摘 要: 【目的】 研究体外实验中,抗血小板药物替格瑞洛对原代小鼠树突状细胞(DC)摄取吞噬抗原以及促进T细胞增殖能力的影响? 【方法】 以RT-PCR?Western-Blotting方法测定细胞P2Y12受体基因和蛋白水平表达?实验分为空白对照组?单纯ADPβS刺激组?替格瑞洛+ADPβS组?以FITC标记葡聚糖(FITC-Dextran)作为荧光抗原检测DC吞噬抗原能力;将DC负载卵清蛋白(OVA),与OT-2转基因鼠脾脏T淋巴细胞共培养4 d,流式细胞仪检测荧光染料CFSE标记T细胞增殖情况? 【
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[Biomechanical advantages of personalized Y-shaped plates in treatment of distal humeral intra-articular fractures]. [PDF]
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应用ATPase组化法及TEM法对皮肤癣菌病患者表皮郎格罕细胞的观察
本文应用ATPase组化方法首次对30例皮肤癣菌病患者皮损表皮及70例对照者相应部位表皮作了郎格罕细胞(LC)观察,并对其中3例患者及1例对照者表皮LC作了透射电镜(TEM)观察。结果发现患者表皮LC形态改变、数量减少或消失及细胞超微结构受损;且上述改变程度随病变范围扩大及病程延长而加重。本文首次提出LC与皮肤癣菌病的免疫病理改变有密切关系,可能皮肤癣菌的入侵使表皮LC受损,从而干扰了T淋巴细胞诱导的机体对病原体的清除功能。本文还讨论了两种方法的注意点。
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[<i>Tiaozhou Ziyin</i> recipe for treatment of premature ovarian insufficiency: efficacy, safety and mechanism]. [PDF]
Tang P+6 more
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[Stroke-p2pHD: Cross-modality generation model of cerebral infarction from CT to DWI images]. [PDF]
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Lian Q, Xiao Y, Xiao Y, Cao Z, Cui G.
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