, 2013 本文分别考察了非对称杂化的手性膦-胺基膦配体在铱催化的2(H)-1,4-苯并噁嗪衍生物以及手性膦-亚磷酰胺酯配体在铑催化的-烯醇酯膦酸酯的不对称氢化反应中的应用，并评选出高活性的催化剂体系。 1. 在2(H)-1,4-苯并噁嗪类底物的不对称催化氢化反应研究中，发现 [Ir(COD)Cl]2与1,2,3,4-四氢萘胺衍生的膦-胺基膦配体(Rc)-HWPhos (L2-12a)原位生成的催化剂显示出优异的催化活性和立体选择性。在优化的反应条件下，能对一系列3-芳基-2(H)-1,4 ...
胡 娟
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[<i>Jianwei Shoutai</i> Pill reduces spontaneous abortion in mice by inhibiting Exo-miR-410-3p uptake and promoting trophoblast epithelial-mesenchymal transition, migration, and invasion]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoXu Z, Chen Z, Xie L, Li X, Qin G, Gao J.
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不同配伍柴郁温胆汤对抑郁模型大鼠海马CREB和BDNF表达的影响
, 2011 目的观察柴郁温胆汤及其不同配伍组合对抑郁模型大鼠海马环磷酸腺苷反应元件结合蛋白(CREB)和脑源性神经营养因子(BDNF)表达的影响。方法健康雄性SD大鼠70只,随机分为正常组、模型组、复方组、化痰组、调气血组、养心脾组和马普替林组。除正常组外,各组采用孤养加慢性轻度不可预见性刺激方法建立大鼠抑郁模型,从应激第2天起分别灌胃给药至实验第23天。采用免疫组化法检测大鼠海马CA3区CREB和BDNF的表达。结果与正常组相比,模型组大鼠海马CREB和BDNF表达的总面积、阳性细胞数和平均光密度均明显降低 ...
周海虹 +5 more
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[A new method for extracting adult mouse cardiac fibroblasts more efficiently and stably]. [PDF]
Beijing Da Xue Xue Bao Yi Xue BanMa X +10 more
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, 2007 本发明公开一种基于脯胺醇的手性磺酰胺胺醇配体及制备方法和应用，配体骨架含1-3个手性中心。制备方法用L-脯胺醇，通过对相应的环乙亚胺进行选择性开环反应得到。该合成方法具有原子经济性且有较高的收率。本发明的手性磺酰胺胺醇配体及其类似物在不对称合成反应中可作为催化剂配体，广泛用于不对称二乙基锌加成，炔基锌对羰基化合物的加成反应，还原反应和醇醛缩合等重要有机合成反应中 ...
吴 凡, 陆世维, 毛金成, 万伯顺
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[Catalpol reduces liver toxicity of triptolide in mice by inhibiting hepatocyte ferroptosis through the SLC7A11/GPX4 pathway: testing the <i>Fuzheng Zhidu</i> theory for detoxification]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoZhang L, Li C, Huang L, Zhou X, Lou Y.
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[Differences in the formation mechanism of performance-based compensation in public hospitals with different administrative affiliations]. [PDF]
Beijing Da Xue Xue Bao Yi Xue BanZhang Y +5 more
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XuanHuGPT: parameter-efficient fine-tuning of large language model in the field of traditional Chinese medicine. [PDF]
Chin MedTong X +9 more
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[Application of Domestic Robotic Surgical Systems in Gynecologic Surgery]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanPeng H, Zheng Y.
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[Tongdu Zhiyu Acupuncture Improves Post-Stroke Depression by Upregulating miR-223-3p and Inhibiting NLRP3 Inflammasome: A Clinical Study]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanZhang J +7 more
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