Results 21 to 30 of about 77,530 (174)
ABSTRACT Achieving a simultaneous enhancement in both tribological and mechanical properties of self‐lubricating composites has long been a challenge. In this study, we designed the composition based on first‐principles calculation and fabricated a copper‐based self‐lubricating composite with excellent tribological and mechanical properties via spark ...
Zhongbo Wang +4 more
wiley +1 more source
目的探讨肿瘤坏死因子-α(TNF-α)在内毒素诱导肥大细胞高迁移率族蛋白B1(HMGB1)释放中的作用。方法采用小鼠肥大细胞株P815培养物,观察100μg/L脂多糖(LPS)诱导后培养上清液中HMGB1、TNF-α含量的变化,不同剂量抗TNF-α中和抗体IgG对LPS诱导HMGB1释放的影响,及TNF-α对HMGB1释放的诱导作用。HMGB1含量采用酶联免疫吸附试验检测。结果培养上清液中HMGB1含量随LPS诱导时间而升高,而TNF-α含量于诱导6 h时达到峰值;5、25 mg/L抗TNF ...
杨岚 +4 more
doaj
ABSTRACT Reliable monitoring of ultraviolet (UV) radiation is critical for protecting human health, yet existing sensors often rely on costly or rigid components that hinder portability. Here we report a wearable, low‐cost colorimetric sensor for quantitative UV dosimetry, enabled by radical‐triggered aggregation of gold nanoparticles (AuNPs).
Yahuang Li +6 more
wiley +1 more source
ABSTRACT Te‐free BiSbSe3 is a promising medium‐temperature thermoelectric (TE) material owing to its cost‐effectiveness and intrinsically low lattice thermal conductivity. However, its comparatively low electrical conductivity has severely hindered the optimization of TE performance.
Xiaowei Shi +10 more
wiley +1 more source
研究了不同浓度的Cu、Zn、Pb、Cd(氯化盐)分别对双孢菇菌丝进行短时间(1d)和长时间(8d)诱导时,菌丝体内可溶性蛋白,巯基化合物和抗氧化酶等的变化.结果显示:高浓度的重金属在长时间诱导后显著降低菌丝可溶性蛋白含量;长时间诱导条件下,Cu、Zn显著增加巯基化合物含量,Cd则显著降低巯基化合物含量;超氧化物歧化酶(SOD)在重金属长时间诱导后活性显著增加,Cd诱导增加最明显;经过长时间诱导,低浓度Cu和高浓度Zn显著增加CAT酶活;经过1d和8d诱导后,Pb使CAT酶活性显著提高.
宋鹏 +4 more
doaj
ABSTRACT The strength and ductility trade‐off in titanium matrix composites (TMCs) is a critical factor limiting their widespread application. In this study, a (TiB + TiC)/Ti–6Al–4V composite with an optimal balance between strength and ductility was engineered via multi‐directional forging.
Chunyu Shen +8 more
wiley +1 more source
黄酮与黄酮醇类化合物对HepG2细胞中CYP1A1mRNA表达的影响
目的观察15种黄酮与黄酮醇类化合物对细胞色素P450酶(cytochrome P450,CYP)1A1基因表达的影响。方法采用实时定量PCR技术检测HepG2细胞中各CYP1A1mRNA的表达。结果黄酮、6-羟基黄酮、槲皮素、黄芩素、野黄芩苷、野黄芩素和白杨黄素是CYP1A1的强诱导剂,50uM浓度时诱导超过10倍;黄芩苷是中等程度诱导剂,诱导倍数为7.68;桑黄素、木犀草素、汉黄芩素和山萘酚是CYP1A1弱诱导剂,诱导倍数在2-3倍左右。而7-羟基黄酮、漆黄素、芹菜黄素是CYP1A1的弱抑制剂 ...
郭颖杰, 康治臣, 张家剑, 周慧
doaj
ABSTRACT The electrocatalytic water splitting technique was widely taken for hydrogen evolution, due to its cost‐effectiveness and environmental friendliness. The design of electrode material as electrocatalysts play a key role in achieving high efficiency.
Yaling Zhu +5 more
wiley +1 more source
诱导耐药型宋内志贺菌中主动外排阻遏基因acrR、marR的变化
目的分析宋内志贺菌在被环丙沙星诱导耐药后其主动外排阻遏基因acrR、marR突变与表达量的变化。方法通过1/2MIC逐级诱导宋内志贺菌对环丙沙星耐药,通过提取诱导株诱导前后DNA和总RNA,采用基因测序检测突变和实时荧光定量PCR方法检测acrR、marR基因表达量的变化。结果 2株诱导耐药株中acrR、marR中均不存在基因突变,相对于诱导前acrR、marR Ct值增加,基因表达量降低。结论 acrR、marR基因表达量降低间接导致主动外排基因acrAB-tolC转录水平提高 ...
高佩增, 姚明晓
doaj
ABSTRACT Managing diabetic wounds requires simultaneously addressing their infectious, oxidative, and regenerative impairments. To address this, this study integrates a piezoelectric BiOCl@CuSe heterojunction (PFM‐verified) into an injectable F127/HA hydrogel, creating an ultrasound‐responsive smart dressing.
Jiayan Guo +5 more
wiley +1 more source

