Results 21 to 30 of about 10,351 (165)
高血压合并脑梗死患者BPV与IMT、NT-pro-BNP、神经及认知功能的关系
Zhongguo shiyan zhenduanxue, 2022 目的 分析高血压合并脑梗死患者血压变异性(BPV)与颈动脉内膜-中层厚度(IMT)、N-末端脑钠肽前体(NT-pro-BNP)、神经及认知功能的关系。方法 回顾性分析2018年9月～2021年9月西宁市第二人民医院收治的高血压合并脑梗死患者156例、同期高血压患者50例及健康体检者50例的BPV指标、超声测量的IMT及血清NT-pro-BNP水平。采用美国国立卫生院神经功能缺损评分(NIHSS)及简明精神状态量表(MMSE)评估患者神经及认知功能，依据不同程度分组并比较患者BPV ...
薛世磊, 孙永全
doaj
Zhongguo cuzhong zazhi, 2019 目的 探讨腔隙性脑梗死（lacunar infarction，LI）认知功能障碍与颈动脉粥样硬化性斑块的关系。 方法 回顾性分析2017年1月-2018年11月就诊于海淀医院神经内科的符合LI诊断标准的患者171例，按照蒙特利尔认知评估量表（Montreal cognitive assessment scale，MoCA）评分分为认知功能障碍组和非认知功能障碍组，对颈动脉动脉粥样硬化性斑块与认知功能障碍之间的关系进行Logistic多因素回归分析。 结果 调整潜在混杂因素后 ...
杨兴东，曾一君，唐晓梅，冯研，史冬梅，刘磊，于逢春
doaj +1 more source
Investigation of the association between adult intelligence and Apolipoprotein E genotype in the young Chinese Han population [PDF]
, 2015 载脂蛋白E（ApolipoproteinE）在脂质代谢及分布中具有重要作用。载脂蛋白E基因具有多态性，包含了APOEɛ2、APOEɛ3和APOEɛ4三种。其中，ɛ4等位基因是引起迟发型阿尔茨海默病（Late-onsetAlzheimer’sDisease）最重要的危险因素。尽管许多研究表明在老年人中APOE基因的多态性与认知功能密切相关，但其对青年人认知功能的影响研究非常少，并且有限的研究结果存在争议性。为了进一步探讨APOE基因多态性对青年人认知功能的影响 ...
魏孜辰
core
Taxonomic and functional diversity of urban bees of the world
Conservation Biology, EarlyView.Abstract Bees play a pivotal role in terrestrial environments. Urbanization can affect these organisms and the ecosystem services they provide. However, knowledge of the global diversity of urban bees is limited. Thus, we summarized data on urban bee species identities and occurrences; compared distributions of all bees with those found in urban ...
João C. F. Cardoso +10 more
wiley +1 more source
Zhongguo cuzhong zazhi, 2018 血管性认知障碍（vascular cognitive impairment，VCI）包括从轻度认知功能受损到痴呆的 各种程度的认知功能受损，伴随着脑结构和脑功能的变化。磁共振成像（magnetic resonance imaging， MRI）作为一种广泛应用的诊断工具，可以无创地观察患者脑组织的变化。结合自动分割算法，对采集 到的MRI数据进行分类，在识别血管性认知障碍方面具有广泛的应用前景。本文对近年来MRI在诊断 血管性认知障碍方面的研究进展和新技术进行综述。 Abstract ...
战扬，崔文韬，韩璎
doaj +1 more source
From Clueless to Confident: How ChatGPT Transforms Academic Writing in Chinese as a Second Language
International Journal of Applied Linguistics, Volume 36, Issue 2, Page 1235-1251, May 2026.ABSTRACT Generative artificial intelligence (GenAI) has demonstrated its potential to enhance the quality of second‐language (L2) academic writing. This study used a qualitative approach comprising analysis of ChatGPT usage‐history screenshots, written assignments, and semi‐structured interview data on students’ use of GenAI in their L2 Chinese ...
Lanfang Sun +4 more
wiley +1 more source
Multi-modal fMRI study on brain structure and function in different factors induced rat chronic obstructive pulmonary disease [PDF]
, 2015 慢性阻塞性肺病（chronicobstructivepulmonarydisease，COPD）脑结构和功能的异常在近些年受到了越来越多的研究关注。先前的神经影像学研究已经发现COPD伴随着白质完整性的损害和灰质的丢失，以及功能连接网络的异常。但是吸烟和非吸烟(如慢性肺部炎症)诱导的COPD病人脑部形态学和功能的异同，以及吸烟和感染因素的综合诱导是否加重了脑损害尚不清楚。致病因素和COPD病人脑部异常的特征性对应关系仍待进一步的探究 ...
陈骥
core
Conservation Biology, Volume 40, Issue 2, April 2026.Abstract There exists a growing suite of technologies that support significant and exciting progress in biodiversity conservation and research. Citizen scientist participation is common in this research and often focuses on data collection and labeling.
Joycelyn Longdon +5 more
wiley +1 more source
High-performance liquid chromatography-mass spectrometry-based acetylcholinesterase assay for the screening of inhibitors in natural medicinal plants [PDF]
, 2016 酶是治疗多种疾病的重要靶标，乙酰胆碱酯酶（AChE）的抑制剂是现阶段治疗阿尔兹海默症（AD）最有效的一类药物。从天然产物中寻找适宜患者长期服用、毒副作用小、作用面广等优点的乙酰胆碱酯酶抑制剂（AChEIs）受到了科研工作者的广泛关注。本论文以AChE作为药物靶标，构建基于高效液相色谱-质谱联用技术（HPLC-MS）的在线生物活性检测方法，发展集分离纯化、结构确证和活性筛选于一体的活性导向天然产物研究方法，用来寻找和发现天然药用植物中潜在的AChEIs候选化合物 ...
刘静兰
core
Veterinary Dermatology, Volume 37, Issue 2, Page 293-305, April 2026.Background: Canine atopic dermatitis (cAD) is a common, chronic skin condition characterised by epidermal barrier dysfunction, immune dysregulation and cutaneous dysbiosis. While “emollient plus” formulations are widely used in human atopic dermatitis, their role in cAD remains underexplored. Hypothesis/Objectives: To evaluate the clinical efficacy and
Beatriz Fernandes +8 more
wiley +1 more source