Results 21 to 30 of about 15,067 (136)

The efficacy of subcutaneous slow‐release melatonin implants in the prevention of canine flank alopecia recurrence is uncertain: A double‐blind, randomized, placebo‐controlled study

open access: yesVeterinary Dermatology, Volume 33, Issue 6, Page 553-558, December 2022., 2022
Background – Canine flank alopecia (CFA) is characterized by seasonally recurring noninflammatory, occasionally hyperpigmented alopecia predominantly in the thoracolumbar area. Previous studies suggest that reduced production of endogenous melatonin may play a role in the pathogenesis of this condition, and placebo‐controlled studies on the efficacy of
Millie U. M. Y. Verschuuren   +4 more
wiley   +1 more source

Glomerular cell cross talk in diabetic kidney diseases 糖尿病肾病中肾小球细胞间的相互作用

open access: yesJournal of Diabetes, Volume 14, Issue 8, Page 514-523, August 2022., 2022
Highlights Glomerular cell cross talk is essential for maintaining the glomerular filtration barrier. In‐depth exploration of intraglomerular signaling pathway changes during diabetic kidney disease may help discover new therapeutic targets. Abstract Diabetic kidney disease (DKD) is a severe microvascular complication of diabetes mellitus.
Ruixue Dong, Youhua Xu
wiley   +1 more source

Effects of SGLT2 inhibitors on patients with diabetic kidney disease: A preliminary study on the basis of podocyturia SGLT2抑制剂对糖尿病肾病患者的影响:基于尿足细胞的初步研究

open access: yesJournal of Diabetes, Volume 14, Issue 4, Page 236-246, April 2022., 2022
Highlights Diabetic kidney disease is a progressive disease with the pathology of glomerular damage and loss of podocytes. Sodium glucose cotransporter 2 inhibitors (SGLT2i) can be expected to decrease the amount of podocyte excretion. Male patients receiving SGLT2i have better diabetic kidney disease‐related parameters and podocyturia levels. Abstract
Emre Durcan   +13 more
wiley   +1 more source

Frederick Banting's observations leading to the potential for islet neogenesis without transplantation 弗雷德里克•班廷的发现形成了一种不需要移植就可能使胰岛新生的方法

open access: yesJournal of Diabetes, Volume 14, Issue 2, Page 104-110, February 2022., 2022
Highlights The observations of Frederick Banting, one century ago, may now lead to the generation of therapeutics that form new islets without the need for transplantation. Similar studies that were conducted by Banting of ligation of the pancreatic ducts in animal models of diabetes and pancreatitis have resulted in upregulation of the Reg gene ...
Claresa Levetan
wiley   +1 more source

Treatment of equine sarcoids using recombinant poxviruses expressing feline interleukin‐2

open access: yesVeterinary Dermatology, Volume 32, Issue 3, Page 283-e77, June 2021., 2021
Background – Interleukin (IL)‐2 stimulates antitumour immunity and is successfully used for the treatment of different neoplasias. Hypothesis/Objectives –Canarypox virus locally expressing feline IL‐2 is safe and can be used to treat equine sarcoids. Conclusions –Treatment of equine sarcoids with recombinant canarypox virus expressing feline IL‐2 seems
Johanna Loschelder‐Ostrowski   +4 more
wiley   +1 more source

MMC celebrating 6 years of experience and expansion 庆祝MMC六年的经验和壮大

open access: yes, 2022
Journal of Diabetes, Volume 14, Issue 5, Page 356-357, May 2022.
Itamar Raz
wiley   +1 more source

破裂颅内动脉瘤的超早期血管内介入治疗 [PDF]

open access: yes
Objective: To explore the clinic significance of endovascular treatment of  ruptured intracranial aneurysms in super-early stage. Methods: Endovascular treatment of 53 cases of ruptured intracranial aneurysms,including first ruptured in 42 cases and 11 ...
Hui, Rui, Lu, Wang-sheng, Wang, Peng
core   +2 more sources

缺血性卒中血管内治疗后时代:反桥接动脉溶栓研究进展(Research Progress on the Effect of Intra-Arterial Thrombolysis on Improving Functional Outcomes Following Successful Endovascular Treatment)

open access: yesZhongguo cuzhong zazhi
血管内治疗作为急性大血管闭塞性缺血性卒中的一线治疗措施,能实现80%以上的血管再通率。但血管内治疗后无效再通问题突出,约50%的患者无法获得良好功能预后。无复流现象和早期动脉再闭塞是血管内治疗后无效再通的核心机制,且两者均与术后血栓负荷密切相关。血管内治疗反桥接动脉溶栓可清除残余血栓并改善脑组织的微循环灌注,有望进一步改善急性大血管闭塞性缺血性卒中患者的功能预后。2022年,机械取栓治疗急性卒中血栓栓塞药物优化(chemical optimization of cerebral embolectomy
沈柯佳,王利圆,熊云云(SHEN Kejia, WANG Liyuan, XIONG Yunyun)
doaj   +1 more source

金纳多治疗烟雾病所致缺血性卒中个案报道 A Case Report on the Treatment of Ischemic Stroke Caused by Moyamoya Disease with Ginaton REN Xiaojia, LIU Guanjie, HAO Wenqiang

open access: yesZhongguo cuzhong zazhi, 2023
烟雾病是一种原因不明的慢性血管性疾病,其特征为颅内血管进行性狭窄、闭塞及异常血管网形成。临床可表现为缺血性或出血性卒中、头痛、癫痫等,治疗包括外科手术及药物治疗。本文通过对1例烟雾病所致缺血性卒中患者治疗前后的临床疗效比较并观察不良反应的发生情况,探讨金纳多序贯治疗的疗效及可行性,以供临床参考。 Abstract: Moyamoya disease is a chronic vascular disease of unknown cause, characterized by ...
任晓佳, 刘关杰, 郝汶强
doaj   +1 more source

Assessment of the Image Quality of Virtual Non-Contrast Dual-energy CT Liver Scans Using Both PSNR and SSIM Methods [PDF]

open access: yes
The purpose of this study was to investigate the feasibility of replacing true non-contrast (TNC) dual-energy computed tomography (DECT) images with virtual non-contrast (VNC) DECT images by comparing their quality on the basis of both the peak signal-to-
Jiankui MU   +7 more
core   +1 more source

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