Results 21 to 30 of about 1,550 (147)
拟穴青蟹抗菌肽Crustin新变体的表达特性与抗菌功能 [PDF]
Crustins是一类较早发现并广泛分布在甲壳动物中且富含半胱氨酸的阳离子抗菌肽,能够参与抗细菌的免疫应答。从拟穴青蟹(Scylla paramamosain)中克隆获得Crustin基因,命名为SpCrus1a,其cDNA序列全长744 bp,开放阅读框编码113个氨基酸,成熟肽分子量10.03 kDa,等电点8.30。表达分析结果发现其转录本主要存在于鳃、卵巢、上皮组织中,脂多糖刺激后SpCrus1a会上调表达。体外合成SpCrus1a的第29~47位氨基酸进行抗菌活性实验发现 ...
张财亮 +4 more
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应用介质阻挡放电(DBD)和介质阻挡电晕放电 (DBCD)产生的低温等离子体,对金黄色葡萄球菌和大肠杆菌进行杀灭试验的结果发现,在90s内DBD和DBCD都对金黄色葡萄球菌和大肠杆菌的杀灭对数值KL达到了5。 DBCD使两种菌株减少的速度大于DBD。DBD和DBCD都使大肠杆菌减少的速度大于金黄色葡萄球菌。
石兴民 +4 more
doaj
Fabrication and Antibacterial Performance of Pea Protein Isolate/Pullulan/Allicin Composite Electrospun Nanofibers [PDF]
Using pea protein isolate (PPI) and pullulan (PUL) as raw materials and allicin (AC) as an antibacterial substance, nanofiber materials were prepared by electrospinning technology.
JIA Xiwen, LIU Jiuyang, WANG Jingjie, LIU Qian, WANG Hao, KONG Baohua, WANG Hui
core +1 more source
近年来随着广谱抗菌药物在临床的广泛应用,使院内感染的病原菌种类发生了变化,尤其是经历外科手术和静脉置管的患者,革兰阳性球菌特别是金黄色葡萄球菌所占比例在提高[1]。为确切了解我院外科金黄色葡萄球菌特别是甲氧西林耐药的金黄色葡萄球菌(MRSA)分离比例及药物敏感情况,现统计了近八年来的数据为临床提供参考。
岳志刚
doaj
The optimized expression technology of marine animal-sourced antimicrobial peptides in Pichia pastoris and the development of antimicrobial peptide as feedstuff additive [PDF]
抗生素污染问题是目前影响我国水产养殖业可持续健康发展的重大科技问题,抗生素(antibiotics)作为常用抗菌药物,被广泛应用于水产养殖业,但是抗生素超标所引起的细菌耐药性问题已成为全球公共健康问题,因此寻找抗生素的有效替代品是目前国内外本领域的研究热点之一。抗菌肽(antimicrobialpeptide)是先天性免疫的重要组分,广泛存在于生物界的各个门类,进化上相对保守,具有广谱抗菌活性、且不会产生细菌耐药性,被预言为最有希望替代抗生素的天然药物,具有广阔的应用前景 ...
彭会
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Analysis of Staphylococcus aureus infection and enterotoxin gene carriage in diarrhoeal patients in Jiading District, Shanghai [PDF]
ObjectiveTo investigate the prevalence of Staphylococcus aureus in patients with diarrhea, and to analyze the genes carriage of enterotoxin in the strains of these patients in Jiading District, Shanghai.MethodsFrom 2021 to 2023, anal swabs of diarrhea ...
CHEN Huijuan +6 more
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目的评价胶体金法检测耐甲氧西林金黄色葡萄球菌(MRSA)和耐甲氧西林凝固酶阴性葡萄球菌(MRCNS)临床应用价值。方法采用头孢西丁纸片扩散法、PCR扩增mecA基因和胶体金法对临床分离的150株金黄色葡萄球菌(100株MRSA和50株MSSA)、68株溶血葡萄球菌(58株MRSH和10株MSSH)、135株表皮葡萄球菌(97株MRSE和38株MSSE)进行检测并作比较。结果 MRSA、MSSA、MRSE、MSSE、MSSH三种方法检测结果一致。58株MRSH中6株胶体金法检测阴性 ...
黄艳飞 +6 more
doaj
Contamination of Staphylococcus aureus in food sold in Jiading District, Shanghai from 2021 to 2023 [PDF]
ObjectiveTo investigate the contamination status of Staphylococcus aureus in food and the presence of enterotoxin genes in Jiading District, Shanghai, and to provide a basis for the prevention and treatment of foodborne Staphylococcus aureus disease ...
CHEN Huijuan +6 more
core +1 more source
Analysis of monitoring results of foodborne pathogens in infant food on the market of Guangxi Zhuang Autonomous Region in 2011-2016 [PDF]
Objective To understand the contamination status and trend of foodborne pathogens in infant food in Guangxi Zhuang Autonomous Region, and provide reference to prevent and control the foodborne disease effectively.
Chengyuan WEI +4 more
core +1 more source
随着抗菌药物的滥用,细菌耐药现象日趋严重,尤其是革兰阳性致病菌,如金黄色葡萄球菌,凝固酶阴性葡萄球菌和肠球菌,并导致多重耐药菌株(如耐甲氧西林金黄色葡萄球菌,MRSA)的产生。临床上治疗MRSA的首选对策就是万古霉素。但是万古霉素的不合理使用,进一步导致耐万古霉素菌株或者万古霉素中介的菌株产生 ...
程欣 +7 more
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