Zhongshan Daxue xuebao. Yixue kexue ban, 2006 【目的】观察大剂量血管紧张素受体拮抗剂单独、或联合血管紧张素转换酶抑制剂治疗慢性肾小球肾炎及糖尿病肾病的疗效和安全性。【方法】40例病人按随机数字表分2组，缬沙坦组（n=20）服用缬沙坦（valsartan）320mg／d，联合组（n=20）服用盐酸贝拉普利（benazepril hydrochlofide）20mg／d联合缬沙坦160mg／d，疗程6个月。观察24h尿蛋白、血清肌酐、血压及血钾变化及不良反应情况。【结果】6个月缬沙坦组24h尿蛋白由治疗前（2．2±1．5）g／d降到（0．7±0．7）g／
李超 +4 more
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抑制 NAD(P)H 氧化酶表达和活性对大鼠糖尿病肾病的影响
Zhongshan Daxue xuebao. Yixue kexue ban, 2004 【目的】 探讨NAD(P)H氧化酶在糖尿病肾病发病中的作用和防治方法?【方法】 链脲佐菌素(STZ)诱导的大鼠糖尿病模型随机分为糖尿病组NAD(P)H氧化酶抑制剂apocynin治疗组(0.2 g·kg-1·d-1)和血管紧张素转换酶抑制剂福辛普利治疗组(10 mg· kg-1· d-1),疗程8周?用RT-PCR检测肾NAD(P)H氧化酶亚基p22phox mRNA表达;组织病理学检查观察肾病变程度;测定血肌酐(Scr)?内生肌酐清除率(Ccr)?24 h尿蛋白排泄量?肾质量指数等?【结果 ...
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Zhongshan Daxue xuebao. Yixue kexue ban, 2014 【目的】 研究ＩｇＡ肾病（ＩｇＡＮ）患儿血浆氧化应激水平的变化及其与临床病理的关系，探讨血管紧张素转换酶抑制剂（ＡＣＥＩ）对ＩｇＡＮ患儿血浆氧化应激水平的影响。【方法】３８例ＩｇＡＮ患儿根据按临床表现分为３组：血尿蛋白尿（ＨＰ）组（１４例），急性肾炎（ＡＧＮ）组（７例），肾病综合征（ＮＳ）组（１７例）；按病理分级分为３组：病理Ⅲ级组（２２例），病理Ⅳ级组（１０例），病理Ⅴ级组（６例）；按初次就诊时是否曾接受激素和（或）免疫抑制剂治疗分为２组：初发组（２８例），非初发组（１０例）；其中 ...
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Serum Uric Acid and Long-term Prognosis in Patients with Acute Myocardial Infarction [PDF]
, 2022 BackgroundIt is still controversial whether or not serum uric acid, a key risk for coronary heart disease, is significantly associated with prognosis of acute myocardial infarction (AMI) .
CHEN Qiang, CHEN Yingzhong, CUI Caiyan, JIANG Xinglin, ZHU Feng, LI Siyi, ZHANG Yumei, YE Tao, CAI Lin
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Clinical Effect of Early Application of Self-prescribed Yiqihuoxue Decoction on Prevention and Treatment of Depressive Symptoms after Acute Myocardial Infarction [PDF]
, 2022 BackgroundPost-acute myocardial infarction (AMI) patients are prone to depression and other negative emotions. Current treatment for post-AMI patients with depression is anti-myocardial infarction treatment plus anti-depression treatment, in the ...
WANG Mengxi, LIU Qian, SHEN Le, CHEN Xiaohu
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Characteristics and Prognosis of Herat Failure with Improved Ejection Fraction [PDF]
, 2022 BackgroundLeft ventricular ejection fraction (LVEF) is often used to classify heart failure (HF) . Some HF patients were observed to have improved ejection fraction after treatment, thus giving rise to the concept of HF with improved EF (HFimpEF ...
SU Kangkang, WANG Yan, WANG Lili, CHEN Shuxia, GU Jian
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长效降压药联合他汀类降脂药治疗高血压病的疗效观察 [PDF]
, 2018 目的观察长效降压药联合他汀类降脂药治疗高血压病的临床效果。方法选取医院收治的高血压病患者132例,随机分为对照组和观察组,每组66例。对照组使用长效降压药治疗,观察组使用长效降压药联合他汀类降脂药治疗。比较2组治疗前后血压和血脂变化,出院后脑血管意外事件发生率。结果治疗后,2组收缩压、舒张压较治疗前均降低,且观察组收缩压、舒张压低于对照组 ...
洪丽娜
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Association between Subclinical Hypothyroidism and Cardiac Autonomic Neuropathy in Type 2 Diabetes Mellitus [PDF]
, 2022 BackgroundCardiac autonomic neuropathy (CAN) is a common and severe chronic diabetic complication, whose association with thyroid function has rarely been reported.ObjectiveTo investigate the association between subclinical hypothyroidism and CAN in type
ZHAO Lei, LI Ruqiang, YUAN Mingxia
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Isolation, Structural Identification and in Vitro Activity Evaluation of Angiotensin-Converting Enzyme Inhibitory Peptides from Moringa oleifera Seeds [PDF]
, 2023 In this study, angiotensin-converting enzyme (ACE) inhibitory peptides from an enzymatic hydrolysate of Moringa oleifera seeds were separated by sequential ultrafiltration and ion exchange chromatography.
ZHONG Yuwang, XU Wanli, FAN Yaozhu, LI Yiyan, WANG Xuefeng
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Meta-analysis of Curative Effects and Safeties of Baraclude Versus Other Nucleoside Drugs for Treatment of HBeAg-positive Chronic Hepatitis B [PDF]
, 2017 目的：评价博路定和其他抗乙肝病毒核苷酸类药物对核苷初治的乙型肝炎 e 抗原（HBeAg）阳性慢性乙型肝炎（CHB）患者的疗效和安全性。方法：计算机检索 PubMed、Mestre、中国期刊全文数据库（CNKI）、中文科技期刊数据库（VIP）、万方数据库（建库至2015年10月）公开发表的有关博路定和其他抗乙肝病毒核苷酸类药物对核苷初治的 HBeAg 阳性 CHB 患者疗效的随机对照试验（RCTs），并追查已获文献的参考文献。由两名研究者独立筛选文献，提取数据，按照改良后 Jadad 评分标准进行质量评价。
严国鸿 +5 more
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