Results 31 to 40 of about 99,626 (185)
血清学标志物甲胎蛋白、PIVKA-Ⅱ和磷脂酰肌醇蛋白聚糖3联合诊断肝癌的meta分析
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences目的 探讨血清生物标志物甲胎蛋白（AFP）、维生素K缺失或拮抗剂Ⅱ诱导的蛋白质（PIVKA-Ⅱ）和磷脂酰肌醇蛋白聚糖3（GPC-3）单独或联合用于肝细胞癌（以下简称肝癌）诊断的价值。 方法 检索PubMed、Web of Science、Embase三个数据库，收集2002年以来发表的AFP、PIVKA-Ⅱ和GPC-3单独或联合用于诊断肝癌的文献。根据纳入和排除标准筛选文献并提取相关数据。利用诊断准确性研究的质量评价（QUADAS）检查表对纳入的文献进行质量评价，并采用Meta DiSc软件 ...
Hongliang Song +6 more
semanticscholar +1 more source
Biomimetic Metallopeptidases for Biomedical Applications: From Modular Design to Disease Treatment
Rare Metals, Volume 45, Issue 5, May 2026.ABSTRACT Biomimetic metallopeptidases, as an emerging class of artificial enzyme systems, have demonstrated tremendous application potential in the biomedical field in recent years. Their core design principle is to rationally control amino acid composition and three‐dimensional conformation so that programmable peptide sequences can efficiently ...
Ke Ma, Ke‐Zheng Chen, Sheng‐Lin Qiao
wiley +1 more source
Zhongguo shiyan zhenduanxue, 1998 “没有正确的诊断，便没有正确的治疗”是每位临床医师都熟悉的格言。诊断包括临床诊断和病理诊断，病理诊断当然是最准确的，但有时亦需结合临床加以考虑。何况大多数病例并不可能，实际上亦不必须取得病理诊断。因此，临床诊断乃是疾病诊疗的基础，亦是每一位临床医师的...
杨秉辉
doaj
Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 5, Page 679-683, May 2026.ABSTRACT ObjectiveTo determine the diagnostic performance of each additional step of the four‐step International Deep Endometriosis Analysis (IDEA) consensus protocol for predicting the presence of deep endometriosis (DE) on transvaginal ultrasound. MethodsThis was an international multicenter observational cohort study of data collected prospectively ...
P. McClenahan +18 more
wiley +1 more source
Peptide‐Coupled Gold Nanoclusters: Syntheses, Properties, and Bioapplications
Rare Metals, Volume 45, Issue 4, April 2026.ABSTRACT Gold nanoclusters (AuNCs) have garnered significant attention in biomedicine. Particularly, peptide‐coupled AuNCs (Pep‐AuNCs) are emerging as a fascinating class of cluster probes that enable highly tailorable design in their optical, catalytic, targeting, and therapeutic capabilities via peptide engineering.
Jie Liu +5 more
wiley +1 more source
亚洲临床医学杂志, 2020 近年来，基因组学、转录组学和蛋白质组学的重大进展改变了我们对肺癌发病机理的分子机制的理解，并正在彻底改变我们的诊断和治疗方法。虽然这些技术传统上被描述为对手术切除的肿瘤进行大体积活检，但重大的技术进步使它们可以应用于支气管镜下获得的较小样本，这通常是晚期肺癌唯一可用的样本。使用先进的分子技术进行组织学检查的手段包括：通过荧光原位杂交技术对非小细胞肺癌的早期诊断和筛查；通过新的免疫组织化学标记进行准确的组织学诊断以及靶向和常规化疗药物的预后和反应预测。分子生物学技术越来越多地应用于较小的活检标本 ...
东海 王 +4 more
semanticscholar +1 more source
Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 4, Page 461-469, April 2026.ABSTRACT Objective The aim of this study was to evaluate the perinatal outcomes of monochorionic diamniotic (MCDA) twin pregnancies complicated by early twin‐to‐twin transfusion syndrome (TTTS) treated with fetoscopic laser surgery (FLS), and to compare rates of fetal survival across Quintero stages.
F. G. Sileo +35 more
wiley +1 more source
Gaoya dianqi, 2015 目前被广泛研究和使用的是融合多种状态量的变压器综合诊断方法,该方法提高了诊断的准确性,但同时也带来了一些问题,主要问题在于这种方法需要的状态量多、诊断效率低、导致停电时间过长。因此,文中提出了一种以不停电检测状态量为主的分步诊断方法,其包括初步诊断和精细诊断两个阶段。初步诊断阶段仅以不停电检测状态量为诊断依据,在无需停电的状态下将变压器故障分为热故障、电故障、受潮或脏污、变形4大类;在精细诊断阶段,根据初步诊断结果,选择出多种必要的停电试验信息,并利用故障机理和粗糙集理论进行进一步的故障确认和细分 ...
孔巾娇 +4 more
doaj
Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 4, Page 455-460, April 2026.ABSTRACT Objective To estimate the residual risk of maternal–fetal transmission after primary cytomegalovirus (CMV) infection in the periconceptional period or the first trimester in women treated with valacyclovir, and to assess whether the presence of glycoprotein B2 (gB2)‐specific immunoglobulin (Ig)‐G antibodies on immunoblot analysis refines fetal
K. O. Kagan +6 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2018 目的研究并探讨G实验与真菌培养联合诊断在艾滋病患者深部真菌感染中的诊断价值。方法于2014年6月-2016年7月,选取120例疑似合并深部真菌感染的艾滋病患者进行G实验检测、真菌培养,以临床综合诊断结果作为金标准,对单一及联合诊断对艾滋病患者深部真菌感染的诊断结果进行分析。结果 120例疑似合并深部真菌感染的艾滋病患者中,共有100例患者经临床综合诊断被证实为深部真菌感染。联合诊断的诊断敏感度明显高于单一的G实验、真菌培养(P0.05),且联合诊断的Youden指数最高,说明其筛查效果最好。G实验 ...
张汇征, 付晓, 万东勇
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