo shiyan zhenduanxue, 2004
目的 考察简化酸化血清溶血试验 (Ham试验 )用于筛查阵发性睡眠性血红蛋白尿症 (PNH)的效果。方法 对 2 0例正常人、16例PNH患者及 4 2例其它贫血患者进行用自身血清或AB血清或同型血清或混合血清的Ham试验 ,及蔗糖溶血 (糖水试验 )尿含铁血黄素检查 (Rous试验 )。结果 对已知PNH患者进行自身血清、AB血清、同型血清、混合血清的Ham试验检验 ,前三种血清阳性率均为 94 % ;而混合血清为 4 4 %。糖水试验、Rous试验阳性率分别为94 %、81%。结论 ...
李淑兰   +4 more
doaj  

慢性肺阻塞性疾病患者血清磷、血管内皮生长因子及成纤维细胞生长因子23水平分析

open access: yesZhongguo shiyan zhenduanxue, 2022
目的 探讨慢性肺阻塞性疾病患者血清磷、血管内皮生长因子及成纤维细胞生长因子23水平的相关性。方法 回顾分析武汉市红十字会医院收治的88例COPD患者为研究对象,其中稳定期58例,急性期30例。选择同期60例健康体检者为对照组,采用全自动生化分析仪检测血清磷水平,采用Elisa法检测患者的VEGF水平和FGF-23水平,并行相关性分析。结果 与对照组比较,稳定期组和急性期组患者的血清VEGF以及FGF-23水平明显高于对照组 ...
王茜, 彭金燕
doaj  

Applying Bergmann's Rule to Species Conservation Planning 贝格曼法则在物种保护规划中的应用

open access: yesIntegrative Conservation, Volume 4, Issue 2, Page 120-125, June 2025.
Although Bergman's rule has extensively been studied, its implications in species conservation have not been clear, especially in the context of climate change (global warming). Here, we discuss the potential applications of the “rule” based on IUCN's (2022) Red List and suggest species' body size to be an important ecological indicator in future long ...
Qinfeng Guo   +4 more
wiley   +1 more source

Study on the interactions of typical PAHs and their metabolites with serum albumin and their controlling ways using cyclodextrins [PDF]

open access: yes, 2016
血清白蛋白是血浆中含量最丰富的运输蛋白,对血液中许多内、外源物质具有广普的结合能力,具有重要的生理功能。多环芳烃(PolycyclicAromaticHydrocarbons,PAHs)及其代谢物可与血清白蛋白形成稳定的加合物,由此随血液循环转运分布至各组织器官,引起毒性效应。该结合过程也可对血清白蛋白的结构和功能产生不利影响。因此,深入研究PAHs及其代谢物与血清白蛋白的结合作用,探究PAHs对血清白蛋白结构和功能的影响及寻求该结合作用的调控方式对了解PAHs在生物体内的赋存状态、毒性强度及致毒机制 ...
张静
core  

Screening for pre‐eclampsia using pregnancy‐associated plasma protein‐A or placental growth factor measurements in blood samples collected at 8–14 weeks' gestation

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 5, Page 567-574, May 2025.
ABSTRACT Objectives To assess the value of pregnancy‐associated plasma protein‐A (PAPP‐A) in screening for preterm pre‐eclampsia (PE) (delivery < 37 weeks' gestation) measured in maternal blood samples collected before 11 weeks, and to compare the screening performance of PAPP‐A with that of placental growth factor (PlGF) from blood samples collected ...
L. Rode   +21 more
wiley   +1 more source

The role and mechanism of IL-33 in gout [PDF]

open access: yes, 2016
摘要 研究目的:以MSU诱导的小鼠实验性急性痛风为痛风研究模型,来探讨IL-33在急性痛风中的作用及其机制。 研究方法和结果: 1.重组小鼠IL-33的原核表达以及纯化 GST-IL-33融合蛋白经过原核表达、纯化,去除GST标签等步骤,获得了较高纯度的的mrIL-33。 2.对急性痛风患者血清中IL-33的研究 通过收集临床急性痛风患者41例(男39例,女2例)年龄26~91岁,平均58.3岁和44例年龄、性别与之匹配的健康志愿者的血清标本,检测血清中IL-33的含量。结果显示急性痛风患者血清中IL ...
苏群
core  

Ongoing outbreak of maternal parvovirus B19 infections in Germany since end of 2023: consequence of COVID‐19 pandemic?

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 4, Page 456-461, April 2025.
Abstract Objective To investigate the ongoing parvovirus B19 (B19V) outbreak among pregnant women in Germany and its connection to the coronavirus disease 2019 (COVID‐19) pandemic. Methods This retrospective cohort study analyzed anonymous data regarding serologically confirmed B19V infections during pregnancy between January 2014 and April 2024 across
J. Jiménez Cruz   +14 more
wiley   +1 more source

血清胱抑素C检测对早期高血压肾病的临床价值

open access: yesZhongguo shiyan zhenduanxue, 2014
目的研究血清胱抑素C(CysC)在高血压肾病早期的诊断价值。方法对305例高血压患者组及330例健康对照组,均进行血清CysC、肌酐(CREA)、尿素氮(BUN)三项指标检测。CysC检测采用兔疫透射比浊法,CREA及BUN检测均采用酶法。结果高血压患者组血清CysC阳性率(55.1%)明显高于其血清CREA(38.7%)及BUN(42.3 ...
季广厚
doaj  

Intermanufacturer assessment of diagnostic performance of angiogenic ratio vs glycosylated fibronectin in women with suspected pre‐eclampsia

open access: yesUltrasound in Obstetrics &Gynecology, Volume 64, Issue 5, Page 620-625, November 2024.
ABSTRACT Objective To compare the diagnostic performance of different manufacturers' immunoassays for the soluble fms‐like tyrosine kinase‐1 (sFlt‐1)‐to‐placental growth factor (PlGF) ratio with that of a point‐of‐care (PoC) test for glycosylated fibronectin (GlyFn) in women with suspected pre‐eclampsia (PE).
I. Y. M. Wah   +7 more
wiley   +1 more source

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