Results 11 to 20 of about 13,203 (122)

NIR‐Responsive Nano‐Integrated Magnesium Phosphate Cement Promotes Bone Regeneration via Osteoblast‐Exosome‐Osteoclast Crosstalk

open access: yesRare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT The limited osteogenic capacity of magnesium phosphate cement (MPC) has constrained its biomedical applications, underscoring the necessity to develop MPC with enhanced physical properties and bone‐forming capabilities. In this study, a multifunctional MPC system was developed by incorporating zoledronic acid‐loaded near‐infrared (NIR ...
Bin Wang   +8 more
wiley   +1 more source

Developing a Linguistically Valid Japanese Version of the Chronic Pain Attribution Scale: Translation and Cultural Adaptation Process

open access: yesNeuropsychopharmacology Reports, Volume 45, Issue 4, December 2025.
This study reports the development and linguistic validation of the Japanese version of the Chronic Pain Attribution Scale. The tool captures culturally nuanced beliefs about chronic pain causes and provides a foundation for research on treatment responses in Japanese‐speaking populations.
Keiko Yamada   +8 more
wiley   +1 more source

女性高血压患者绝经前后及绝经年限与血脂水平关系探讨 [PDF]

open access: yes, 2005
目的探讨女性高血压患者绝经前后及绝经年限与血脂变化的关系。方法女性高血压患者131例,分绝经前组(34例)及绝经后组(97例),测晨起空腹静脉血中甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C),进行组间比较,并分析绝经年限与血脂水平的相关性。并与73例健康对照组比较。结果绝经前高血压组TC、LDL-C〔(5.27±0.47)mmol/L和(3.50±0.45)mmol/L〕显著高于对照组〔(4.33±0.70)mmol/L和(2.67±0.50 ...
周乃珍, 张作伟, 陈治卿
core  

Review of additively manufactured zinc alloys by laser powder bed fusion for biomedical applications

open access: yesRare Metals, Volume 44, Issue 11, Page 8262-8291, November 2025.
Graphical abstract AbstractZinc (Zn) and its alloys have emerged as promising candidates for biomedical materials, owing to their controlled degradation kinetics, intrinsic biocompatibility, and the release Zn2+ ions which are known to promote bone regeneration and tissue healing.
Xuan Yang   +5 more
wiley   +1 more source

抗中性粒细胞胞浆抗体相关性血管炎合并真菌感染的2例病例报道

open access: yesZhongguo shiyan zhenduanxue, 2020
ANCA相关性血管炎可累及全身,并且诊断血管炎通常很困难,因为其临床症状与常见的传染病和其他炎症性疾病十分相似。研究表明,外周血单个核细胞中的趋化因子受体8(CCR8)增强了MPO-ANCA相关血管炎的活性,可能是ANCA相关性血管炎鉴别活动性血管炎和感染性炎症的有用标志物[1]。免疫抑制剂是其治疗的主体,分为缓解诱导疗法和维持疗法。糖皮质激素与环磷酰胺仍然是治疗普遍性疾病的共识指南中的标准治疗方法。
杨佳慧, 张欢, 徐晓华
doaj  

螺内酯联合贝前列腺素钠对2型糖尿病肾病患者肾功能的影响 [PDF]

open access: yes, 2019
目的探讨贝前列素钠联合螺内酯治疗2型糖尿病肾病的临床研究。方法选取2型糖尿病肾病患者94例,按照随机数字表法随机分为观察组47例与对照组47例。对照组采取单用贝前列素钠治疗,观察组在对照组基础上结合螺内酯联治疗。比较两组治疗前后尿素氮、血肌酐、24 h尿微量清蛋白(m ALB)和肾小球滤过率(GFR)变化。结果观察组总有效率(93.62%)高于对照组(72.34%)(P
张美玲   +4 more
core  

Linarin Ameliorates Aortic Endothelial Dysfunction in Diabetic Mice by Targeting Intelectin 1 [PDF]

open access: yes
This study utilized streptozotocin to create a diabetic mouse model to investigate the role of intelectin 1 (ITLN1) in repairing the aortic endothelial cells of diabetic mice, and it also identified linarin as dietary ITLN1 agonist and evaluated the ...
LI Zicheng, MAO Aiqin, SHI Xiaoming, HE Dongxu
core   +1 more source

人工气候箱在“六淫”研究中的应用 [PDF]

open access: yes, 2014
“六淫“的发生与气候密切相关,人工气候箱可以模拟出自然界可能出现的各种气候类型,为“六淫“实验研究的最重要手段之一,已在风、寒、湿、燥邪等研究中取得一定成果。然而由于气候对人体的影响规律尚不明确,所以研究中还存在同种邪气气候箱条件设置各异、动物在气候箱放置时间各异等问题,也是“六淫“研究今后要深入探讨的问题。认为随着人工气候箱的发展,可以模拟出更精确、复杂的气候环境,可望在“六淫“和其他气候相关科研中发挥更大作用。国家自然科学基金资助项目(81302876); 福建省自然科学基金资助项目 ...
何宽其   +4 more
core  

一种新的心血管活性肽:Salusins

open access: yesZhongguo shiyan zhenduanxue, 2011
心血管系统合成和分泌多种小分子的生物活性物质,如血管活性多肽、生物活性氨基酸、细胞因子生长因子和一氧化碳、硫化氢等气体信号分子。这些生物活性分子具有分子量小、种类繁多 ...
张婧, 冷吉燕
doaj  

靶向血管内皮生长因子受体2的sKDR抑制血管内皮细胞生长和血管生成的研究

open access: yesZhongguo shiyan zhenduanxue, 2020
目的研究可溶性血管内皮生长因子受体2(sKDR)对人脐静脉内皮细胞(HUVEC)及血管形成的抑制作用。方法利用RT-PCR方法提取KDR胞外血管内皮生长因子(VEGF)结合区编码基因,构建真核分泌型表达质粒PQE40-KDR,即可溶性血管内皮生长因子受体sKDR,脂质体法转染HUVEC,经G418抗性压力筛选稳定转染细胞株。ELISA法检测细胞上清VEGF结合活性,筛选稳定表达sKDR的HUVEC。RT-PCR检测细胞KDR蛋白表达水平,比色法和鸡胚尿囊膜(CAM ...
郑红淑   +5 more
doaj  

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