Results 1 to 10 of about 3,657 (120)

Autophagy in the retinal neurovascular unit: New perspectives into diabetic retinopathy. [PDF]

J Diabetes, 2023
HighlightsAutophagy is closely related to retinal neurovascular units in diabetes retinopathy. Different cells participate in the occurrence and development of diseases through autophagy, and targeted autophagy may be a new direction of treatment in the future. Emphasized the close relationship between diabetic retinopathy (DR) and autophagy Summarized
Yang X, Huang Z, Xu M, Chen Y, Cao M, Yi G, Fu M.   +6 more
europepmc   +2 more sources

A stratified analysis of a deep learning algorithm in the diagnosis of diabetic retinopathy in a real-world study. [PDF]

J Diabetes, 2022
Highlights Our deep learning algorithm (DLA)‐based diabetic retinopathy (DR) grading software showed excellent performance in detecting referable DR, especially in patients with type 1 diabetes and diabetic nephropathy who were prone to DR. The DLA showed consistent performance in the detection of referable DR across different subgroups stratified by ...
Li N, Ma M, Lai M, Gu L, Kang M, Wang Z, Jiao S, Dang K, Deng J, Ding X, Zhen Q, Zhang A, Shen T, Zheng Z, Wang Y, Peng Y.   +15 more
europepmc   +2 more sources

早产儿视网膜病变治疗药物研究进展 [PDF]

浙江大学学报. 医学版
早产儿视网膜病变（ROP）是威胁早产儿视力的视网膜血管增殖性疾病。多种新型药物通过靶向与血管内皮生长因子（VEGF）相关信号通路［如PI3K/Akt、低氧诱导因子（HIF）-1α/VEGF等］、氧化应激、肿瘤坏死因子（TNF）-α和Notch等信号通路在ROP的治疗中展现出潜力。普萘洛尔、胰岛素样生长因子-1、塞来昔布通过PI3K/Akt信号通路减少病理性新生血管生成；雷公藤红素、褪黑素通过HIF-1α/VEGF信号通路抑制视网膜病变；脂联素通过增强内皮型一氧化氮合酶活性缓解氧化应激损伤 ...
谢 彦茜, 郑 穗联, 杨 晖
doaj   +2 more sources

Computerized nailfold video‐capillaroscopy in type 2 diabetes: A cross‐sectional study on 102 outpatients 计算机化甲襞视频毛细血管镜在2型糖尿病中的运用: 对102例门诊患者的横断面研究

Journal of Diabetes, Volume 15, Issue 10, Page 890-899, October 2023., 2023
Highlights Patients with type 2 diabetes (T2D) are prone to developing chronic diabetes‐related complications at the microvascular and macrovascular levels. The Computerized Nailfold Video‐Capillaroscopy (CNVC) provides specific information on both quantitative and qualitative characteristics of microvasculature at the level of fingers.
Giuseppe Lisco, Vincenzo Triggiani
wiley   +1 more source

The use of nomogram for detecting mild cognitive impairment in patients with type 2 diabetes mellitus 使用列线图筛查2型糖尿病轻度认知障碍

Journal of Diabetes, Volume 15, Issue 5, Page 448-458, May 2023., 2023
Highlights Almost one in three patients with type 2 diabetes mellitus suffered from mild cognitive impairment. Age, marital status, household income, diabetes duration, diabetic retinopathy, anxiety, and depression were associated with mild cognitive impairment.
Rehanguli Maimaitituerxun, Wenhang Chen, Jingsha Xiang, Yu Xie, Atipatsa C. Kaminga, Xin Yin Wu, Letao Chen, Jianzhou Yang, Aizhong Liu, Wenjie Dai   +9 more
wiley   +1 more source

Sleeve gastrectomy improved microvascular phenotypes from obesity cohort, detected with optical coherence tomography angiography 通过光学相干断层扫描血管成像检测发现袖状胃切除术改善肥胖队列的微血管表型

Journal of Diabetes, Volume 15, Issue 4, Page 313-324, April 2023., 2023
Highlights Different microvascular phenotypes were detected by noninvasive optical coherence tomography angiography (OCTA) in metabolically healthy obesity and metabolic syndrome patients. Baseline blood pressure and insulin status may be key determinants for vascular benefit from bariatric surgery.
Yaying Chen, Yanyang Liu, Lin Cong, Ailin Liu, Xiangyuan Song, Wenting Liu, Rong Hua, Qiwei Shen, Yikai Shao, Yiwen Xue, Qiyuan Yao, Yuyan Zhang   +11 more
wiley   +1 more source

Assessment of subclinical left ventricular systolic dysfunction in patients with type 2 diabetes: Relationship with HbA1c and microvascular complications 2型糖尿病患者亚临床左心室收缩功能障碍的评估:与糖化血红蛋白和微血管并发症的关系

Journal of Diabetes, Volume 15, Issue 3, Page 264-274, March 2023., 2023
Highlights In asymptomatic type 2 diabetic patients with preserved left ventricular ejection fraction, a negative correlation of glycated hemoglobin with subclinical left ventricular systolic dysfunction was revealed. Furthermore, glycated hemoglobin may make prognostic significance for the progression of myocardial damage. Abstract Background We aimed
Yanyan Chen, Ying Zhang, Yi Wang, Shengjun Ta, Min Shi, Yingni Zhou, Mengying Li, Jianfang Fu, Li Wang, Xiangyang Liu, Zuowei Lu, Liwen Liu, Zeping Li, Jie Zhou, Xiaomiao Li   +14 more
wiley   +1 more source

Nailfold capillaroscopy and deep learning in diabetes 甲襞毛细血管镜检测与深度学习在糖尿病中的应用

Journal of Diabetes, Volume 15, Issue 2, Page 145-151, February 2023., 2023
Highlights Nailfold capillary images were obtained by performing nailfold video capillaroscopy in 120 adult patients with and without diabetes. Over 5000 photographs were analyzed using machine‐learning approaches, and these models were clearly able to distinguish people based on diabetes status.
Reema Shah, Jeremy Petch, Walter Nelson, Karsten Roth, Michael D. Noseworthy, Marzyeh Ghassemi, Hertzel C. Gerstein   +6 more
wiley   +1 more source

Study of the correlation between ApoB/ApoA1 and vitreous hemorrhage secondary to diabetic retinopathy [PDF]

, 2023
Objective To investigate the correlation between ApoB/ApoA1 and vitreous hemorrhage （VH） secondary to diabetic retinopathy （DR）. Methods 187 patients with DR from August 2021 to December 2022 were recruited and divided into VH （n=96） and non-VH groups （n=
Dan Yujiao, Zhang Ling, Chen Bin
core   +1 more source

Lipid variability and risk of microvascular complications in Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial: A post hoc analysis 控制糖尿病心血管风险的行动(ACCORD)试验中的血脂变异性和微血管并发症风险:一项事后分析

Journal of Diabetes, Volume 14, Issue 6, Page 365-376, June 2022., 2022
HighlightsAssociation of lipid variability with diabetic microvascular complications. Abstract Background Greater lipid variability may cause adverse health events among diabetic patients. We aimed to examine the effect of lipid variability on the risk of diabetic microvascular outcomes among type 2 diabetes mellitus patients.
Daniel Nyarko Hukportie, Fu‐Rong Li, Rui Zhou, Jia‐Zhen Zheng, Xiao‐Xiang Wu, Meng‐Chen Zou, Xian‐Bo Wu   +6 more
wiley   +1 more source