Results 11 to 20 of about 14,691 (187)

Social determinants of incidence, outcomes, and interventions of cardiovascular disease risk factors in American Indians and Alaska Natives

World Medical &Health Policy, Volume 15, Issue 4, Page 414-434, December 2023., 2023
Abstract Cardiovascular disease (CVD) is the leading cause of death among American Indians and Alaska Natives (AIANs). Despite copious research on CVD incidence and outcome discrepancies, a social determinants of health (SDOH) focused framework on CVD risk factors and health outcomes in AIAN populations has not been undertaken.
Eric Leung, Tassy Parker, Allyson Kelley, James C. Blankenship   +3 more
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Fatty acid β‐oxidation and mitochondrial fusion are involved in cardiac microvascular endothelial cell protection induced by glucagon receptor antagonism in diabetic mice 脂肪酸β‐氧化和线粒体融合参与胰高血糖素受体拮抗剂对糖尿病小鼠心脏微血管内皮细胞的保护作用

Journal of Diabetes, Volume 15, Issue 12, Page 1081-1094, December 2023., 2023
Highlights Glucagon receptor (GCGR) monoclonal antibody (mAb) improves cardiac function and attenuates microvascular damage in db/db mice. GCGR mAb ameliorates the oxidative stress of cardiac microvascular endothelial cells in diabetic mice. GCGR mAb counteracts the diabetes‐induced upregulation of carnitine palmitoyltransferase 1B, optic atrophy type ...
Peng Wang, Rui Wei, Xiaona Cui, Zongzhe Jiang, Jin Yang, Lingyun Zu, Tianpei Hong   +6 more
wiley   +1 more source

Protective effects of nattokinase against microvasculopathy and neuroinflammation in diabetic retinopathy 纳豆激酶对糖尿病视网膜病变微血管病变和神经炎症的保护作用

Journal of Diabetes, Volume 15, Issue 10, Page 866-880, October 2023., 2023
Highlights Nattokinase rescued endothelial dysfunction and pericyte loss in the diabetic retina. Nattokinase attenuated diabetes‐induced retinal inflammation and neurodegeneration. High mobility group box 1 signaling was involved in nattokinase‐mediated retinal protection.
Zijing Huang, Wai Kit Chu, Tsz Kin Ng, Shaolang Chen, Jiajian Liang, Chong‐Bo Chen, Yanxuan Xu, Biyao Xie, Shuping Ke, Qingping Liu, Weiqi Chen, Dingguo Huang   +11 more
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Impact on glucometric variables and quality of life of the advanced hybrid closed‐loop system in pediatric and adolescent type 1 diabetes 高级混合闭环系统对儿童和青少年1型糖尿病患者血糖指标和生活质量的影响

Journal of Diabetes, Volume 15, Issue 8, Page 699-708, August 2023., 2023
Highlights This study is the first to evaluate the efficacy of the closed‐loop system MiniMed 780G in children aged 6 to 17 years with type 1 diabetes previously receiving continuous subcutaneous insulin infusion and intermittent continuous glucose monitoring. This shows early results, with improvement in time in range and all hyperglycemia times, from
Alfonso Lendínez‐Jurado, Ana Gómez‐Perea, Ana B. Ariza‐Jiménez, Leopoldo Tapia‐Ceballos, Icía Becerra‐Paz, María F. Martos‐Lirio, Fernando Moreno‐Jabato, Isabel Leiva‐Gea   +7 more
wiley   +1 more source

Interventional metabology: A review of bariatric arterial embolization and endovascular denervation for treating metabolic disorders 介入放射学:代谢性疾病治疗手段的新补充

Journal of Diabetes, Volume 15, Issue 8, Page 665-673, August 2023., 2023
Highlights Interventional techniques offer novel therapeutic approaches for metabolic disorders such as obesity and type 2 diabetes mellitus, with advantages such as less invasiveness, fewer potential complications, and lower costs. By embolizing specific arteries feeding ghrelin‐producing cells, bariatric arterial embolization not only promotes weight
Zhi Wang, Dan‐Qi Zhu, Xiang‐Yun Zhu, De‐Chen Liu, Qing‐Yue Cao, Tao Pan, Qi Zhang, Xiao‐Chun Gu, Ling Li, Gao‐Jun Teng   +9 more
wiley   +1 more source

Use of basal insulin in the management of adults with type 2 diabetes: An Asia‐Pacific evidence‐based clinical practice guideline 使用基础胰岛素治疗成人2型糖尿病:亚太地区循证临床实践指南

Journal of Diabetes, Volume 15, Issue 6, Page 474-487, June 2023., 2023
Highlights This is a systematic review‐based clinical practice guideline. After internal and external review, two strong recommendations, six conditional recommendations, and one qualifying statement were made for insulin‐naive adult patients with type 2 diabetes.
Linong Ji, Yingying Luo, Yong Mong Bee, Jun Xia, Khue Thy Nguyen, Weigang Zhao, Liming Chen, Siew Pheng Chan, Chaicharn Deerochanawong, Soo Lim, Daisuke Yabe, Margaret McGill, Ketut Suastika, Xiaoying Li, Alice Pik Shan Kong, Wei Chen, Zhan Zhao, Chenchen Xu, Marisa Deodat, Xiaomei Yao   +19 more
wiley   +1 more source

Effects of neprilysin and neprilysin inhibitors on glucose homeostasis: Controversial points and a promising arena 脑啡肽酶和脑啡肽酶抑制剂对葡萄糖稳态的影响:一个有争议的观点和有前景的领域

Journal of Diabetes, Volume 15, Issue 5, Page 397-408, May 2023., 2023
Highlights Neprilysin (NEP) inhibitors may lead to beneficial effects through inhibition of NEP, which involves impairment of glucose homeostasis through modulation of insulin resistance and the development of pancreatic β cell dysfunction as observed in type 2 diabetes mellitus.
Faisal Holil AlAnazi, Hayder M. Al‐kuraishy, Ali I. Al‐Gareeb, Athanasios Alexiou, Marios Papadakis, Hanan A. Ogaly, Yousef Abud Alanazi, Hebatallah M. Saad, Gaber El‐Saber Batiha   +8 more
wiley   +1 more source

Mechanisms of diabetic foot ulceration: A review 糖尿病足溃疡发生机制综述

Journal of Diabetes, Volume 15, Issue 4, Page 299-312, April 2023., 2023
Highlights With the increase in the elderly population, diabetic foot ulcers (DFUs) severely affect human health and societies worldwide. They will pose significant medical, social, and socioeconomic challenges. Reviewing the existing studies on the pathogenesis of DFUs, most of them focus on clinical nursing and treatment.
Haibo Deng, Binghui Li, Qian Shen, Chenchen Zhang, Liwen Kuang, Ran Chen, SiYuan Wang, ZhiQiang Ma, Gongchi Li   +8 more
wiley   +1 more source

Evaluating the role of time in range as a glycemic target during short‐term intensive insulin therapy in patients with newly diagnosed type 2 diabetes 在新诊断的2型糖尿病患者中评估短期胰岛素强化治疗期间血糖达标时间作为血糖目标的作用

Journal of Diabetes, Volume 15, Issue 2, Page 133-144, February 2023., 2023
Highlights Whether time in range (TIR) during short‐term intensive insulin therapy (SIIT) was associated with treatment response to the therapy in patients with newly diagnosed type 2 diabetes was uncertain. TIRPIR, which was calculated according to the percentage of glucose points within predefined glycemic targets, was superior to TIR3.9–7.8mmol/L ...
Liehua Liu, Weijian Ke, Lijuan Xu, Hai Li, Juan Liu, Xuesi Wan, Jianbin Liu, Wanping Deng, Xiaopei Cao, Haipeng Xiao, Yanbing Li   +10 more
wiley   +1 more source

Changes in cardiovascular risk factors among children and young adults with type 1 diabetes during the COVID‐19 pandemic compared to previous years—Results from the German DPV registry COVID‐19大流行期间1型糖尿病儿童和年轻人心血管危险因素与往年相比的变化——来自德国糖尿病患者随访登记(DPV)的结果

Journal of Diabetes, Volume 15, Issue 1, Page 15-26, January 2023., 2023
Highlights Cardiovascular risk factors worsened during COVID‐19 in young people with type 1 diabetes. Blood pressure and atherogenic lipid levels were higher in 2020/2021 than expected. No further boost in 2020 and 2021 of the preexisting increase in body mass index‐SD score.
Alexander J. Eckert, Sabine Linke, Karl‐Otfried Schwab, Thekla von dem Berge, Eckhard Schönau, Ibrahim Duran, Axel Dost, Christine Joisten, Heike Bartelt, Katarina Braune, Joachim Rosenbauer, Reinhard W. Holl   +11 more
wiley   +1 more source