[Expert consensus in Southwest China on the application of botulinum toxin type A in upper and mid-facial aesthetics]. [PDF]
Hua Xi Kou Qiang Yi Xue Za ZhiSichuan Provincial Medical Association Medical Aesthetics and Cosmetology Specialty Committee.
europepmc +1 more source
蛙虹彩病毒3β-羟基类固醇脱氢酶抑制鱼弹状病毒引起的细胞凋亡
, 2008 设计保守引物从蛙虹彩病毒(RGV)中克隆到3β-羟基类固醇脱氢酶(3β-HSD)基因,将其亚克隆到真核表达载体 pcDNA3.1上,构建重组质粒 pcDNA3.1-HSD,经酶切分析和 DNA 测序表明其读码框正确。将 pcDNA3.1-HSD 和 pcDNA3 ...
张奇亚, 孙伟
core
[Global burden and predicted trends of diarrheal disease in children under five from 1990 to 2021]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoDeng Y +6 more
europepmc +1 more source
草鱼出血病病毒873株基因组外发现缺损性干扰颗粒的亚基因组成份
, 2001 草鱼出血病病毒基因组由 11条dsRNA片段组成。最近在研究其基因组时发现 ,在病毒基因组外存在许多核酸成份 ,但在核苷酸数量上少于基因组成份 ,表现为较小分子量的RNA片段。在完整地克隆了这些片段的全长cDNA后 ,测定了其中两个克隆的序列组成 ,发现它们为病毒基因组经剪切后的部分片段 ,已经重新装配 ,而且都含有原基因组某一片段 3′端和 5′端的保守区和倒转重复区 ,缺失中间部分。根据其特点来看 ,它们应为目前病毒学研究的重要材料——&mdash ...
朱作言, 邱涛, 张菁, 陆仁后
core
[Association Between Marital/Partner Relationship Quality and Accumulation Rate of Multiple Chronic Conditions in Middle-Aged and Older Adults: An Analysis Based on Data From English Longitudinal Study of Ageing]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanChen R, Xiang Y, Xin M, Xiao X.
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[Expert recommendations on the first-line use and optimization plan of nucleos(t)ide analogues in the context of functional cure for chronic hepatitis B]. [PDF]
Zhonghua Gan Zang Bing Za ZhiLiver Cancer Study Group +2 more
europepmc +1 more source
, 2000 中华鳖病毒（ＴＳＶ）是从病鳖中分离到的一种病毒病原。经细胞培养和差异离心制备ＴＳＶ抗原，肌注家兔获 ＴＳＶ抗体（ＴＳＶ－Ａｂ），中和效价为 １：２０。用 ＴＳＶ－Ａｂ进行双向免疫扩散和间接ＥＬＩＳＡ检测，被检样品有健康和病鳖组织匀浆液、ＴＳＶ细胞培养液、提纯的ＴＳＶ，以及鱼传染性胰脏坏死病毒（ＩＰＮＶ）、草鱼呼肠孤病毒（ＧＣＶ）、鱼病毒性出血败血症病毒（ＶＨＳＶ）、鲤痘疮病毒（Ｃａｒｐ ｐｏｘ ｖｉｒｕｓ）和斑节对虾杆状病毒（ＭＢＶ）。检测结果显示：ＩＰＮＶ、ＧＣＶ、ＶＨＳＶ、Ｃａｒｐ ｐｏｘ ...
张奇正,李正秋,胡峻
core
[The E3 ubiquitin ligase KLHL8 degrades HBx protein via the ubiquitin-proteasome pathway and inhibits HBV cccDNA transcription]. [PDF]
Zhonghua Gan Zang Bing Za ZhiLiu ZH +6 more
europepmc +1 more source
, 2003 紫外线灭活的草鱼出血病病毒(GCHV)能诱导鲫鱼囊胚培养细胞(CAB)产生高滴度的干扰素并抵抗病毒入侵,其机制可能是通过诱导一组抗病毒相关基因的表达,而使寄主细胞建立起抗病毒状态.利用抑制性差减杂交技术,构建了灭活病毒诱导鱼类培养细胞基因差异表达的差减cDNA文库.从差减文库中筛选鉴定出272个差异cDNA片段,测序分析发现它们为69个基因,其中46个为已知基因的同源物,23个为未知的假定基因.已知基因包括I型干扰素信号通路的基因Statl和JakI,抗病毒基因Mx和Viperin ...
张义兵,张奇亚,徐德全,胡成钰,桂建芳
core
[Expert recommendations on the management of adverse reactions in pegylated interferon alpha therapy for chronic hepatitis B]. [PDF]
Zhonghua Gan Zang Bing Za ZhiExpert Group on the Management of Adverse Reactions in Pegylated Interferon Alpha Therapy for Chronic Hepatitis B.
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