目的探讨乌司他丁在链脲佐菌素(STZ)诱发大鼠糖尿病性心肌病(DCM)后对心肝的影响。方法用STZ诱发DCM模型,48只雄性Wistar大鼠随机分为正常对照组、DCM组(STZ)、阳性药组[STZ+贝那普利组(卡托普利)]及高、中、低治疗组[STZ+乌司他丁)],每组8只。治疗组大鼠给予乌司他丁灌胃,DCM组和正常组大鼠给予0.9%氯化钠注射液灌胃。治疗2周后测定大鼠体重、血糖、形态学及Rock I蛋白的表达。结果注射STZ后,大鼠体重、血糖值及Rock I蛋白表达较正常对照组增加 ...
李晓华 +8 more
doaj
糖尿病肾病(DN)在糖尿病患者中的发病率可达20%-40%左右[1],是导致患者死亡的主要原因之一,目前已有研究证实其危害性仅次于心脑血管疾病[2]。出现蛋白尿时多提示患者的病程长达5-10年以上,当患者表现为持续性蛋白尿时,可出现肾功能不可逆性损害,最终发展成为终末期肾病。我们通过前列地尔联合贝那普利对糖尿病肾病患者蛋白尿的影响进行分析,现报道如下。1资料与方法1.1一般资料2011年1月至2014年1月 ...
姬静, 朱沛宁, 刘大海
doaj
Chinese herbal medicine for diabetic kidney disease: historical perspective, clinical evidence and new therapeutic development [PDF]
Diabetic kidney disease (DKD) is the foremost microvascular complication of diabetes mellitus, which is characterised as persistent albuminuria and progressive loss of kidney function induced by diabetes.
Zhang, L
core
[Liquid chromatography-high resolution mass spectrometry analysis of 300 illegally added drugs and their analogues in functional milk powder for the elderly]. [PDF]
Ning X +5 more
europepmc +1 more source
Evaluation of anticholinergic burden in elderly outpatients and the risk factors. [PDF]
Lu X +6 more
europepmc +1 more source
[Clinical features of children and their family members with family clusters of SARS-CoV-2 Omicron variant infection in Shanghai, China: an analysis of 380 cases]. [PDF]
Bian XL +11 more
europepmc +1 more source
[Oral panorama reconstruction method based on pre-segmentation and Bezier function]. [PDF]
Hou C +5 more
europepmc +1 more source
Recent research on the treatment of spinal muscular atrophy. [PDF]
Yang DL.
europepmc +1 more source
The past, present and future of tuberculosis treatment. [PDF]
Bi K +10 more
europepmc +1 more source
[Multiple myeloma with chromothripsis: three cases report]. [PDF]
Wu CX +10 more
europepmc +1 more source

