A meta-analysis of Pemetrexed plus Platinum Chemotherapy versus Gemcitabine plus Platinum Chemotherapy for Advanced Non-small Cell Lung Cancer [PDF]
Background and objective Whether pemetrexed plus platinum (PP) regimen is superior to gemcitabine plus platinum (GP) regimen for patients with advanced non-small cell lung cancer (NSCLC) is unclear.
Jin JIANG +5 more
core
Fetal and neonatal neuroimaging in twin–twin transfusion syndrome
ABSTRACT Objectives To describe the types of brain injury and subsequent neurodevelopmental outcome in fetuses and neonates from pregnancies with twin–twin transfusion syndrome (TTTS). Additionally, to determine risk factors for brain injury and to review the use of neuroimaging modalities in these cases.
M. S. Spruijt +8 more
wiley +1 more source
Role of P97 in non-transferrin bound iron uptake by rabbit reticulocytes [PDF]
2000-2001 > Academic research: refereed > Publication in refereed journalVersion of ...
Chen, WF, Qian, ZM
core
On the Generation of Medical Question-Answer Pairs
Question answering (QA) has achieved promising progress recently. However, answering a question in real-world scenarios like the medical domain is still challenging, due to the requirement of external knowledge and the insufficient quantity of high ...
Du, Nan +9 more
core +1 more source
Abstract In response to the issue of Chinese language teacher attrition in Myanmar, this study aimed to examine the professional commitment of these teachers, with a focus on how their commitment is constructed and shaped within the local context. The study adopted a theoretical lens of positive psychology and utilized a hermeneutic phenomenological ...
Yue Peng, Kaiyang Lou, Tao Xiong
wiley +1 more source
Studies of Hyperaccumulation Mechanism of Eucalyptus grandis×E. urophylla to Manganese and Arabidopsis Transporter’s Functions on Metal Transportation and Signaling [PDF]
重金属污染已经成为世界性问题,严重威胁人体健康,已引起广泛的关注。植物修复技术作为一种经济、环境友好的土壤污染治理途径,也引起越来越多人的兴趣。只有寻找到更多合适的超富集植物,并且深入研究重金属的耐受和吸收、转运途径,才能有效地控制重金属对作物的污染或者更好发挥超富集植物的修复潜能。 本论文通过矿区筛选,发现了新的诱导型锰超富集植物-巨尾桉。该植物可以在叶片富集大量锰元素。通过实验室水培和ICP-MS联用技术研究其对锰的耐受性、在各组织中的分异 ...
谢清清
core
The role of TNFAIP8 family in gastric cancer and heart transplantation [PDF]
摘要 目的:TIPE及TIPE2是TNFAIP8(Tumornecrosisfactor-αinducedprotein-8,TIPE,TNFAIP8)家族的重要成员,TIPE是调控凋亡进程的重要分子,本研究之一是应用TIPE不同表达的BGC823细胞株建立胃癌裸鼠移植瘤模型,观察TIPE对移植瘤生长的影响;同时收集并检测胃癌临床标本TIPE的表达特点,分析TIPE与胃癌临床病理特征的关系,明确TIPE与胃癌生物学行为的关系及对胃癌生长的影响。 TIPE2为免疫负性调控因子,对免疫稳态的维持起重要作用 ...
洪诗福
core
The role of appoptosin in regulating oxidative stress and mitochondrial morphology [PDF]
氧化压力是指细胞或体内氧自由基的含量超出抗氧化物及抗氧化酶类清除能力时对细胞或机体造成的氧化胁迫。氧化压力参与了包括炎症、衰老、心血管疾病、癌症、糖尿病、艾滋病、神经退行性疾病等多种疾病的发病过程。氧化压力通过多个下游信号通路对细胞造成胁迫,如JNK、Foxo等,但其中的具体参与蛋白仍有待于深入阐明。Appoptosin也被称为SLC25A38,是一种定位于线粒体内膜的转运蛋白,负责转入甘氨酸并转出D-氨基乙酰丙酸,进而调节血红素(heme)的合成 ...
张翠林
core
目的探讨缺铁性贫血对不同基因型α地中海贫血筛查的影响,评估HbA2与红细胞各指标在鉴别缺铁性贫血和各种基因型α地中海贫血中的作用。方法严格筛选正常人群样本、α地中海贫血患者样本、缺铁性贫血患者样本和α地中海贫血合并缺铁性贫血患者样本,进行血红蛋白电泳、血常规、铁蛋白和地中海贫血基因诊断,统计分析不同检测指标在各样本组差异。结果缺铁性贫血的HbA2平均水平低于α地中海贫血,HbH病患者HbA2水平低于缺铁性贫血。鉴别正常人群和单纯α地中海贫血时,MCH比MCV有更高的敏感性。鉴别α地中海贫血和缺铁性贫血时,
陈卫东, 周宇, 王秋
doaj
Immediate Versus Delayed Topotecan after First-line Therapy in Small Cell Lung Cancer [PDF]
Background and objective How to prolong progression free survival (PFS) and overall survival (OS) of patients with small cell lung cancer (SCLC) has been one of the hottest issues. We retrospectively reviewed our data to compare the survival of immediate
Cong XUE +7 more
core

