Results 51 to 60 of about 2,209 (105)

狭缝引导配体1-3’非翻译区抑制心肌成纤维细胞纤维化表型的作用

Zhongshan Daxue xuebao. Yixue kexue ban
目的研究狭缝引导配体1（Slit1）的3’非翻译区序列部分片段（Slit1-3’UTR）对心肌成纤维细胞的纤维化表型的调节作用和可能机制。方法利用腺病毒介导在ICR乳小鼠心肌成纤维细胞（mCFs）中过表达Slit1-3’UTR 1526nt序列（Slit1-3’UTR 1526nt），使用蛋白质免疫印迹技术评估mCFs中胶原Iα1/（COL1A1）、胶原IIIα1/（COL3A1）、α平滑肌肌动蛋白（α-SMA）等纤维化相关基因的表达水平，结合EdU和Trans ...
王娅, 伍华燕, 高原, 吴茹诗, 关佩莹, 李晖, 方俊涛, 单志新   +7 more
doaj   +2 more sources

[β‑blockers after percutaneous coronary intervention does not reduce risks of all-cause mortality or major adverse cardiovascular events in patients with stable coronary artery disease]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Gao X, Xiao J, Feng N, Guo C, Cao L, Zhang C, Zhang Y, Han T.   +7 more
europepmc   +1 more source

[POEMS syndrome misdiagnosed as systemic sclerosis: A case report]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Liang J, Zhang X, Yao H.
europepmc   +1 more source

α７ｎＡＣｈＲ激动剂对血管紧张素Ⅱ诱导的心肌成纤维细胞增殖和胶原合成的影响及其分子机制

Zhongshan Daxue xuebao. Yixue kexue ban, 2016
摘 要： 【目的】 探讨α７烟碱乙酰胆碱受体（α７ ｎＡｃｈＲ）激动剂对血管紧张素Ⅱ（ＡｎｇⅡ）诱导的心肌成纤维细胞增殖和胶原合成的影响及其分子机制。【方法】 培养出生２～３ｄ大鼠心肌成纤维细胞（ＣＦ），取传代２ ～ ４代细胞，分为①空白对照组（ｃｏｎｔｒｏｌ）；②模型组（ＡｎｇⅡ１０－７ ｍｏｌ／Ｌ）；③ＡＣｈ预处理组：ＡＣｈ ＋ ＡｎｇⅡ组（ＡＣｈ １０－４ ｍｏｌ／Ｌ ＋ ＡｎｇⅡ１０－７ ｍｏｌ／Ｌ）；④α７ｎＡＣｈＲ激动剂组：α７ｎＡＣｈＲ激动剂＋ ＡｎｇⅡ组（ＰＮＵ－２８２９８７ ５ ...
doaj  

[Acquired factor ⅩⅢ deficiency with FⅩⅢ inhibitor secondary to rheumatoid arthritis: a case report]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Zhu BC, Cai HC, Zhang Y, Wang L, Wang W.
europepmc   +1 more source

[Chinese guideline on the diagnosis and treatment of adult primary immune thrombocytopenia (2025)]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Thrombosis and Hemostasis Group, Chinese Society of Hematology, Chinese Medical Association.   +2 more
europepmc   +1 more source

钙蛋白酶对血管紧张素Ⅱ诱导的心肌成纤维细胞增殖及纤维化模型的影响

Zhongshan Daxue xuebao. Yixue kexue ban, 2013
【目的】 研究钙蛋白酶在血管紧张素ＩＩ（Ａｎｇ ＩＩ）诱导的心肌纤维化中的作用及作用机制。【方法】 原代培养ＳＤ大鼠心肌成纤维细胞（ＣＦ），取传代２－４代细胞，，预先给予不同浓度ｃａｌｐａｉｎ抑制剂ＰＤ１５０６１６，观察对Ａｎｇ ＩＩ诱导致纤维化模型的影响。实验分为空白对照组（ｃｏｎｔｒｏｌ）、模型组（Ａｎｇ ＩＩ）、低浓度给药组（Ａｎｇ ＩＩ＋ ＰＤ１５０６１６＿５ μｍｏｌ／Ｌ）、高浓度给药组（Ａｎｇ ＩＩ＋ ＰＤ１５０６１６＿１０ μｍｏｌ／Ｌ）。Ｅｄｕ检测ＣＦ增殖，Ｗｅｓｔｅｒｎ ...
doaj  

[Advancing the development of hematology care units to enhance hematology‑specific critical care capacity]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Fan SJ, Li HT, Zhang X.
europepmc   +1 more source

[Risks, mechanisms, and prevention strategies for cerebrovascular diseases in lunar astronauts under deep]. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban
Tang L, Tang Q, Li Y, Wang L, Zhang F, Zhang X, Liu R, Zhang L.   +7 more
europepmc   +1 more source

[Impact of elevated arterial blood pressure on bioprosthetic valve calcification and failure after transcatheter aortic valve replacement]. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban
Sheng W, Zhu Q, Dai H, Zhou D, Liu X.
europepmc   +1 more source